Results 191 to 200 of about 63,634 (227)

Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15‐Veratroyl‐17‐Acetyl‐19‐Oxodictizine, and the Proposed Structure of Acochlearine

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
An intramolecular Mannich reaction (A/B/E/F rings) and intermolecular Diels–Alder reactions (C/D rings) afforded a cage‐like hexacyclic core skeleton of denudatine alkaloids. Derivatization of the hexacyclic intermediate enabled the first asymmetric total syntheses of four denudatine alkaloids: (–)‐cochlearenine, (–)‐macrocentrine, (–)‐dictizine, and (–
Shun Kawano, Naoya Miyamoto, Kosuke Fujioka, Hiroki Toya, Juri Sakata, Hidetoshi Tokuyama   +5 more
wiley   +2 more sources

Perceived Knowledge and Confidence of Beta-Lactam Allergy Management Among Pharmacy Students on Advanced Pharmacy Practice Experiences. [PDF]

Pharmacy (Basel)
Wagner JL, Oliver DR, Jones BM, Stover KR, Watts MT, Kufel WD, McDowell L, McGee EU, Stevenson TL, Bland CM.   +9 more
europepmc   +1 more source

Susceptibility Assessment and Review of Novel Beta-Lactam/Beta-Lactamase Inhibitor against Carbapenem-Resistant Enterobacterales [PDF]

Sae Am Song
openalex   +1 more source

Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis

Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley   +1 more source

The penems, a new class of .BETA.-lactam antibiotics. 7. Synthesis and antimicrobial activity of 2-heterocyclylmercaptoalkyl derivatives.

, 1986
M. LANG, Peter Schneider, W. TOSCH, R. SCARTAZZINI, O. Zák   +4 more
openalex   +2 more sources

Correction to "Plasma Trough Concentrations of Beta-Lactam Antibiotics in the Early Phase of Septic Shock". [PDF]

Acta Anaesthesiol Scand
europepmc   +1 more source

A prospective cohort feasibility study of real-time beta-lactam antimicrobial therapeutic drug monitoring in critically ill patients with lower respiratory infection: The TDM-TIME study. [PDF]

J Intensive Care Soc
Hansel J, Lain J, Erhieyovwe EO, Ismayilli A, Orr J, Keevil BG, Ogungbenro K, Dark PM, Felton TW.   +8 more
europepmc   +1 more source

Once Allergic, Now Not: Do Children Use Delabeled Antibiotics?—A 5‐Year Follow‐Up Study

Acta Paediatrica, Volume 115, Issue 2, Page 491-492, February 2026.
Nikolaos Kitsos, Antigoni Mavroudi, Ioanna Grivea, Dimitrios Cassimos   +3 more
wiley   +1 more source

Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng, Belén Lucas, Philipp Lampe, Stefano Ugel, Suyuan Chen, Anke Unger, Matthias Bischoff, Soheila Rezaei Adariani, Kesava Reddy Naredla, Kamal Kumar, Annika Schmidt, Carsten Strohmann, Petra Janning, Raphael Gasper, María Lucas, Malte Gersch, Sonja Sievers, Vincenzo Bronte, Slava Ziegler, Herbert Waldmann   +19 more
wiley   +2 more sources

Evolution of beta-lactam resistance causes fitness reductions and several cases of collateral sensitivities in the human pathogen <i>Haemophilus influenzae</i>. [PDF]

Antimicrob Agents Chemother
Petersen S, Diricks M, Utpatel C, Schulenburg H, Merker M.   +4 more
europepmc   +1 more source