Results 101 to 110 of about 52,329 (268)

Indirect Method for Assessing the Penetration of Beta-Lactamase-Nonsusceptible Penicillins and Cephalosporins in Escherichia coli Strains [PDF]

, 1976
M. H. Richmond, D. C. Clark, S. F. Wotton   +2 more
openalex   +1 more source

Studies Concerned with the Structure and Synthesis of the Anti‐viral Tropolone Glycoside Liriosmaside A

ChemistryOpen, EarlyView.
The core of the anti‐viral troponoid natural product liriosmaside A lacking the 3‐hydroxy‐3‐methylglutaric acid (HMGA) side‐chain at C6′ has been prepared. The early steps involved the gem‐dibromocyclopropane‐mediated ring‐expansion of a readily‐obtained Robinson annulation product.
Qi Chen, Yaping Zhan, Michael G. Gardiner, Zeinab G. Khalil, Amila A. Dewa, Thulasi Sritharan, Robert J. Capon, Ping Lan, Shen Tan, Martin G. Banwell   +9 more
wiley   +1 more source

Pharmacokinetics of continuous infusion ceftolozane/tazobactam in two patients with extensive total body surface area burns

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Introduction Treatment of infections in patients with burn injuries is challenging due to altered antimicrobial pharmacokinetics. Continuous infusion β‐lactam therapy may be a useful antimicrobial stewardship strategy to improve pharmacodynamic target attainment in this population.
Jay D. Olivet, Megan Amerson‐Brown, Juan J. Calix, Emma Graffice, Tyson Kilpatrick, Hanna F. Roenfanz, David P. Nicolau, Joseph L. Kuti, Matthew L. Brown   +8 more
wiley   +1 more source

Cefaclor: In Vitro Spectrum of Activity and Beta-Lactamase Stability [PDF]

, 1978
Harold C. Neu, Kwung P. Fu
openalex   +1 more source

Frequency of IMP-1 and VIM Genes among Metallo-beta-Lactamase Producing Acinetobacter spp. Isolated from Health Care Associated Infections inNortheast of Iran

Journal of Medical Bacteriology, 2015
Background: The emergence and rapid spread of metallo-beta-lactamase (MBL) producing Acinetobacter spp. are of great concern worldwide due to limited treatment options. Epidemiologic studies of the causing genes are important for prevention. Methods:  In
Neda Noori, Jalil Vandyosefi, Faeze Sabet, Sara Ashrafi, Kiarash Ghazvini   +4 more
doaj  

Polymeric Anti‐Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution

Small, EarlyView.
This study introduces sevelamer (SEV) microparticles as a repurposed adjuvant therapy to combat antimicrobial resistance. SEV microparticles effectively capture vancomycin (VAN) and daptomycin (DAP), preventing these last‐resort antibiotics from driving resistance.
Roya Koshani, Shang‐Lin Yeh, Zeming He, Naveen Narasimhalu, Landon G. vom Steeg, Derek G. Sim, Robert J. Woods, Andrew F. Read, Amir Sheikhi   +8 more
wiley   +1 more source

Right Once for All: Inflammation‐Targeted Zinc–Cobalt Metal–Organic Framework Nanozymes with High Stability and Broad‐Spectrum Synergistic Antibacterial Properties for Accelerating Bacteria‐Infected Wound Healing under Physiological Conditions

Small Structures, EarlyView.
Synergistic antibacterial nanoparticles (ZCMCC) composed of zinc‐cobalt metal‐organic frameworks (ZCM) loaded with chlorogenic acid (CGA) and modified with chitosan (CS) were developed. ZCMCC exhibited enhanced stability under physiological conditions, generated reactive oxygen species (ROS) via chemo‐dynamic therapy (CDT), and released CGA, achieving >
Xianchun Fu, Han Zhang, Zhi Liu, Li Yu, Yongtao Zhang, Changyao Wang   +5 more
wiley   +1 more source

Beta-Lactamases: Determination of Their Isoelectric Points [PDF]

, 1978
Michel Barthélémy, M. Guionie, Roger Labia   +2 more
openalex   +1 more source

Hybrid nanosystems for the treatment of infectious diseases produced by multidrug‐resistant bacteria: A systematic review

VIEW, EarlyView.
Abstract The rise of multidrug‐resistant (MDR) bacteria poses a significant challenge to effectively treating infectious diseases. In recent years, nanotechnology has emerged as a promising approach to combat MDR bacterial infections. This systematic review, following the research guidelines proposed by PRISMA, aims to provide a comprehensive overview ...
Pegah Tabatabaei Tabrizi, Jose M. Lanao, Carmen Gutierrez‐Millan, Clara I. Colino   +3 more
wiley   +1 more source

Production and Property of Beta-Lactamases in Streptomyces : Comparison of the Strains Isolated Newly and Thirty Years Ago [PDF]

, 1978
Hiroshi Ogawara, Susumu Horikawa, Sachiko Shimada-Miyoshi, Koji Yasuzawa   +3 more
openalex   +1 more source