Results 211 to 220 of about 2,087,290 (305)

Complete loss of SLC30A8 in humans improves glucose metabolism and beta cell function. [PDF]

Diabetologia
Lamarche LB, Koch C, Khalid S, Khan MZ, Zessis R, Clement ME, Denning DP, Goldfine AB, Splawski I, Abbasi A, Harrow JL, Underwood C, Tsunoyama K, Asaumi M, Kou I, Rodriguez-Flores JL, Shuldiner AR, Rasheed A, Jahanzaib M, Mian MR, Liaqat MB, Abdulsalam U, Sultana R, Jalal A, Saeed MH, Abbas S, Memon FR, Ishaq M, Gurtan AM, Dominy JE, Saleheen D.   +30 more
europepmc   +1 more source

Beta cell nesidioblastosis.

Indian pediatrics, 1986
S R, Daga, V C, Talwalkar, Y, Mukadam, S B, Nagle   +3 more
openaire   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Empagliflozin for the preservation of beta-cell function in women with recent gestational diabetes: A randomized placebo-controlled trial. [PDF]

Diabetes Obes Metab
Murugavel S, Retnakaran R, Feig DS, Zinman B, Kramer CK.   +4 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Beta cell secreted GABA sets appropriate insulin secretion by modulating islet calcium oscillations. [PDF]

Mol Metab
Ferreira SM, Hagan DW, Stis AE, Widener AE, Cuaycal AE, Rancourt C, Readey AG, Smurlick DS, Fu DA, Campbell-Thompson M, Rupnik MS, Phelps EA.   +11 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Ketoacidosis at childhood type 1 diabetes onset negatively affects residual beta-cell functions during the first year after diagnosis. [PDF]

Sci Rep
Niechciał E, Wais P, Kędzia A.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source