Results 41 to 50 of about 1,013,196 (143)

Comparison between a direct-flow SPR immunosensor for ampicillin and a competitive conventional amperometric device: analytical features and possible applications to real samples [PDF]

, 2017
In this research, we developed a direct-flow surface plasmon resonance (SPR) immunosensor for ampicillin to perform direct, simple, and fast measurements of this important antibiotic.
Campanella, Luigi, Favero, Gabriele, Martini, Elisabetta, Mazzei, Franco, Merola, Giovanni, Sanzo', Gabriella, Tomassetti, Mauro   +6 more
core   +2 more sources

Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes

PLoS Genetics, 2014
Traditional genetic association studies are very difficult in bacteria, as the generally limited recombination leads to large linked haplotype blocks, confounding the identification of causative variants.
C. Chewapreecha, P. Marttinen, N. Croucher, S. Salter, S. Harris, A. Mather, W. Hanage, D. Goldblatt, F. Nosten, C. Turner, P. Turner, S. Bentley, J. Parkhill   +12 more
semanticscholar   +1 more source

THERAPEUTIC DRUG MONITORING OF BETA-LACTAM ANTIBIOTICS IN CRITICALLY ILL PATIENTS WITH SEPSIS [PDF]

, 2021
Sepsis is a devastating diagnosis affecting over 750,000 patients a year, accounting for approximately 10% of all hospital admissions, costs more than $50,000 per patient, and exceeds $17 billion annual spending.
Thompson Bastin, Melissa
core   +1 more source

Beta-lactam dosing in critically ill patients with septic shock and continuous renal replacement therapy

Critical Care, 2014
Although early and appropriate antibiotic therapy remains the most important intervention for successful treatment of septic shock, data guiding optimization of beta-lactam prescription in critically ill patients prescribed with continuous renal ...
M. Ulldemolins, S. Vaquer, M. Llauradó-Serra, C. Pontes, G. Calvo, D. Soy, I. Martín-Loeches   +6 more
semanticscholar   +1 more source

Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]

, 2013
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown, Caron, Cars, Cars, Collignon, Dagan, DiNubile, Drlica, Essack, Fox, Geli, Goren, Gould, Guillemot, Harris, Hurdle, Huttner, Isha, Madurell, Masterton, Michalsen, Mitchison, Mitchison, Molstad, Sharma, Solapure, Talbot, Thomas   +27 more
core   +2 more sources

Beta lactam antibiotic monotherapy versus beta lactam-aminoglycoside antibiotic combination therapy for sepsis.

Cochrane Database of Systematic Reviews, 2014
BACKGROUND Optimal antibiotic treatment for sepsis is imperative. Combining a beta lactam antibiotic with an aminoglycoside antibiotic may provide certain advantages over beta lactam monotherapy.
M. Paul, A. Lador, S. Grozinsky-Glasberg, L. Leibovici   +3 more
semanticscholar   +1 more source

Structural basis for antibiotic transport and inhibition in PepT2 [PDF]

The uptake and elimination of beta-lactam antibiotics in the human body are facilitated by the proton-coupled peptide transporters PepT1 (SLC15A1) and PepT2 (SLC15A2).
Biggin, Philip C., Deme, Justin C., Kuteyi, Gabriel, Lea, Susan M., Lichtinger, Simon M., Newstead, Simon, Parker, Joanne L.   +6 more
core   +2 more sources

Beta lactam antibiotics residues in cow's milk: comparison of efficacy of three screening tests used in Bosnia and Herzegovina.

Bosnian Journal of Basic Medical Sciences, 2014
Beta lactam antibiotics are widely used in therapy of cattle, particularly for the treatment of mastitis.  Over 95% of residue testing in dairies in Bosnia and Herzegovina is for Beta lactams.
N. Fejzic, Muris Begagić, S. Šerić-Haračić, M. Smajlovic   +3 more
semanticscholar   +1 more source

The Relationship between Antimicrobial Use and Antimicrobial Resistance in Europe [PDF]

, 2002
In Europe, antimicrobial resistance has been monitored since 1998 by the European Antimicrobial Resistance Surveillance System (EARSS). We examined the relationship between penicillin nonsusceptibility of invasive isolates of Streptococcus pneumoniae (an
Arason, Austin, Branthwaite, Buchholz, Cars, Commissie Richtlijnen Gevoeligheidsbepalingen, Contopoulos-Ionnides, Deeks, Deutsches Institut für Normung, Fridkin, Goettsch, Goettsch, González, Irene K. Veldhuijzen, Jacob L. Kool, John E. Degener, Kristinsson, Lyytikainen, Marc J.W. Sprenger, Melander, Mouton, Mölstad, Nava, Otto Cars, Seppala, Sigvard Mölstad, Stef L.A.M. Bronzwaer, Stephenson, Tan, Udo Buchholz, Wim Goettsch   +30 more
core   +2 more sources

Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropenia.

Cochrane Database of Systematic Reviews, 2013
BACKGROUND Continued controversy surrounds the optimal empirical treatment for febrile neutropenia. New broad-spectrum beta-lactams have been introduced as single treatment, and classically, a combination of a beta-lactam with an aminoglycoside has been ...
M. Paul, Y. Dickstein, Agata Schlesinger, S. Grozinsky-Glasberg, K. Soares-Weiser, L. Leibovici   +5 more
semanticscholar   +1 more source