Results 161 to 170 of about 1,179,204 (384)

Beta-conjugates of real algebraic numbers as Puiseux expansions [PDF]

open access: yesIntegers (2011), 2011
The beta-conjugates of a base of numeration $\beta > 1$, $\beta$ being a Parry number, were introduced by Boyd, in the context of the R\'enyi-Parry dynamics of numeration system and the beta-transformation. These beta-conjugates are canonically associated with $\beta$. Let $\beta > 1$ be a real algebraic number.
arxiv  

PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma

open access: yesAdvanced Science, EarlyView.
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang   +11 more
wiley   +1 more source

BAG2 Inhibits Cervical Cancer Progression by Modulating Type I Interferon Signaling through Stabilizing STING

open access: yesAdvanced Science, EarlyView.
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao   +6 more
wiley   +1 more source

TMF inhibits miR-29a/Wnt/β-catenin signaling through upregulating Foxo3a activity in osteoarthritis chondrocytes

open access: yesDrug Design, Development and Therapy, 2019
Xianhua Huang*, Zhixi Chen*, Weimei Shi, Rui Zhang, Linfu Li, Hai Liu, Longhuo WuCollege of Pharmacy, Gannan Medical University, Ganzhou, People’s Republic of China*These authors contributed equally to this work Background: miR-29a, a downstream ...
Huang X   +6 more
doaj  

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift. [PDF]

open access: bronze, 1995
Hiroshi Takeda   +6 more
openalex   +1 more source

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

open access: yesAdvanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang   +13 more
wiley   +1 more source

FOXM1 promotes the growth and metastasis of colorectal cancer via activation of β-catenin signaling pathway

open access: yesCancer Management and Research, 2019
Kankan Yang,1,* Bing Jiang,1,* Yecai Lu,1,* Qingbing Shu,1 Pan Zhai,1 Qiaoming Zhi,2 Qixin Li1 1Department of Gastrointestinal Surgery, Chaohu Hospital of Anhui Medical University, Hefei 238000, Anhui, China; 2Department of General Surgery, The First ...
Yang K   +6 more
doaj  

The $β$-transformation with a hole at 0 [PDF]

open access: yesarXiv, 2018
For $\beta\in(1,2]$ the $\beta$-transformation $T_\beta: [0,1) \to [0,1)$ is defined by $T_\beta ( x) = \beta x \pmod 1$. For $t\in[0, 1)$ let $K_\beta(t)$ be the survivor set of $T_\beta$ with hole $(0,t)$ given by \[K_\beta(t):=\{x\in[0, 1): T_\beta^n(x)\not \in (0, t) \textrm{ for all }n\ge 0\}.\] In this paper we characterise the bifurcation set ...
arxiv  

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

open access: yesAdvanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang   +5 more
wiley   +1 more source

Expressions of Frat and beta-catenin in lung cancer and their clinicopathological correlations

open access: yesChinese Journal of Lung Cancer, 2008
Background and objective Frat proteins are positive regulator of Wnt-signal transduction.By binding to GSK3,Frat prevents the phosphorylation and concomitant degradation of beta-catenin and allows the activation of downstream targetgenes by beta-catenin ...
Ning GUO   +3 more
doaj  

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