Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery [PDF]
Cyclodextrin polymers have high applicability in pharmaceutical formulations due to better biocompatibility, solubility enhancement, loading capacity and controlled drug release than their parent, cyclodextrins.
Giovanna Rassu +7 more
doaj +2 more sources
Bisphenol A Adsorption on Silica Particles Modified with Beta-Cyclodextrins [PDF]
This study presents the synthesis of silica particles bearing two beta-cyclodextrin (BCD) (beta-cyclodextrin-BCD-OH and diamino butane monosubstituted beta-cyclodextrin-BCD-NH2).
Stefan Bucur +9 more
doaj +2 more sources
Compared to beta-cyclodextrins (beta-CD), hydroxypropyl-beta-cyclodextrins (HP-beta-CD) are a more popular material used to prepare inclusion complexes due to their superior solubility and intestinal absorption.
Hui Liu +5 more
doaj +3 more sources
Fluorescently labeled methyl-beta-cyclodextrin enters intestinal epithelial Caco-2 cells by fluid-phase endocytosis. [PDF]
Cyclodextrins are widely used excipients for increasing the bioavailability of poorly water-soluble drugs. Their effect on drug absorption in the gastrointestinal tract is explained by their solubility- and permeability-enhancement.
Ferenc Fenyvesi +12 more
doaj +4 more sources
Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. [PDF]
2-Hydroxypropyl-beta-cyclodextrin (HPβCD) has gained recent attention as a potential therapeutic intervention in the treatment of the rare autosomal-recessive, neurodegenerative lysosomal storage disorder Niemann-Pick Disease Type C1 (NPC1).
Alfred L Yergey +5 more
doaj +2 more sources
Correction: Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. [PDF]
[This corrects the article DOI: 10.1371/journal.pone.0175478.].
Alfred L Yergey +5 more
doaj +2 more sources
Linked Beta-Cyclodextrins [PDF]
ChemistryMaster of Arts (M.A.
Nemeth, Richard Desider
core +3 more sources
Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins via complexation [PDF]
The solubility of commonly used anti-inflammatory drugs has become a significant concern in contemporary medicine. Furthermore, inflammatory arthritis stands out as the most prevalent chronic inflammatory disease globally.
Rajaram Rajamohan +7 more
doaj +2 more sources
Antimicrobial Activities of Pistacia lentiscus Essential Oils Nanoencapsulated into Hydroxypropyl-beta-cyclodextrins [PDF]
Obaydah Abd Alkader Alabrahim +1 more
doaj +2 more sources
Cellular Effects of Cyclodextrins: Studies on HeLa Cells
Cyclodextrins are high molecular weight, hydrophilic, cyclic, non-reducing oligosaccharides, applied as excipients for the improvement of the solubility and permeability of insoluble active pharmaceutical ingredients.
Ágnes Rusznyák +11 more
doaj +1 more source

