Optimization of a method for preparing solid complexes of essential clove oil with beta-cyclodextrins [PDF]
, 2017 Essential CO was successfully solubilized in aqueous solution by forming inclusion complexes with beta-cyclodextrins (beta-CDs). Moreover, phase solubility studies demonstrated that essential CO also forms insoluble complexes with beta-CDs.
Hernández Sánchez, Pilar
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Use of cyclodextrins for manipulating cellular cholesterol content
Journal of Lipid Research, 1997 Previous studies from this laboratory have demonstrated that exposure of tissue culture cells to cyclodextrins results in rapid cholesterol depletion.
A E Christian +3 more
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Chemistry Central Journal, 2012 Background The isoflavonoid genistein represents the major active compound from soybean, the vegetal product from Glycine max (Fabaceae). The aim of this study is to prove that genistein was incorporated in two semisynthetic cyclodextrins, beta ...
Danciu CorinaTiulea +6 more
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The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes. [PDF]
, 2015 A novel biocompatible and biodegradable drug-delivery nanoparticle (NP) has been developed to minimize the severe side effects of the poorly water-soluble anticancer drug paclitaxel (PTX) for clinical use.
Chen, R +5 more
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A click chemistry route to 2-functionalised PEGylated and cationic beta-cyclodextrins: co-formulation opportunities for siRNA delivery [PDF]
, 2012 A new approach to the synthesis of amphiphilic beta-cyclodextrins has used 'click' chemistry to selectively modify the secondary 2-hydroxyl group. The resulting extended polar groups can be either polycationic or neutral PEGylated groups and these two ...
Cryan, John F. +5 more
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Biological and Pharmaceutical Bulletin, 1996 The absorption, distribution and excretion of intravenously and orally administered beta-cyclodextrin (beta-CD) and glucosyl (G)-beta-CD in rats were studied using HPLC with pulsed amperometric detection. Within 10 h after intravenous administration, unchanged beta-CD and G-beta-CD recovered in urine were about 90% of each dose.
Y, Kubota +3 more
openaire +3 more sources
Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes. [PDF]
, 2001 Enlarged fat cells exhibit modified metabolic capacities, which could be involved in the metabolic complications of obesity at the whole body level. We show here that sterol regulatory element-binding protein 2 (SREBP-2) and its target genes are induced ...
C. Farnier +7 more
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Molecules, 2018 Puerariae Lobatae Radix (PLR), a well-known herbal medicine, is the root of Pueraria lobata (Willd.) Ohwi and has been employed for the treatment and prevention of cardiovascular and cerebrovascular diseases.
Tao Feng +5 more
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Inclusion complexes of citronella oil with ß-Cyclodextrin for controlled release in biofunctional textiles [PDF]
, 2018 Biofunctional textiles with integrated drug-delivery systems can help in the fight against vector-borne diseases. The use of repellent agents derived from plants and oils is an alternative to DEET (N,N-diethyl-m-methylbenzamide), which has disadvantages ...
Bezerra, Fabricio Maesta +3 more
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Screening of Cyclodextrins in the Processing of Buserelin Dry Powders for Inhalation Prepared by Spray Freeze-Drying [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: In this study, we prepared inhalable buserelin microparticles using the spray freeze-drying (SFD) method for pulmonary drug delivery. Raffinose as a cryoprotectant carrier was combined with two levels of five different cyclodextrins (CDs) and ...
Mostafa Rostamnezhad +5 more
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