Results 81 to 90 of about 1,103,793 (328)
Clinical Pharmacology &Therapeutics, EarlyView.This manuscript describes the scope of implementation and impact of a regulatory agency‐qualified panel of six urine biomarkers on drug development, the process for which was conducted and funded by the Critical Path Institute, the Foundation for the National Institutes of Health, and the United States Food and Drug Administration.
Tanja S. Zabka +7 more
wiley +1 more source
Metallo-β-Lactamase and Extended-Spectrum-β-Lactamase Production by Serratia Strains [Letter]
Infection and Drug Resistance, 2020 Bhoj R Singh, 1 Shiv Varan Singh 2 1Division of Epidemiology, ICAR-Indian Veterinary Research Institute, Izatnagar 243122, India; 2Division of Bacteriology and Mycology, ICAR-Indian Veterinary Research Institute, Izatnagar 243122, IndiaCorrespondence ...
Singh BR, Singh SV
doaj
Environmental and Molecular Mutagenesis, EarlyView.Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal +14 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood +6 more
wiley +1 more source
Production of β-Lactamase Inhibitors by Streptomyces Species
Antibiotics, 2018 β-Lactamase inhibitors have emerged as an effective alternative to reduce the effects of resistance against β-lactam antibiotics. The Streptomyces genus is known for being an exceptional natural source of antimicrobials and β-lactamase ...
Daniela de Araújo Viana Marques +5 more
doaj +1 more source
Repurposing of Meropenem and Nadifloxacin for Treatment of Burn Patients? [PDF]
, 2009 The escalating number of multidrug resistant pathogens has demanded the swift development of new and potent antibiotics (ref. 2). Metallo-[beta]-lactamases (MBLs) continue to evolve, rendering the latest generation of carbapenem antibiotics useless (ref.
Christie E. Costa +5 more
core +1 more source
Draft Genome Sequence of Mycobacterium obuense Strain UC1, Isolated from Patient Sputum. [PDF]
, 2015 We report the draft genome sequence of Mycobacterium obuense strain UC1 from a patient sputum sample. This is the first draft genome sequence of Mycobacterium obuense, a rapidly growing scotochromogenic ...
Chiu, Charles Y +5 more
core +2 more sources
Medical Science Monitor, 2012 Summary Background Matrix-Assisted Laser-Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) has already proven to be a powerful tool for species identification in microbiological laboratories.
Reiner Schaumann +8 more
semanticscholar +1 more source
Food Frontiers, EarlyView.Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh +11 more
wiley +1 more source
Medicare Part D and Hospital Admissions due to Antimicrobial Resistance
Health Economics, EarlyView.ABSTRACT Antimicrobial resistance (AMR) has been increasing rapidly in the United States despite government efforts to contain its spread. Both under‐utilization and overuse of prescribed antimicrobials contribute to rising resistance. The introduction of Medicare Part D in 2006 expanded prescription drug coverage for the elderly, including coverage ...
Ricardo B. Ang III
wiley +1 more source