Results 71 to 80 of about 574,698 (305)

Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations

Angewandte Chemie, EarlyView.
Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera, Francesco Basoccu, Andrea Porcheddu   +2 more
wiley   +2 more sources

Detection of Odorant Molecules in the Gaseous Phase Using α-, β-, and γ-Cyclodextrin Films on a Quartz Crystal Microbalance

Technologies, 2018
There is an interest in sensors for the detection of odorant molecules in the gaseous phase, especially those related to the fragrance of fruits, because odorant sensing is useful for on-site quality control of agricultural products.
Kai Sasaki, Hiroyuki Furusawa, Kuniaki Nagamine, Shizuo Tokito   +3 more
doaj   +1 more source

Targeted Cyclodextrins.

, 2011
Since 1970s cyclodextrins (CDs) and their derivatives, in virtue of their peculiar inclusion properties, have been proposed as pharmaceutical excipients and have found application in several marketed products.
SALMASO, STEFANO, Salmaso, S, SONVICO, Fabio, F. Sonvico, S. Salmaso, Stefano Salmaso, Fabio Sonvico, Sonvico, F   +7 more
core   +1 more source

Cancer‐Associated Fibroblast‐Derived Sphingosine‐1‐Phosphate Activates a MALL–SDC4 Axis to Facilitate Perineural Invasion in Pancreatic Cancer

Advanced Science, EarlyView.
CAF‐derived S1P activates the S1PR3‐JNK‐Jun signaling pathway, thereby transcriptionally upregulating MALL expression in cancer cells. MALL increases the cell‐surface abundance of SDC4 by promoting its recycling and restricting its lysosomal degradation, which in turn enhances RhoA‐p‐MLC2‐dependent amoeboid invasion and SDC4‐PTN axis‐mediated cancer ...
Wang Peng, Mengdie Cao, Hai Huang, Shuya Bai, Luyao Liu, Jingwen Liang, Haochen Cui, Qiaodan Zhou, Shiru Chen, Jiamei Jiang, Luoxia Liu, Zhou Luan, Wei Chen, Si Xiong, Ronghua Wang, Bin Cheng, Yuchong Zhao   +16 more
wiley   +1 more source

Preparation of tacrolimus ophthalmic solution using cyclodextrins

مجله دانشگاه علوم پزشکی بیرجند, 2017
Background and Aim: Application of topical tacrolimus in Vernal Keratoconjunctivitis is considered as an alternative to steroids. Due to the low aqueous solubility of  the drug, preparing a solution of the drug has got particular importance.
Farzaneh Hajiahmadi, Akbar Derkhshan, Maliheh Nikandish, Bizhan Malaekeh-Nikouei   +3 more
doaj  

Improving the solubility of remdesivir–cyclodextrin encapsulations in water-saturated 1-octanol solution: A molecular dynamics simulation study [PDF]

Pharmacia
Remdesivir was selected as a treatment for viral infections due to its efficacy as an antiviral agent against various RNA viruses such as Ebola and coronaviruses.
Sani Ega Priani, Aulia Fikri Hidayat, Taufik Muhammad Fakih   +2 more
doaj   +3 more sources

Molecular Modelling and 1H-NMR: Ultimate Tools for the Investigation of Tolbutamide: .BETA.-Cyclodextrin and Tolbutamide: Hydroxypropyl-.BETA.-Cyclodextrin Complexes.

Chemical and Pharmaceutical Bulletin, 2001
A structural study of the inclusion compound of tolbutamide (TBM) with beta-cyclodextrin (beta-CD) and hydroxypropyl-beta-cyclodextrin (HP-beta-CD) was attempted by means of 1H-nuclear magnetic resonance (1H-NMR) experiments and computer molecular modelling.
Veiga, Francisco José Baptista, Fernandes, Catarina Marques, Carvalho, Rui Albuquerque, Geraldes, Carlos Frederico Gusmão Campos   +3 more
openaire   +4 more sources

Synergistic Dual Slip‐Link Toughening of a Water‐Rich Double Network Hydrogel Combining Slide‐Ring and Highly Entangled Networks

Advanced Science, EarlyView.
Two distinct slip‐link mechanisms – the slide‐ring pulley effect and highly entangled chains – are combined in a water‐rich double network hydrogel, achieving synergistic toughening, near‐complete reversibility, and exceptional friction tear resistance at >$>$91 wt.% water.
Subhankar Mandal, Saleh Assadi, Aseem Milind Visal, Ignacio Lorente Montero, Franck J. Vernerey, Carson J. Bruns   +5 more
wiley   +1 more source

Large‐Diameter DNA‐Scaffolded Nanopores Enabled by Loosely Packed Peptides for Single‐Molecule Sensing

Angewandte Chemie, EarlyView.
A nanopore composed of transmembrane peptides and a DNA scaffold that assists peptide assembly was constructed. By employing peptides containing the unnatural amino acid 2‐aminoisobutyric acid (Aib), which promotes loose packing between helices, a large‐diameter nanopore was achieved.
Zugui Peng, Daisuke Noshiro, Shiroh Futaki, Ryuji Kawano   +3 more
wiley   +2 more sources

A Comparative Study to Evaluate the Effect of Different Carbohydrates on the Stability of Immunoglobulin G during Lyophilization and Following Storage

Pharmaceutical Sciences, 2016
Background: Although the stabilizing effects of cyclodextrins (CDs) on the liquid protein formulations have been proven, there is no comprehensive data on evaluation of their effects on the lyophilized antibody powders.
Homa Faghihi 1, Sara Merrikhihaghi 1, Abdolhosein Ruholamini Najafabadi 1, Vahid Ramezani 2, Soroush Sardari 3, Alireza Vatanara 1 *
doaj   +1 more source