Ignoring Information Quality [PDF]
, 2021 Entry into the patent system is guarded by an examination process to screen out applications that impose undue costs on the public without commensurate benefit.
Freilich, Janet
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Serum betatrophin level increased in subjects with metabolic syndrome: a case-control study
Nutrición HospitalariaBackground: Betatrophin is a novel adipokine that provokes pancreatic β-cell proliferation and is involved in lipid metabolism. Aims: This study aims to evaluate the role of serum betatrophin in metabolic syndrome (MetS).
Zhu Jin-Zhou +9 more
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Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway [PDF]
, 2014 Dysfunction or death of pancreatic β cells underlies both types of diabetes. This functional decline begins with β cell stress and de-differentiation. Current drugs for type 2 diabetes (T2D) lower blood glucose levels but they do not directly alleviate β
Arvanites, Anthony C +9 more
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Circular Pentraxin-3 and Betatrophin as Novel Predictors and Promising Biomarkers in Polycystic Ovary Syndrome with or without Type 2 Diabetes Mellitus [PDF]
Background: Two recently discovered circulating proteins, pentraxin 3 (PTX3) and betatrophin, have a strong correlation with a number of illnesses, obesity, and the metabolic syndrome.
Al-Fartosy, Adnan Jassim Mohammed +1 more
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Gestational diabetes mellitus — literature review on selected cytokines and hormones of confirmed or possible role in its pathogenesis [PDF]
, 2018 The incidence of gestational diabetes mellitus (GDM) increases globally, including Poland. Considering serious consequences of gestational diabetes for both mother and fetus, screening for this disorder is an obligatory element of managing pregnant woman.
Dudzińska, Marta +4 more
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Journal of Diabetes Research, 2016 Betatrophin and irisin are two recently identified hormones which may participate in regulating pancreatic β-cell function. However, the associations of these two hormones with β-cell function remain unclear.
Lingshu Wang +14 more
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Correlation of Circulating ANGPTL5 Levels With Obesity, High Sensitivity C-Reactive Protein and Oxidized Low Density Lipoprotein in Adolescents [PDF]
, 2020 Angiopoietin-like proteins (ANGPTL) is a family of eight members known to play an important role in metabolic diseases. Of these, ANGPTL5 is suggested to regulate triglyceride metabolism and is increased in obesity and diabetes.
Abu-Farha, Mohamed +8 more
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The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3 [PDF]
, 2016 We previously identified a locus linked to total cholesterol (TC) concentration in Pima Indians on chromosome 19p. To characterize this locus, we genotyped \u3e2000 SNPs in 1838 Pimas and assessed association with log(TC).
Almasy, Laura +10 more
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[Betatrophin - the turn in diabetes treatment].
Pediatric endocrinology, diabetes, and metabolism, 2017 The topic of the present work is the appearance of the newest research in diabetes treatment. Till now, the patients were forced to inject insulin or take oral medicines to maintain proper glucose level. Introduction of the incretin group of medicines to the market turned out to be a breakthrough in diabetes treatment.
Zygmunt, Zdrojewicz +4 more
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RUTIN RESTORE BIOCHEMICAL CHANGES, OXIDATIVE STRESS AND BETATROPHIN LEVEL IN STZ-INDUCED DIABETIC RATS [PDF]
, 2019 Objective: Diabetes mellitus (DM) is associated with long-term damage, dysfunction, of various organs. Study aims to assessrole of rutin on experimentally induced diabetes. Methods: 50 adult male albino rats divided into 5 groups. Group I (control group,
ABAS, AL-SHIMAA M. +2 more
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