Results 131 to 140 of about 1,753,858 (323)

Metallo-beta-lactamases: a last frontier for beta-lactams?

, 2011
Metallo-beta-lactamases are resistance determinants of increasing clinical relevance in Gram-negative bacteria. Because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all ...
Giamarellou, Helen, Cornaglia, Giuseppe, Rossolini, Gian Maria   +2 more
core  

Development of a set of multiplex PCR assays for the detection of genes encoding important beta-lactamases in Enterobacteriaceae.

Journal of Antimicrobial Chemotherapy, 2010
Caroline Dallenne, Anaelle Da Costa, D. Decré, C. Favier, G. Arlet   +4 more
semanticscholar   +1 more source

Serious Bacterial Infections in Hospitalized Neonates in Eastern Ethiopia: Investigating the Emerging Pathogen Pantoea dispersa Compared With Klebsiella pneumoniae

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Serious bacterial infections (SBIs) are major contributors to neonatal morbidity and mortality in low‐income countries. We describe the aetiology and risk factors for neonatal bacteraemia and in‐hospital mortality in eastern Ethiopia, focusing on Pantoea dispersa, a rarely studied pathogen, and Klebsiella pneumoniae.
Yunus Edris, Faisel A. Hassen, Desalegn A. Ayana, Fami Ahmed, Haleluya Leulseged, Dadi Marami, Jabir Aliye, Belete G. Alem, Zelalem T. Mariam, Gezahang Mengesha, Nega Assefa, Alexander M. Aiken, J. Anthony G. Scott, Lola Madrid   +13 more
wiley   +1 more source

beta-Lactamases in laboratory and clinical resistance

Clinical Microbiology Reviews, 1995
D. Livermore
semanticscholar   +1 more source

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

BJU International, Volume 138, Issue 1, Page 33-44, July 2026.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon, Asaad Ahmad, Natalie Lott, Alison Blatt   +3 more
wiley   +1 more source

Cloning and characterization of the endogenous cephalosporinase gene, cepA, from Bacteroides fragilis reveals a new subgroup of Ambler class A beta-lactamases.

, 2023
Bacteroides frgiglis CS30 is a clinical isolate resistant to high concentrations of benzylpenicillin and cephaloridine but not to cephamycin or penem antibiotics.
Smith, C. Jeffrey, NC DOCKS at East Carolina University, Parker, Anita C., Rogers, Marc B.   +3 more
core  

Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli, Volker Müller, Christoph Welsch, Heiko Mühl, Jonel Trebicka, Volkhard A. J. Kempf   +5 more
wiley   +1 more source

Metallo-beta-lactamases and their biomimetic complexes

, 2014
In order to treat bacterial infections successfully in the future, the mechanism of action of metallo-beta-lactamases (M beta Ls) needs to be fully understood so that clinically useful inhibitors and new therapeutic approaches can be developed.
Schenk, Gerhard, Daumann, Lena J., Gahan, Lawrence R.   +2 more
core   +1 more source

Carbapenem-hydrolyzing beta-lactamases [PDF]

Antimicrobial Agents and Chemotherapy, 1997
B A, Rasmussen, K, Bush
openaire   +2 more sources

Toddlers and terriers: a One Health partnership to combat antimicrobial resistance

Journal of Small Animal Practice, EarlyView.
M. Prodanuk, F. Emdin
wiley   +1 more source