Results 81 to 90 of about 52,329 (268)

Prevalence of β-Lactamase Production among Pathogenic Bacteria Isolated from Surgical Site and Wound Infection amoung Patients Admitted in some selected Hospitals in Sokoto Metropolis, Nigeria

International Journal of Environment, 2014
Antimicrobial resistance among pathogenic bacteria is increasing worldwide especially against ß-lactam drugs, due to the production of ß-lactamase enzymes which destroy the ß-lactam ring of these antibiotics, thus preventing the action ...
UK Muhammad, TM Adamu, Z Binji, MA Isa
doaj   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

The β-lactamase inhibitor avibactam (NXL104) does not induce ampC β -lactamase in Enterobacter cloacae

Infection and Drug Resistance, 2013
Christine Miossec, Monique Claudon, Premavathy Levasseur, Michael T Black Novexel, Romainville, France Abstract: Induction of ampC β-lactamase expression can often compromise antibiotic treatment and is triggered by several β-lactams (such as ...
Miossec C, Claudon M, Levasseur P, Black MT   +3 more
doaj  

Antimicrobial Susceptibility Profile of Eggerthella lenta Isolated From Bloodstream and Abdominal Fluid Infections

iLABMED, EarlyView.
Antimicrobial susceptibility analysis of clinical Eggerthella lenta isolates. This study reviewed 36 E. lenta isolates from the bloodstream and abdominal fluids (2018–2024). Identification methods included VITEK 2 ANC, MALDI‐TOF, and 16S rRNA sequencing. Antimicrobial susceptibility testing using agar dilution followed CLSI and EUCAST guidelines.
Yuan Gao, Longfeng Qu, Shu Zhang, Cheng Cheng, Bin Tang   +4 more
wiley   +1 more source

Selective expansion of gut antibiotic resistome and underlying pathways involved in type 1 diabetes

iMetaOmics, EarlyView.
Selective expansion of gut antibiotic resistance genes (including glycopeptides, tetracyclines, macrolide‐lincosamide‐streptogramins, and beta‐lactams) was observed in type 1 diabetic rats. Interestingly, a similar expansion of gut antibiotic resistome occurred in diabetic patients.
Guozhu Ye, Yifang Duan, Haining Huang, Guoyou Chen, Minghui Li, Ricardo David Avellán‐Llaguno, Qiansheng Huang   +6 more
wiley   +1 more source

Investigation on Klebsiella pneumoniae in the field of extracellular vesicles

Interdisciplinary Medicine, EarlyView.
The role of extracellular vesicles in the pathogenicity and antibiotic resistance, as well as treatment and prevention of Klebsiella pneumoniae. Abstract Klebsiella pneumoniae (KP), recognized for its pronounced antibiotic resistance, is a prevalent agent of nosocomial infections such as hospital‐acquired pneumonia.
Junwei Wu, Yuheng Liu, Jin Su, Yi Yang, Haiyi Deng, Yilin Yang, Mengxi Yanglan, Xinyi Wu, Shiqi Luo, Yao Liao, Lifu Wang   +10 more
wiley   +1 more source

Some Properties of the Beta-Lactamase Genes in Staphylococcus epidermidis [PDF]

, 1969
Jack N. Baldwin, Robert H. Strickland, Marilyn F. Cox   +2 more
openalex   +1 more source

First report of NDM-1-producing Pseudomonas aeruginosa in Egypt

International Journal of Infectious Diseases, 2014
This work reports the occurrence of New Delhi metallo-beta-lactamase 1 (NDM-1) in metallo-beta-lactamase-producing Pseudomonas aeruginosa in Egypt for the first time, and the presence of more than one blaMBL gene in carbapenem-resistant P. aeruginosa.
Mai Mahmoud Zafer, Mady Amin, Hadir El Mahallawy, Mohammed Seif El-Din Ashour, Mohamed Al Agamy   +4 more
doaj   +1 more source

A Review of In Silico and In Vitro Approaches in the Fight Against Carbapenem‐Resistant Enterobacterales

Journal of Clinical Laboratory Analysis, EarlyView.
This review highlights computational approaches for discovering antimicrobials against carbapenem‐resistant Enterobacterales. It outlines methods like pharmacophore modeling, molecular docking, and absorption, distribution, metabolism, and excretion–toxicity (ADMET) analysis, integrated with in vitro assays, to identify and validate potential drugs ...
Muhammad Absar, Abdul Rahman Zaidah, Amer Mahmood, Sajjad Ahmad, Hasan Ejaz, Naveed Ahmed, Nik Haszroel Hysham Nik Hashim, Chan Yean Yean   +7 more
wiley   +1 more source

Anaerobies et beta-lactamases

Médecine et Maladies Infectieuses, 1989
Resume Les anaerobies produisent des beta-lactamases. La resistance aux beta-lactamines de Bacteroides fragilis est liee a la presence de beta-lactamases, il s'agit d'une cephalosporinase essentiellement. Des enzymes inactivant cefoxitine et imipeneme ont ete trouvees.
M. Derriennic, A Sedallian, J.P. Bru, L. Dubreuil   +3 more
openaire   +2 more sources