Results 151 to 160 of about 63,634 (227)

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama, Hikari Sada, Takeshi Nanjo   +2 more
wiley   +1 more source

Cycloaddition Reaction of Imines with Acid Chlorides in the Presence of a Tertiary Base: Variation of the Methods for the Synthesis of Beta Lactams

, 2017
Bimal Krishna Banik
openalex   +1 more source

A comprehensive review of cluster methods for drug–drug interaction network

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract The detection of drug–drug interaction (DDI) is crucial to the rational use of drug combinations. Experimentally, DDI detection is time‐consuming and laborious. Currently, researchers have developed a variety of computational methods to predict DDI.
Shuyuan Cao, Guixia Liu, Xiangrun Zhou, Ji Lv   +3 more
wiley   +1 more source

Beta-lactam dose reductions in critically ill patients with acute kidney injury: a scoping review. [PDF]

Crit Care
Horstink MMB, Rietdijk WJR, Geel DR, Deetman PE, Endeman H, Koch BCP, den Uil CA.   +6 more
europepmc   +1 more source

Studies on β-Lactam Antibiotics. VI. Structure of Degradation Products of Apalcillin Sodium

, 1980
Hisao Tobiki, N. HAMMA, Norihiko Tanno, Isao UMEDA   +3 more
openalex   +2 more sources

Effects of CwlM, a peptidoglycan synthesis regulator, on beta-lactam tolerance and host-pathogen interactions. [PDF]

BMC Microbiol
Silveiro C, Mortinho D, Olivença F, Mandal M, Pires D, Anes E, Catalão MJ.   +6 more
europepmc   +1 more source

Dual‐Mode Thio‐MacMillan Organocatalysts: Stereoselective Diels–Alder Reactions or Sacrificial Self‐Cyclization to N‐Bridged Bicyclic Lactams

Chemistry – A European Journal, Volume 32, Issue 5, 2 February 2026.
The study of the Diels–Alder reaction of cinnamaldehyde and cyclopentadiene, catalyzed by chiral imidazolidine‐4‐thiones, led to the discovery of a highly regio‐ and stereoselective Michael‐addition and consecutive ring closure. Here, the imidazolidine‐4‐thione not only catalytically activates cinnamaldehyde but also participates as the nucleophile to ...
Marian S. R. Ebeling, Luca V. Parziale, Marc Sachsenhauser, Christoph J. B. Seifert, Nathalie J. Kurrle, Oliver Trapp   +5 more
wiley   +1 more source

3‑Hydroxy-Beta-Lactam Inhibitors of Dihydrofolate Synthetase. [PDF]

ACS Bio Med Chem Au
Virgin-Downey B, Fang L, Nosal CR, Wencewicz TA.   +3 more
europepmc   +1 more source

Lysis of Escherichia coli by beta-lactams which bind penicillin-binding proteins 1a and 1b: inhibition by heat shock proteins

, 1991
Janellk . Powell, Kevin D. Young
openalex   +2 more sources

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

Animal Research and One Health, Volume 4, Issue 1, Page 82-93, February 2026.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao, Xingyuan Ma, Ping Tian, Lianbin Li, Zafir Muhammad, Xiaokun Wang, Xuemei Xue, Jinhe Xiao, Liangjun Zheng, F. A. El‐Gohary, Xin Zhao, Junning Pu, Huping Xue   +12 more
wiley   +1 more source