Results 211 to 220 of about 163,717 (335)

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

Improvement of Dentin Growth Parameters (Beta-catenin, bFGF, CD105, and BMP4) with Propolis as Adjuvant in Dental Caries Treatment. [PDF]

Eur J Dent
Rahayu RP, Pribadi N, Widjiastuti I, Nugrahani NA.   +3 more
europepmc   +1 more source

SIRT2 inhibition by AGK2 enhances mycobacteria-specific stem cell memory responses by modulating beta-catenin and glycolysis. [PDF]

iScience, 2023
Bhaskar A, Pahuja I, Negi K, Verma A, Ghoshal A, Mathew B, Tripathi G, Maras JS, Chaturvedi S, Dwivedi VP.   +9 more
europepmc   +1 more source

Borealin Promotes Tumor Growth and Metastasis by Activating the Wnt/β-Catenin Signaling Pathway in Hepatocellular Carcinoma

, 2022
Baiyang Chen, Yang Gu, Hui Shen, Qiangsheng Liu, Hongbo Wang, Yabo Li, Xifan Liu, Yu Liu, Qinghao Du, Huapeng Sun, Xiaofeng Liao   +10 more
openalex   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

The crucial role of beta-catenin in the osteoprotective effect of semaglutide in an ovariectomized rat model of osteoporosis. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Abo-Elenin MHH, Kamel R, Nofal S, Ahmed AAE.   +3 more
europepmc   +1 more source

PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression. [PDF]

Exp Biol Med (Maywood), 2022
Zhang N, Liu S, Xu J, Ning T, Xie S, Min L, Zhu S, Zhang S, Zhu S.   +8 more
europepmc   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

Epigenetic modulation of thyroid cancer metastasis and glycolysis through circSSU72-mediated ubiquitination of gamma-catenin and beta-catenin signaling. [PDF]

Genes Dis
Zhang Z, Su D, Qiu X, Yao L, Xia F, Li X.   +5 more
europepmc   +1 more source

Biclonal Desmoid-Type Fibromatosis With Two Beta-Catenin Mutations: Evidence for the Recruitment of Normal Myofibroblasts. [PDF]

Cureus, 2022
Skubitz KM, Murugan P, Corless CL.
europepmc   +1 more source