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SARS-CoV-2 variant biology: immune escape, transmission and fitness
Nature Reviews Microbiology, 2023Alessandro Maria Carabelli +2 more
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Wnt/β-catenin signaling in cancers and targeted therapies
Signal Transduction and Targeted Therapy, 2021Feifei Li, Chenglin Wang, Ling Ye
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2007
Beta-catenin is a 92-kDa protein first identified as a molecule associated with the cytoplasmic tail of E-cadherin, as it links E-cadherin to the cytoskeleton. It is a key element in the WNT pathway. In the cytoplasm, beta-catenin forms a complex together with adenomatous polyposis coli (APC) tumor suppressor protein, axin and GSK3beta.
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Beta-catenin is a 92-kDa protein first identified as a molecule associated with the cytoplasmic tail of E-cadherin, as it links E-cadherin to the cytoskeleton. It is a key element in the WNT pathway. In the cytoplasm, beta-catenin forms a complex together with adenomatous polyposis coli (APC) tumor suppressor protein, axin and GSK3beta.
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Signal transduction of beta-catenin.
Current opinion in cell biology, 1996Beta-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus.
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Nihon rinsho. Japanese journal of clinical medicine, 2002
K, Ogawa, Y, Yaginuma
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K, Ogawa, Y, Yaginuma
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β-Catenin hits chromatin: regulation of Wnt target gene activation
Nature Reviews Molecular Cell Biology, 2009Christian Mosimann +2 more
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