Results 91 to 100 of about 574,698 (305)

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Beta-Cyclodextrin in DNA decompaction An imaging approach

Frontiers in Bioscience, 2010
In the present work we investigate the CTAB:DNA complexes decompaction process using beta-CD as a decompacting agent. The transition from globules (compacted DNA) to coils (decompacted DNA) was achieved without a coexistence region between coils and globules.
openaire   +2 more sources

Phi Beta Kappa: The Key Reporter Winter 2012-2013

, 2012
Announcement of the Beta of Nebraska chapter installation at Creighton University, p.
Phi Beta Kappa Society
core  

Real‐Time Stress Visualization of Hydrogels Enabled by Supramolecularly Switched Stretch‐Induced Phase Separation

Advanced Science, EarlyView.
Supramolecular hydrogels enable real‐time visualization of mechanical stress through supramolecular switching mechanotransduction. Adamantane‐modified cellulose functions as a responsive domain that undergoes an on–off transition between hydrated and dehydrated states via reversible β‐cyclodextrin–adamantane complexation and decomplexation.
Sooyeon Noh, Akihide Sugawara, Naoaki Ishihara, Takashi Konishi, Yuki Ueda, Ryuhei Motokawa, Yoshinori Takashima, Hiroshi Uyama   +7 more
wiley   +1 more source

Harnessing cyclodextrins for enhanced ocular delivery of carotenoid derivatives: From development to ex vivo characterization

Carbohydrate Polymer Technologies and Applications
Lutein and zeaxanthin, prominent carotenoids with antioxidant properties, contribute notably to maintaining of ocular health. These substances reduce the harmful effect of oxidative stress and blue light and ensure the vision quality.
Réka Angi, Attila János Kalóczkai, Anna Kovács, András Marton, Vivien Bárdos, Péter Dormán, Gábor Katona, Attila Agócs, Anita Csorba, Zoltán Zs. Nagy, Anna Vincze, György T. Balogh   +11 more
doaj   +1 more source

Phi Beta Kappa

, 1905
Phi Beta Kappa was founded by five students at the College of William and Mary in 1776. This minute book documents the organization in the period 1905-1928.
Phi Beta Kappa, College of William and Mary. Students   +1 more
core  

Optimization of a method for preparing solid complexes of essential clove oil with beta-cyclodextrins [PDF]

, 2017
Essential CO was successfully solubilized in aqueous solution by forming inclusion complexes with beta-cyclodextrins (beta-CDs). Moreover, phase solubility studies demonstrated that essential CO also forms insoluble complexes with beta-CDs.
Hernández Sánchez, Pilar
core   +1 more source

Response of an Infant With Presumed Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta, Kaitlyn N. Bloom, Jerry Vockley, Angela R. Grochowsky, Neena S. Agrawal, Ellen W. Strickler, Natalie N. Owen, Erica T. Gray, B. Lakshitha A. Perera, Eric R. Gamazon, Lynette C. Rives, Hua‐Chang Chen, Qi Liu, Rizwan Hamid, Joy D. Cogan, John A. Phillips III, Thomas A. Cassini, Bryce A. Schuler   +17 more
wiley   +1 more source

Evaluation of octyl p-methoxycinnamate included in liposomes and cyclodextrins in anti-solar preparations: preparations, characterizations and in vitro penetration studies

International Journal of Nanomedicine, 2012
Mariana Sato de Souza de Bustamante Monteiro,1 Rafael Antonio Ozzetti,2 André Luiz Vergnanini,2 Lycia de Brito-Gitirana,3 Nadia Maria Volpato,4 Zaida Maria Faria de Freitas,1 Eduardo Ricci-Júnior,1 Elisabete Pereira dos ...
Monteiro MS, Ozzetti RA, Vergnanini AL, de Brito-Gitirana L, Volpato NM, de Freitas ZM, Ricci-Júnior E, dos Santos EP   +7 more
doaj  

Formulation and Characterization of Bilastine – Ternary Cyclodextrin Inclusion Complex

Iraqi Journal of Pharmaceutical Sciences
Bilastine (BLA)  is a modern second – generation antihistamine employed to manage symptoms associated with allergic rhinoconjuctivitis and urticaria. However, it is very slightly soluble in water with low bioavailability, which affects its therapeutic ...
Eman B. H. Al-Khedairy, Sura Salam Hatam   +1 more
doaj   +1 more source