Journal of Infection and Public Health, 2018 Purposes: The objective of the study was to identify the trends and relations between antimicrobial resistance (AMR) and antibiotic use in the Xinjiang Uyghur Autonomous Region in Western China from 2014 to 2016.
Haishaerjiang Wushouer +6 more
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The mechanism of heterogeneous beta-lactam resistance in MRSA: key role of the stringent stress response. [PDF]
PLoS ONE, 2013 All methicillin resistant S. aureus (MRSA) strains carry an acquired genetic determinant--mecA or mecC--which encode for a low affinity penicillin binding protein -PBP2A or PBP2A'--that can continue the catalysis of peptidoglycan transpeptidation in the ...
Choonkeun Kim +5 more
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Multiparametric determination of genes and their point mutations for identification of beta-lactamases [PDF]
, 2010 More than half of all currently used antibiotics belong to the beta-lactam group, but their clinical effectiveness is severely limited by antibiotic resistance of microorganisms that are the causative agents of infectious diseases. Several mechanisms for
A. A. Medeiros +127 more
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Constitutively vancomycin-resistant Enterococcus faecium resistant to synergistic beta-lactam combinations [PDF]
Antimicrobial Agents and Chemotherapy, 1993 Vancomycin resistance among enterococci has recently been recognized. Synergy between vancomycin and penicillin has been shown in vitro for isolates of Enterococcus faecium resistant to both of these antibiotics. We describe three isolates of vancomycin-resistant E. faecium which demonstrate unique phenotypic characteristics.
M, Green +6 more
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Zagazig Journal of Pharmaceutical Sciences, 2016 This study aimed for the molecular detection of TEM and SHV genes in Extended-Spectrum beta-lactamases (ESBLs) clinical isolates of Enterobacteriace (Eshericichia coli, Klebsiella pneumoniae and Proteus spp.).
Ashraf Kadry +2 more
doaj +1 more source
Functional Characterization of Bacteria Isolated from Ancient Arctic Soil Exposes Diverse Resistance Mechanisms to Modern Antibiotics [PDF]
, 2013 Using functional metagenomics to study the resistomes of bacterial communities isolated from different layers of the Canadian high Arctic permafrost, we show that microbial communities harbored diverse resistance mechanisms at least 5,000 years ago ...
Dantas, Gautam +5 more
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Resistance of Pseudomonas aeruginosa to new beta-lactamase-resistant beta-lactams [PDF]
Antimicrobial Agents and Chemotherapy, 1984 An isogenic set of mutants of Pseudomonas aeruginosa, altered in permeability or permeability plus constitutive production of beta-lactamase, was examined for susceptibility to newer beta-lactam antibiotics. Kinetic data on the chromosomal beta-lactamase and susceptibility studies for the test beta-lactams indicate that permeability was the major ...
A J, Godfrey, L E, Bryan
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Identification of drivers of mycobacterial resistance to peptidoglycan synthesis inhibitors
Frontiers in Microbiology, 2022 Beta-lactams have been excluded from tuberculosis therapy due to the intrinsic resistance of Mycobacterium tuberculosis (Mtb) to this antibiotic class, usually attributed to a potent beta-lactamase, BlaC, and to an unusually complex cell wall.
Francisco Olivença +8 more
doaj +1 more source
Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics. [PDF]
, 2019 Endovascular infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a major health care concern, especially infective endocarditis (IE).
Abdelhady, Wessam +5 more
core
2-Octylcyclopentanone Inhibits Beta Lactam Resistant Diabetic Wound Pathogens
Tropical Life Sciences Research, 2023 Microbial infection is a frequent complication of diabetic foot ulcers, with up to 82% of ulcers being infected at the initial stage of diabetes. Furthermore, the emergence of beta lactam resistant pathogens managed to eliminate the use of beta lactam antibiotics as a chemotherapeutic alternative.
Nur Amiera Syuhada Rozman +5 more
openaire +2 more sources