Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos +11 more
wiley +1 more source
Promising Future of Novel Beta-Lactam Antibiotics Against Bacterial Resistance
Saeed M Tayeb,1 Jaser A Alharbi,1 Bushra B Alattas,1 Dana M Alotaibi,1 Nawaf M Althibaiti,1 Jaser F Alharbi,1 Ahmad E SafirAldeen,1 Ibrahim R Alqurashi,1 Saad M Wali2 1Pharmaceutical Sciences Department, College of Pharmacy, Umm Al-Qura University ...
Tayeb SM +8 more
doaj
Progression of ampC amplification during de novo amoxicillin resistance development in E. coli
Beta-lactam antibiotics are the most applied antimicrobials in human and veterinarian health care. Hence, beta-lactam resistance is a major health problem.
Luyuan Nong +4 more
doaj +1 more source
Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative
Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial stewardship ...
Claire E. Ciarkowski +6 more
wiley +1 more source
Progressive Sub-MIC Exposure of Klebsiella pneumoniae 43816 to Cephalothin Induces the Evolution of Beta-Lactam Resistance without Acquisition of Beta-Lactamase Genes. [PDF]
Anderson JR +8 more
europepmc +1 more source
Beta-Lactam Resistance: Clinical Implications for Pediatric Patients
The emergence of resistance to established antibiotic agents such as beta-lactams has been reported worldwide and poses a serious challenge to the management of pediatric infections. The most common mechanism of resistance involves the production of an enzyme that inactivates the antibiotic before it can be effective. Streptococcus pneumoniae, the most
openaire +2 more sources
CRISPRi-mediated characterization of novel anti-tuberculosis targets: Mycobacterial peptidoglycan modifications promote beta-lactam resistance and intracellular survival. [PDF]
Silveiro C +8 more
europepmc +1 more source
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira +3 more
wiley +1 more source
In Vitro Selection of High-Level Beta-Lactam Resistance in Methicillin-Susceptible Staphylococcus aureus. [PDF]
Gostev V +6 more
europepmc +1 more source
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge +5 more
wiley +1 more source

