Results 251 to 260 of about 1,125,892 (364)

Faculty Opinions recommendation of N-cadherin-dependent cell-cell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts.

, 2002
Vania Braga
openalex   +2 more sources

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

Advanced Science, EarlyView.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar, Hayk Mnatsakanyan, Sai Kulkarni, John Guo, Kai Cheng, Luke Daniel Ofria, Oce Bohra, Ram Sagar, Vasiliki Mahairaki, Christian E Badr, Annie Kathuria   +10 more
wiley   +1 more source

Beta-Catenin Positive Giant Cell Tumor of Bone with Pathological Fracture Treated with Neoadjuvant Denosumab Therapy for Visualizing Extraskeletal Lesions. [PDF]

Case Rep Oncol
Ogawa I, Kaneuchi Y, Hakozaki M, Sato S, Suzuki T, Yamada S, Hasegawa O, Nikaido T, Matsumoto Y.   +8 more
europepmc   +1 more source

The Wnt/Beta-Catenin Pathway and Cytoskeletal Filaments Are Involved in the Positioning, Size, and Function of Lysosomes during Chick Myogenesis. [PDF]

Cells, 2022
Bagri KM, Oliveira LF, Pereira MG, Abreu JG, Mermelstein C.   +4 more
europepmc   +1 more source

TRANSACTIVATION OF VIMENTIN BY BETA-CATENIN IN HUMAN BREAST CANCER CELLS

, 2003
Christine Gilles, Myriam Polette, Mélanie Mestdagt, Béatrice Nawrocki‐Raby, Philippe Ruggeri, Philippe Birembaut, Jean‐Michel Foidart   +6 more
openalex   +1 more source

Macrophage Derived Galectin‐3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling

Advanced Science, EarlyView.
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen, Qian Jiang, Xiaowei Xing, Liu Xu, Qijin Zhao, Qidong Zhang, Jingwen Chen, Chunxiao Ma, Xingfeng Liu, Yinfei Lu, Yanjun Wan, Lijuan Kong, Shaocong Hou, Qian Lu, Bing Cui, Jiankan Guo, Hongdong Huang, Pingping Li   +17 more
wiley   +1 more source

Inhibition of beta-catenin shows therapeutic potential in head and neck squamous cell carcinoma in vitro. [PDF]

Eur Arch Otorhinolaryngol, 2023
Maier T, Stoiber S, Gurnhofer E, Haas M, Kenner L, Heiduschka G, Kadletz-Wanke L, Brkic FF.   +7 more
europepmc   +1 more source

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

Advanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang, Kaifan Niu, Wei Liu, Xinyun Wang, Boshen Yang, Taixi Li, Yizhi Chen, Yuanyuan Jin, Yu Chen, Yangyi Lin, Xian Jin   +10 more
wiley   +1 more source

Ergosterol inhibits the proliferation of breast cancer cells by suppressing AKT/GSK-3beta/beta-catenin pathway. [PDF]

Sci Rep
Nilkhet S, Vongthip W, Lertpatipanpong P, Prasansuklab A, Tencomnao T, Chuchawankul S, Baek SJ.   +6 more
europepmc   +1 more source

Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK‐3β/β‐Catenin Signaling

Advanced Science, EarlyView.
FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan, Dan Guo, Songtao Li, Jinmiao Tian, Chaotong Zhang, Zhuoyu Li   +5 more
wiley   +1 more source