Results 151 to 160 of about 1,179,204 (384)

The orbit of a $β$-transformation cannot lie in a small interval [PDF]

Journal of the Korean Mathematical Society 49 (2012), no. 4, 867-879
For $\beta>1$, let $T_\beta:[0,1]\rightarrow [0,1)$ be the $\beta$-transformation. We consider an invariant $T_\beta$-orbit closure contained in a closed interval with diameter $1/\beta$, then define a function $\Xi(\alpha,\beta)$ by the supremum of such $T_\beta$-orbit with frequency $\alpha$ in base $\beta$, i.e., the maximum value in the $T_\beta ...
arxiv   +1 more source

The CRL7FBXW8 Complex Controls the Mammary Stem Cell Compartment through Regulation of NUMB Levels

Advanced Science, EarlyView.
In breast cancer (BC), NUMB loss of function (LOF) is common and mainly driven by protein hyper‐degradation. The CRL7FBXW8 complex is the E3 ligase responsible for NUMB degradation. Inhibition of CRL7FBXW8 in NUMB‐LOF BC cells restores NUMB levels, and decreases the number of cancer stem cells and tumorigenic ability in vivo. Targeting CRL7FBXW8 offers
Simone Sabbioni, Maria Grazia Filippone, Letizia Amadori, Stefano Confalonieri, Roberta Bonfanti, Stefano Capoano, Ivan Nicola Colaluca, Stefano Freddi, Giovanni Bertalot, Giovanni Fagà, Elisa Zagarrí, Mario Varasi, Rosalind Helen Gunby, Ciro Mercurio, Salvatore Pece, Pier Paolo Di Fiore, Daniela Tosoni   +16 more
wiley   +1 more source

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Two bifurcation sets arising from the beta transformation with a hole at $0$ [PDF]

arXiv, 2019
Given $\beta\in(1,2],$ the $\beta$-transformation $T_\beta: x\mapsto \beta x\pmod 1$ on the circle $[0, 1)$ with a hole $[0, t)$ was investigated by Kalle et al.~(2019). They described the set-valued bifurcation set \[ \mathcal E_\beta:=\{t\in[0, 1): K_\beta(t')\ne K_\beta(t)~\forall t'>t\}, \] where $K_\beta(t):=\{x\in[0, 1): T_\beta^n(x)\ge t~
arxiv  

Beta‐Catenin Expression in Pediatric Malignancies

The FASEB Journal, 2008
Wnt/β‐catenin signaling is important in normal liver growth and development where it dictates processes of proliferation, zonation and metabolism. Here we examined pediatric hepatoblastoma (HB), hepatocellular cancer (HCC) and tyrosinemias for expression of β‐catenin, its target Glutamine synthetase (GS) and upstream effector glypican‐3 (GPC3) by ...
Sarangarajan Ranganathan, Satdarshan P.S. Monga, Benjamin Cieply   +2 more
openaire   +2 more sources

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Induction of a secondary body axis in Xenopus by antibodies to beta-catenin. [PDF]

, 1993
Pierre D. McCrea, William M. Brieher, Barry M. Gumbiner   +2 more
openalex   +1 more source

Double beta decay experiments: past and present achievements [PDF]

arXiv, 2006
A brief history of double beta decay experiments is presented. The best currently running experiments (NEMO-3 and CUORICINO) and their latest results are described. The best measurements and limits for the $2\nu\beta\beta$, $0\nu\beta\beta$ and $0\nu\chi^{0}\beta\beta$ are summarized.
arxiv  

Accurate Delivery of Mesenchymal Stem Cell Spheroids With Platelet‐Rich Fibrin Shield: Enhancing Survival and Repair Functions of Sp‐MSCs in Diabetic Wound Healing

Advanced Science, EarlyView.
Autologous plasma‐derived platelet‐rich fibrin (PRF) is prepared as a protective shield for mesenchymal stem cell spheroids (Sp‐MSCs). PRF forms a fibrin shield to protect Sp‐MSCs from the oxidative stress environment. The nutrients in PRF, particularly the α‐granules, can enhance the repair function of Sp‐MSCs.
Jinglve Zhang, Wenqing Xu, Yutian Xiao, Dingheng Su, Yusheng He, Huohong Yang, Yixin Xie, Xiaofang Wang, Ren‐He Xu, Shaorong Lei, Dingyu Wu   +10 more
wiley   +1 more source

Regulated binding of PTP1B-like phosphatase to N-cadherin: control of cadherin-mediated adhesion by dephosphorylation of beta-catenin. [PDF]

, 1996
J. Bálsamo, TinChung Leung, H Ernst, Mary K.B. Zanin, S Hoffman, Jack Lilien   +5 more
openalex   +1 more source