Detection of extended spectrum B-lactamases in urinary isolates of Klebsiella pneumoniae in relation to Bla SHV, Bla TEM and Bla CTX-M gene carriage [PDF]
, 2011 Background: Resistance to contemporary broad-spectrum β-lactam antibiotics mediated by extended-spectrum β-lactamases (ESBLs) is increasing worldwide.
Eftekhar, F. +3 more
core +1 more source
Resistome flow in global landfill systems
iMetaOmics, EarlyView.Global landfill systems represent key hubs of resistome, serving as dynamic reservoirs and amplifiers through plasmid‐driven gene mobility. Waste flows and environmental pathways sustain the transboundary resistome networks, accelerating resistance dissemination across ecosystems.
Wenqing Hong +12 more
wiley +1 more source
New boronate drugs and evolving NDM-mediated beta-lactam resistance. [PDF]
Antimicrob Agents Chemother, 2023 Lomovskaya O +5 more
europepmc +1 more source
Empiric Antibiotic Therapy in the Treatment of Community-acquired Pneumonia in a General Hospital in Saudi Arabia [PDF]
, 2019 Background: Guideline-based empiric antimicrobial therapy is recommended for the treatment of community-acquired pneumonia (CAP). In this study, we evaluate the pattern of empiric antibiotics of CAP patients.
Al-Tawfiq, Jaffar A. +2 more
core +1 more source
Journal of Biophotonics, EarlyView.Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa +3 more
wiley +1 more source
In host evolution of beta lactam resistance during active treatment for Pseudomonas aeruginosa bacteremia. [PDF]
Front Cell Infect Microbiol, 2023 Spottiswoode N +11 more
europepmc +1 more source
Results of A Local Combination Therapy Antibiogram For \u3cem\u3ePseudomonas Aeruginosa\u3c/em\u3e Isolates: Is Double Worth The Trouble? [PDF]
, 2017 Purpose: To determine the frequency at which fluoroquinolones and aminoglycosides demonstrate in vitro activity against non-urinary, non-skin/skin structure Pseudomonas aeruginosa isolates exhibiting decreased susceptibilities to one or more β-lactam ...
Davis, Jim +4 more
core +1 more source
Social interactions in the Burkholderia cepacia complex : biofilms and quorum sensing [PDF]
, 2010 Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B.
Coenye, Tom
core +2 more sources
Journal of Clinical Laboratory Analysis, EarlyView.A novel hexaplex recombinase polymerase amplification (RPA) method was developed to rapidly and accurately detect five key carbapenemase genes and a Klebsiella pneumoniae‐specific target in a single reaction. This makes it an effective tool for CRKP detection in resource‐constrained environments.
Suthawan Mutitanon +1 more
wiley +1 more source
Restrictive antibiotic stewardship associated with reduced hospital mortality in gram-negative infection [PDF]
, 2017 Introduction: Antimicrobial stewardship has an important role in the control of Clostridium difficile infection (CDI) and antibiotic resistance. An important component of UK stewardship interventions is the restriction of broad-spectrum beta-lactam ...
Helps, Alieen +5 more
core +1 more source