Results 1 to 10 of about 6,344 (211)

Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery [PDF]

open access: yesPharmaceutics, 2020
Cyclodextrin polymers have high applicability in pharmaceutical formulations due to better biocompatibility, solubility enhancement, loading capacity and controlled drug release than their parent, cyclodextrins.
Giovanna Rassu   +7 more
doaj   +2 more sources

Bisphenol A Adsorption on Silica Particles Modified with Beta-Cyclodextrins [PDF]

open access: yesNanomaterials, 2021
This study presents the synthesis of silica particles bearing two beta-cyclodextrin (BCD) (beta-cyclodextrin-BCD-OH and diamino butane monosubstituted beta-cyclodextrin-BCD-NH2).
Stefan Bucur   +9 more
doaj   +2 more sources

Stability, Antioxidant Activity and Intestinal Permeation of Oleuropein Inclusion Complexes with Beta-Cyclodextrin and Hydroxypropyl-Beta-Cyclodextrin

open access: yesMolecules, 2022
Compared to beta-cyclodextrins (beta-CD), hydroxypropyl-beta-cyclodextrins (HP-beta-CD) are a more popular material used to prepare inclusion complexes due to their superior solubility and intestinal absorption.
Hui Liu   +5 more
doaj   +3 more sources

Fluorescently labeled methyl-beta-cyclodextrin enters intestinal epithelial Caco-2 cells by fluid-phase endocytosis. [PDF]

open access: yesPLoS ONE, 2014
Cyclodextrins are widely used excipients for increasing the bioavailability of poorly water-soluble drugs. Their effect on drug absorption in the gastrointestinal tract is explained by their solubility- and permeability-enhancement.
Ferenc Fenyvesi   +12 more
doaj   +4 more sources

Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. [PDF]

open access: yesPLoS ONE, 2017
2-Hydroxypropyl-beta-cyclodextrin (HPβCD) has gained recent attention as a potential therapeutic intervention in the treatment of the rare autosomal-recessive, neurodegenerative lysosomal storage disorder Niemann-Pick Disease Type C1 (NPC1).
Alfred L Yergey   +5 more
doaj   +2 more sources

Correction: Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. [PDF]

open access: yesPLoS ONE, 2018
[This corrects the article DOI: 10.1371/journal.pone.0175478.].
Alfred L Yergey   +5 more
doaj   +2 more sources

Linked Beta-Cyclodextrins [PDF]

open access: yes, 1988
ChemistryMaster of Arts (M.A.
Nemeth, Richard Desider
core   +3 more sources

Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins via complexation [PDF]

open access: yesScientific Reports
The solubility of commonly used anti-inflammatory drugs has become a significant concern in contemporary medicine. Furthermore, inflammatory arthritis stands out as the most prevalent chronic inflammatory disease globally.
Rajaram Rajamohan   +7 more
doaj   +2 more sources

Cellular Effects of Cyclodextrins: Studies on HeLa Cells

open access: yesMolecules, 2022
Cyclodextrins are high molecular weight, hydrophilic, cyclic, non-reducing oligosaccharides, applied as excipients for the improvement of the solubility and permeability of insoluble active pharmaceutical ingredients.
Ágnes Rusznyák   +11 more
doaj   +1 more source

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