Results 141 to 150 of about 577 (171)

Ketogenic Diet and Beta-Hydroxybutyrate in Colorectal Cancer

DNA and Cell Biology, 2022
Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the United States. Although certain genetic predispositions may contribute to one's risk for developing CRC, dietary and lifestyle factors may play an important role as well.
Svetlana Khoziainova, Galina Rozenberg, Maayan Levy   +2 more
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Postmortem Distribution of 3‐Beta‐Hydroxybutyrate

Journal of Forensic Sciences, 2013
AbstractThe concentrations of 3‐beta‐hydroxybutyrate (3HB) in femoral blood, urine, vitreous humor as well as pericardial and cerebrospinal fluids were retrospectively examined in a series of medico‐legal autopsies, which included cases of diabetic ketoacidosis, hypothermia fatalities without ethanol in blood, bodies presenting mild decompositional ...
Cristian, Palmiere, Patrice, Mangin, Dominique, Werner   +2 more
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Association of Beta Hydroxybutyric Acidosis with Isoniazid Intoxication

Journal of Toxicology: Clinical Toxicology, 1984
Acute metabolic acidosis associated with accumulation of lactate has been previously reported in isoniazid (INH) intoxication. To our knowledge, association of INH toxicity with beta-hydroxybutyric acidosis has not been demonstrated previously. The present report documents the occurrence of beta-hydroxybutyric acidosis in patients with INH intoxication.
M V, Pahl, N D, Vaziri, R, Ness, R, Nathan, M, Maksy   +4 more
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Influence of beta-hydroxybutyrate on cultured mammalian cells

Experimental Cell Research, 1965
Abstract Accumulation of fat granules in cultured human liver cells and mouse fibroblasts was induced by β-hydroxybutyrate (BHB) at concentrations of 1 per cent or more. Metabolic effects concomitant with the ketone produced accumulation of fat granules included reduced DNA synthesis and glucose utilization.
W B, Savchuck, W L, Lockhart, M E, Merriman   +2 more
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Capillary beta-hydroxybutyrate determination for monitoring diabetic ketoacidosis

Endocrinología y Nutrición (English Edition), 2011
Diabetic ketoacidosis (DKA) is the most severe acute metabolic complication of type 1 diabetes mellitus. Insulin treatment is commonly guided by plasma glucose levels and changes in venous blood gases, while β-hydroxibutyrate (BHB) levels are rarely measured.
Beatriz, Rodríguez-Merchán, Ana, Casteràs, Eva, Domingo, Francisco José, Nóvoa, Yaiza, López, José Manuel, Cabezas-Agricola, Teresa, Rivero, Mónica, Parramón, Jordi, Mesa   +8 more
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UNRECOGNIZED PERSISTENCE OF BETA-HYDROXYBUTYRATE IN DIABETIC KETOACIDOSIS

Endocrine Research, 2001
We quantitated serial serum beta-hydroxybutyrate (beta-OHB) levels using the Ketosite method in 9 children with IDDM who were treated for diabetic ketoacidosis (DKA) and compared them to urinary ketone measurements by dipstick. Persistent elevations of serum beta-OHB were seen in six patients when the urine became clear of ketones; five of these ...
U M, Nadgir, F L, Silver, M H, MacGillivray   +2 more
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Beta-Hydroxybutyrate: A Supplemental Molecule for Various Diseases

Current Drug Targets
: β-hydroxybutyrate (BHB) is a ketone body that serves as an alternative energy source for various tissues, including the brain, heart, and skeletal muscle. As a metabolic intermediate and signaling molecule, BHB plays a crucial role in modulating cellular and physiological processes.
Navid Reza Shahtaghi, Bindu Soni, Hossamaldeen Bakrey, Samira Bigdelitabar, Subheet Kumar Jain   +4 more
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Modulation of beta-hydroxybutyrate in traumatic brain injury

Current Opinion in Clinical Nutrition & Metabolic Care
Purpose of review Traumatic brain injury (TBI) is a significant public health concern with substantial morbidity and mortality rates in the United States. Current management strategies primarily focus on symptomatic approaches and prevention of secondary complications.
Niraj, Arora, Dhaval Hitendrakumar, Shastri, Utsav Prakashbhai, Patel, Kunal, Bhatia   +3 more
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Biochemical basis for D,L,‐beta‐hydroxybutyrate‐induced teratogenesis

Teratology, 1990
AbstractPrevious investigations have demonstrated that a potential mechanism for D,L,‐beta‐hydroxybutyrate (BOHB)‐induced teratogenesis in neurulating mouse embryos (5–6 somite stage) after 24 hours of exposure in vitro is mediated by an inhibition of the pentose phosphate pathway (PPP) (Hunter, et al. '87). Employing conceptuses of an earlier stage (2–
L, Shum, T W, Sadler
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Beta-hydroxybutyric acid attenuates neuronal damage in epileptic mice

Acta Histochemica, 2019
β-Hydroxybutyric acid (BHBA) reportedly has neuroprotective and anti-oxidation properties. The present study aimed to investigate the protective effects of BHBA against epilepsy. C57BL/6 J mice were exposed to lithium chloride and pilocarpine to induce epilepsy and then were administrated with 300 mg/kg/day BHBA for 30 days. The learning impairment was
Qinghui, Guo, Shangming, Liu, Shandan, Wang, Meiyan, Wu, Zhaoxia, Li, Yibiao, Wang   +5 more
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