Cyclodextrin/poly(anhydride) nanoparticles as drug carriers for the oral delivery of atovaquone. [PDF]
, 2011 The aim was to study the ability of bioadhesive cyclodextrin-poly(anhydride) nanoparticles as carriers for the oral delivery of atovaquone (ATO).
Agüeros, M. (Maite) +3 more
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A Natural Combination Extract of Viscum album L. Containing Both Triterpene Acids and Lectins Is Highly Effective against AML In Vivo [PDF]
, 2015 Aqueous Viscum album L. extracts are widely used in complementary cancer medicine. Hydrophobic triterpene acids also possess anti-cancer properties, but due to their low solubility they do not occur in significant amounts in aqueous extracts.
A Bussing +94 more
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Quality-by-Design Is a Tool for Quality Assurance in the Assessment of Enantioseparation of a Model Active Pharmaceutical Ingredient [PDF]
, 2020 The design of experiments (DoE) is one of the quality-by-design tools valued in analytical method development, not only for cost reduction and time effectiveness, but also for enabling analytical method control and understanding via a systematic workflow,
Aboushady, Dina +2 more
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Mouse sperm membrane potential hyperpolarization is necessary and sufficient to prepare sperm for the acrosome reaction [PDF]
, 2012 Mammalian sperm are unable to fertilize the egg immediately after ejaculation; they acquire this capacity during migration in the female reproductive tract. This maturational process is called capacitation and in mouse sperm it involves a plasma membrane
Darszon, Alberto +7 more
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Technologies, 2018 There is an interest in sensors for the detection of odorant molecules in the gaseous phase, especially those related to the fragrance of fruits, because odorant sensing is useful for on-site quality control of agricultural products.
Kai Sasaki +3 more
doaj +1 more source
Controlling topological entanglement in engineered protein hydrogels with a variety of thiol coupling chemistries [PDF]
, 2014 Topological entanglements between polymer chains are achieved in associating protein hydrogels through the synthesis of high molecular weight proteins via chain extension using a variety of thiol coupling chemistries, including disulfide formation, thiol-
Bradley D. Olsen, Shengchang Tang
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Preparation of tacrolimus ophthalmic solution using cyclodextrins
مجله دانشگاه علوم پزشکی بیرجند, 2017 Background and Aim: Application of topical tacrolimus in Vernal Keratoconjunctivitis is considered as an alternative to steroids. Due to the low aqueous solubility of the drug, preparing a solution of the drug has got particular importance.
Farzaneh Hajiahmadi +3 more
doaj
Improving the solubility of remdesivir–cyclodextrin encapsulations in water-saturated 1-octanol solution: A molecular dynamics simulation study [PDF]
PharmaciaRemdesivir was selected as a treatment for viral infections due to its efficacy as an antiviral agent against various RNA viruses such as Ebola and coronaviruses.
Sani Ega Priani +2 more
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FORMULATION AND EVALUATION OF TAFLUPROST OPHTHALMIC SOLUTION [PDF]
, 2019 The aim of the present study was to formulate, develop and evaluate ophthalmic solution containing Tafluprost. The selected prostaglandin analogue belongs to BCS - II.
Anil Kumar, A. +2 more
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Pharmaceutical Sciences, 2016 Background: Although the stabilizing effects of cyclodextrins (CDs) on the liquid protein formulations have been proven, there is no comprehensive data on evaluation of their effects on the lyophilized antibody powders.
Homa Faghihi 1, Sara Merrikhihaghi 1, Abdolhosein Ruholamini Najafabadi 1, Vahid Ramezani 2, Soroush Sardari 3, Alireza Vatanara 1 *
doaj +1 more source