Beta-lactams are commonly used antibiotics that prevent cell-wall biosynthesis. Beta-lactam sensitive bacteria can acquire conjugative resistance elements and hence become resistant even after being exposed to lethal (above minimum inhibitory) antibiotic
Given, Cindy +7 more
core +1 more source
Progression of ampC amplification during de novo amoxicillin resistance development in E. coli
Beta-lactam antibiotics are the most applied antimicrobials in human and veterinarian health care. Hence, beta-lactam resistance is a major health problem.
Luyuan Nong +4 more
doaj +1 more source
Progressive Sub-MIC Exposure of Klebsiella pneumoniae 43816 to Cephalothin Induces the Evolution of Beta-Lactam Resistance without Acquisition of Beta-Lactamase Genes. [PDF]
Anderson JR +8 more
europepmc +1 more source
Pneumococcus morphogenesis and resistance to beta-lactams
Morphogenèse du pneumocoque et résistance aux bêta-lactamines Streptococcus pneumoniae, le pneumocoque, est une bactérie pathogène qui entraîne le décès de plus d'un million et demi de personnes dans le monde chaque année. Les β-lactamines sont très utilisées pour traiter les infections à pneumocoques.
openaire +2 more sources
CRISPRi-mediated characterization of novel anti-tuberculosis targets: Mycobacterial peptidoglycan modifications promote beta-lactam resistance and intracellular survival. [PDF]
Silveiro C +8 more
europepmc +1 more source
Beta-Lactam Resistance in Enterobacterales
openaire +1 more source
Carbapenems are the antibiotics of choice for treating multidrug-resistant bacterial infections. Metallo-β-lactamases (MBLs) are carbapenemases capable of hydrolyzing nearly all therapeutically available beta-lactam antibiotics.
Mamun Al Asad +8 more
core +1 more source
Characterization of YdgH: a mediator of beta-lactam susceptibility in Enterobacterales
Beta-lactam antibiotics are often the treatment of choice for serious bacterial infections. In a previous screen for novel genetic mediators affecting beta-lactam susceptibility, we discovered that deletion of ydgH, a conserved gene of unknown function ...
Jacob E. Lazarus +2 more
doaj +1 more source
Does plasmid-based beta-lactam resistance increase E. coli infections: Modelling addition and replacement mechanisms. [PDF]
Godijk NG +6 more
europepmc +1 more source
ß-Lactam-ß-lactamase Inhibitor Combination against ESBL-Producing Enterobacteriaceae
In the last decades, Extended-Spectrum-β-Lactamases (ESBLs) in gram negative bacilli have appeared as a significant mechanism of resistance to antibiotics. Although resistance to carbapenems is increasing among bacteria, they are still the treatment
A Hashemi
doaj

