Results 131 to 140 of about 13,571 (209)

Pulmonary Cryptococcal Infection Complicating Gefitinib Therapy in a Patient With EGFR L858R‐Positive Lung Adenocarcinoma: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In patients with EGFR‐mutant lung adenocarcinoma receiving gefitinib or other EGFR‐TKIs, the development of new pulmonary nodules should not be hastily attributed to disease progression; secondary pulmonary cryptococcosis should be considered in the differential diagnosis.
Yun Wang, Qianyu Wang, Jiangrong Liao, Yuxiang Zhou, Fang Yang, Gui feng Li, Chunyan Wu, Ting Jiang   +7 more
wiley   +1 more source

SYK Signalling in NLRP3 Inflammasome‐Mediated Response of Murine Microglia Activated by Immune Complexes Formed of Viral Proteins and Specific IgG

European Journal of Immunology, Volume 56, Issue 5, May 2026.
IC‐mediated inflammatory response—the NLRP3 inflammasome activation, cytokine secretion, and antigen presentation depend on SYK signalling pathways in primary murine microglia. ABSTRACT Viral infections might trigger systemic inflammatory responses characterised by inflammasome activation and cytokine release, driven by immune complex (IC) formation ...
Kristina Mašalaitė, Milda Norkienė, Aurelija Žvirblienė, Asta Lučiūnaitė   +3 more
wiley   +1 more source

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil, Feng Zhang, Jingchuan Zheng, Muhammad Kamil, Yuwei Guo, Cunchao Zhao, Yang Tian   +6 more
wiley   +1 more source

Natural Products as the Modulators of Gut Microbiota: A Pool for the Development of New Treatment Against Obesity?

Food Frontiers, Volume 7, Issue 3, May 2026.
Natural compounds regulate gut microbiota by improving microbial balance and increasing probiotics, which boost short‐chain fatty acid production to alleviate insulin resistance and inflammation. Additionally, they stimulate appetite‐suppressing hormones through bile acid signaling, while inhibiting pathogenic bacteria to repair intestinal barrier ...
Hongchao Yuan, Yau‐Yuen Chan, Guang Chen, Lin Xu, Cheng Zhang, Guoyi Tang, Yibin Feng, Ning Wang   +7 more
wiley   +1 more source

Enhanced Bioactivity of Puerariae Radix‐ Hovenia Seed Extracts Through Lactiplantibacillus plantarum and Lacticaseibacillus paracasei Co‐Fermentation: Impact on Alcoholic Liver Injury and Macrophage Polarization

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Puerariae Radix and Hovenia Seed were co‐fermented with Lactiplantibacillus plantarum and Lacticaseibacillus paracasei to produce PHF. In a mouse model of alcohol‐induced liver injury, PHF intervention alleviated liver damage. The underlying mechanism may be related to the regulation of macrophage polarization.
Yunpeng Sun, Shen Yao, Yuan Cui, Yiyu Ni, Meichen Liu, Daqing Zhao, Shiting Yu, Siming Wang   +7 more
wiley   +1 more source

Exploring the Functional Potential of Date (Phoenix dactylifera) Seed Bioactives in Modulating Gut Microbiota in Diabetic Rats

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Date fruits (Phoenix dactilyfera L.) are widely produced with huge wasted by‐products (seeds/pits and fibers) in remarkable nutritional and economic potential value. This study aims to examine the impact of the functional properties of date seeds on health status and gut microbiota (GM) modulation in diabetic rats. Valorization of date seed by‐products
Nouf Abdullah Alharbi, Saleh A. Asanie, Asmahan A. Ali, Aeshah Alhosain, Tarfa Albrahim, Thamer Aljutaily, Huda Aljumayi, Isam A. Mohamed Ahmed, Belal M. Mohammed, Nazeha A. Khalil   +9 more
wiley   +1 more source

Differential Safety and Lipid Control Efficacy of β-1,3/1,6-Glucan Oligosaccharides and Polysaccharides Derived From <i>Ophiocordyceps dipterigena</i> BCC 2073 in Healthy Volunteers. [PDF]

Food Sci Nutr
Rungraung N, Muangpracha N, Phucharoenrak P, Prathumpai W, Trachootham D.   +4 more
europepmc   +1 more source

LL‐37: Biological Mechanisms and Emerging Therapeutic Applications in Intestinal Disease

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Human cathelicidin peptide LL‐37 is encoded by the CAMP gene and plays a key role in innate immunity. It maintains intestinal homeostasis through antibacterial, immunomodulation, and tissue repair functions. This paper reviews the multiple functions of LL‐37 in the intestinal‐immune axis and its contribution to intestinal immune homeostasis. A
Qichao Liu, Peng Xu, Cheng Zhang
wiley   +1 more source

Biomolecular Corona Remodelling of Aspergillus fumigatus Extracellular Vesicles Shapes Immune Recognition and Macrophage Activation Programs

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Extracellular vesicles (EVs) released by Aspergillus fumigatus play key roles in fungal–host communication. Similar to synthetic nanoparticles, fungal EVs acquire a biomolecular corona composed of a tightly bound “hard” corona layer of fungal proteins and a dynamic “soft” layer of host‐derived molecules adsorbed upon contact with biological ...
Lucas Fabrício Bahia Nogueira, Bianca T. M. de Oliveira, Renan E. A. Piraine, Lucas de Faria Nogueira, Júlia L. Froldi, Henrique T. de Oliveira, Larwsk Hayann, Luiz H. S. Andrilli, Lucas A. Tavares, Pietro Ciancaglini, Fausto Almeida   +10 more
wiley   +1 more source