The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimer’s Disease Models. [PDF]
Cells, 2020 Bécot A +8 more
europepmc +1 more source
Protocol for measuring beta-secretase activity in cell and tissue lysate using a fluorogenic peptide substrate in a 96-well format. [PDF]
STAR ProtocMohammad A +3 more
europepmc +1 more source
Efficacy of Beta-Secretase-1 Enzyme Inhibitors in Alzheimer's Disease
Journal of Advanced Pharmacy Research, 2023 Roohallah Yousefi +2 more
openaire +1 more source
Evaluation of Selected Plant Phenolics via Beta-Secretase-1 Inhibition, Molecular Docking, and Gene Expression Related to Alzheimer's Disease. [PDF]
Pharmaceuticals (Basel)Uçar Akyürek T +5 more
europepmc +1 more source
Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression [PDF]
, 2019 Bateman, Randall J.
core +1 more source
Dose-specific effect of simvastatin on hypoxia-induced HIF-1α and BACE expression in Alzheimer’s disease cybrid cells [PDF]
, 2015 core +1 more source
Serum Beta-Secretase 1 Activity Is a Potential Marker for the Differential Diagnosis between Alzheimer's Disease and Frontotemporal Dementia: A Pilot Study. [PDF]
Int J Mol SciSaraceno C +16 more
europepmc +1 more source
pH-dependent conformational dynamics of beta-secretase 1: A molecular dynamics study. [PDF]
J Mol Recognit, 2019 Mermelstein DJ, McCammon JA, Walker RC.
europepmc +1 more source
Brain-derived neurotrophic factor but not beta-secretase 1, vascular endothelial growth factor, glial fibrillary acidic protein and interleukin-1β correlate with cognitive impairment in adult persons with epilepsy: a cross-sectional single-center study from India. [PDF]
Front NeurolBhavsar K +6 more
europepmc +1 more source
Impact of protein conformations on binding free energy calculations in the beta-secretase 1 system. [PDF]
J Comput ChemBaumann HM, Mobley DL.
europepmc +1 more source