Results 101 to 110 of about 78,679 (204)

[Bacterial resistance against beta-lactam antibiotics].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1991
Beta-lactam antibiotics include the penicillins, cephalosporins, oxacephems (moxalactam), carbapenems (imipenem) and monobactams (azthreonam)--all with a common beta-lactam ring. Beta-lactam antibiotics block the synthesis and growth of the bacterial cell wall by binding to penicillin-binding proteins on the cytoplasma membrane. The bacteria may escape
openaire   +1 more source

Characterization of YdgH: a mediator of beta-lactam susceptibility in Enterobacterales

open access: yesMicrobiology Spectrum
Beta-lactam antibiotics are often the treatment of choice for serious bacterial infections. In a previous screen for novel genetic mediators affecting beta-lactam susceptibility, we discovered that deletion of ydgH, a conserved gene of unknown function ...
Jacob E. Lazarus   +2 more
doaj   +1 more source

ß-Lactam-ß-lactamase Inhibitor Combination against ESBL-Producing Enterobacteriaceae

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2016
In the last decades, Extended-Spectrum-β-Lactamases (ESBLs) in gram negative bacilli have appeared as a significant mechanism of resistance to antibiotics. Although resistance to carbapenems is increasing among bacteria, they are still the treatment
A Hashemi
doaj  

Resolved genomes of wastewater ESBL-producing Escherichia coli and metagenomic analysis of source wastewater samples

open access: yesMicrobiology Spectrum
Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli pose a serious threat to human health because of their resistance to the most commonly prescribed antibiotics: penicillins and cephalosporins.
Clinton Cheney   +7 more
doaj   +1 more source

Target Fidelity and Failure: Structure–Activity Relationship of High-Molecular-Mass Penicillin-Binding Proteins (HMM-PBPs) in Refractory Granulicatella adiacens Endocarditis

open access: yesAntibiotics
Background/Objectives: Granulicatella adiacens infective endocarditis is conventionally managed with penicillin, ampicillin, or ceftriaxone in combination with gentamicin, although double beta-lactam regiments have been proposed a safer alternative to ...
Paola Conti   +8 more
doaj   +1 more source

Prediction of antimicrobial susceptibility of pneumococci based on whole-genome sequencing data: a direct comparison of two genomic tools to conventional antimicrobial susceptibility testing

open access: yesJournal of Clinical Microbiology
Determination of antimicrobial resistance (AMR) in pneumococcal isolates is important for surveillance purposes and in a clinical context. Antimicrobial susceptibility testing (AST) of pneumococci is complicated by the need for exact minimal inhibitory ...
Gerardo J. Sanchez   +5 more
doaj   +1 more source

Beta-Lactam Resistance in Enterobacterales

open access: yesGastroenterology: Medicine & Research, 2022
openaire   +1 more source

Impact of beta-lactam allergy labels on bone marrow transplant patients

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: Approximately 95% of patients with a beta-lactam allergy noted in their medical record are not truly allergic when tested. These patients may unnecessarily avoid first-line antibiotics, resulting in increased treatment failure, higher costs ...
Benjamin M. Haxby   +5 more
doaj   +1 more source

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