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Allergic Reactions and Cross-Reactivity Potential with Beta-Lactamase Inhibitors [PDF]

open access: yesPharmacy, 2019
Although beta-lactam allergies are an emerging focus of stewardship programs and interventions, less is publicly released regarding allergies to beta-lactamase inhibitors. This review presents and evaluates the data regarding allergic reactions with beta-
Kayla R. Stover   +2 more
doaj   +3 more sources

Breakthrough Advances in Beta-Lactamase Inhibitors: New Synthesized Compounds and Mechanisms of Action Against Drug-Resistant Bacteria [PDF]

open access: yesPharmaceuticals
Beta-lactam drugs hold a central place in the antibacterial arsenal, and the production of beta-lactamases by drug-resistant bacteria has severely compromised the effectiveness of nearly all available beta-lactams.
Ya-Si Huang, Hong Zhou
doaj   +3 more sources

Inverse association between use of broad spectrum penicllin with beta-lactamase inhibitors and prevalence of type 1 diabetes mellitus in Europe [PDF]

open access: yesScientific Reports, 2021
Increasing incidence of type 1 diabetes is supposed to be induced by environmental factors. Microbiome modulated by antibiotics seems to serve as one of the environmental factors which could influence the development of T1DM.
Gábor Ternák   +6 more
doaj   +2 more sources

Sporadic cefiderocol resistance in Escherichia coli from the United Arab Emirates involves multifactorial mechanisms reversible by novel beta-lactamase inhibitors [PDF]

open access: yesScientific Reports
Cefiderocol (CFDC), a novel siderophore-cephalosporin, is effective against multidrug-resistant (MDR) pathogens, but the emergence of resistance threatens its future use in treating infections.
Farah Al-Marzooq   +10 more
doaj   +2 more sources

Promising Future of Novel Beta-Lactam Antibiotics Against Bacterial Resistance [PDF]

open access: yesDrug Design, Development and Therapy
Saeed M Tayeb,1 Jaser A Alharbi,1 Bushra B Alattas,1 Dana M Alotaibi,1 Nawaf M Althibaiti,1 Jaser F Alharbi,1 Ahmad E SafirAldeen,1 Ibrahim R Alqurashi,1 Saad M Wali2 1Pharmaceutical Sciences Department, College of Pharmacy, Umm Al-Qura University ...
Tayeb SM   +8 more
doaj   +2 more sources

Metallo-beta-lactamase inhibitor phosphonamidate monoesters

open access: green, 2021
NMR raw data (FIDs) and processed spectra of the synthesized ...
Palica, Katarzyna   +6 more
openaire   +3 more sources

Correlation Between Antimicrobial Consumption and Resistance in Klebsiella pneumoniae During the COVID-19 Pandemic Using Dynamic Regression Models: A Quasi-Experimental Epidemiological Time-Series Study [PDF]

open access: yesAntibiotics
Background/Objectives: The COVID-19 pandemic has been reported to impact antimicrobial consumption (AMC) and antimicrobial resistance (AMR) worldwide. We aimed to assess this correlation in Klebsiella pneumoniae before and during the COVID-19 pandemic ...
Paul Laffont-Lozes   +6 more
doaj   +2 more sources

Diketene analogs as .BETA.-lactamase inhibitor.

open access: bronzeChemical and Pharmaceutical Bulletin, 1989
Compounds having a structural analogy with diketene have been synthesized and their potencies as beta-lactamase inhibitors have been studied. Among six compounds so far tested, alpha-phenyl-beta-benzylidene-3-propanolide was shown to be an irreversible inhibitor of the enzyme. The availability of simple monocyclic compounds as beta-lactamase inhibitors
K, Tanizawa, K, Santoh, Y, Kanaoka
openaire   +4 more sources

Various Extracts of Some Medicinal Plants as Inhibitors for Beta-lactamase Activity

open access: goldمجلة بغداد للعلوم, 2021
The inhibitory effect of acetone, ethanol, and aqueous extracts of ten medicinal plants on β-lactamase from Staphylococcus sciuri and Klebsiella pneumoniae was investigated in vitro by starch-iodine agar plate method.
Huda S. A. Al-Hayanni, Hamed El-Shora
doaj   +2 more sources

A multiscale approach to predict the binding mode of metallo beta-lactamase inhibitors. [PDF]

open access: hybridProteins, 2022
Gervasoni S   +6 more
europepmc   +2 more sources

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