Results 111 to 120 of about 1,179,204 (384)
Molecular Genetics of Intracranial Meningiomas with Emphasis on Canonical Wnt Signalling. [PDF]
, 2016 Research over the last decade recognized the importance of novel molecular pathways in pathogenesis of intracranial meningiomas. In this review, we focus on human brain tumours meningiomas and the involvement of Wnt signalling pathway genes and proteins ...
Kafka, Anja +2 more
core +2 more sources
Concrete Solution to the Nonsingular Quartic Binary Moment Problem [PDF]
, 2014 Given real numbers $\beta \equiv \beta ^{\left( 4\right) }\colon \beta_{00}$, $\beta _{10}$, $\beta _{01}$, $\beta _{20}$, $\beta _{11}$, $ \beta _{02}$, $\beta _{30}$, $\beta _{21}$, $\beta _{12}$, $\beta _{03}$, $\beta _{40}$, $\beta _{31}$, $\beta _{22}$, $\beta _{13}$, $\beta _{04}$, with $\beta _{00} >0$, the quartic real moment problem for $\beta
arxiv +1 more source
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
PLoS Biology, 2006 Beta-catenin plays an essential role in several biological events including cell fate determination, cell proliferation, and transformation. Here we report that beta-catenin is encoded by a labile transcript whose half-life is prolonged by Wnt and ...
Roberto Gherzi +9 more
doaj +1 more source
The potential involvement of E-cadherin and beta-catenins in meningioma. [PDF]
PLoS ONE, 2010 OBJECTIVE: To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS: Immunohistochemistry staining was performed on samples from patients with meningioma.
Keiyu Zhou +5 more
doaj +1 more source
Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARalpha and PLZF/RARalpha [PDF]
, 2011 Chromosomal translocations can lead to the formation of chimeric genes encoding fusion proteins such as PML/RARalpha, PLZF/RARalpha, and AML-1/ETO, which are able to induce and maintain acute myeloid leukemia (AML). One key mechanism in leukemogenesis is
Hagemeyer, Heike +6 more
core
A p53 Oscillator Model of DNA Break Repair Control [PDF]
arXiv, 2005 The transcription factor p53 is an important regulator of cell fate. Mutations in p53 gene are associated with many cancers. In response to signals such as DNA damage, p53 controls the transcription of a series of genes that cause cell cycle arrest during which DNA damage is repaired, or triggers programmed cell death that eliminates possibly cancerous
arxiv
Neutrinoless double beta decay experiment [PDF]
arXiv, 2020 The search for neutrinoless double beta decay ($0\nu\beta\beta$) is one of the key experiments for determining unresolved properties of neutrinos. Experimental observation of $0\nu\beta\beta$ would provide a clear demonstration of the Majorana nature of neutrinos and a lepton number violating process in particle physics.
arxiv
Diagnostic Pathology, 2013 BackgroundDespite their pivotal roles in colorectal carcinogenesis, the interrelationship and prognostic significance of beta-catenin alterations and microsatellite instability (MSI) in colorectal cancer (CRC) needs to be further clarified. In this paper,
S. Wangefjord +5 more
semanticscholar +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
wiley +1 more source