Results 151 to 160 of about 2,690,513 (210)

Gut microbe-derived betulinic acid alleviates sepsis-induced acute liver injury by inhibiting macrophage NLRP3 inflammasome in mice. [PDF]

mBio
Tang X, Zeng T, Deng W, Zhao W, Liu Y, Huang Q, Deng Y, Xie W, Huang W.   +8 more
europepmc   +1 more source

The antioxidant betulinic acid enhances porcine oocyte maturation through Nrf2/Keap1 signaling pathway modulation. [PDF]

PLoS One
Kim MJ, Kang HG, Jeon SB, Yun JH, Jeong PS, Sim BW, Kim SU, Cho SK, Song BS.   +8 more
europepmc   +1 more source

Enhanced ZBTB10 expression induced by betulinic acid inhibits gastric cancer progression by inactivating the ARRDC3/ITGB4/PI3K/AKT pathway. [PDF]

Cell Oncol (Dordr)
Huang Z, Li Y, Zhao Z, Ye L, Zhang T, Yu Z, Zhai E, Qian Y, Xu X, Zhao R, Cai S, Chen J.   +11 more
europepmc   +1 more source

Betulinic Acid Increases the Lifespan of Drosophila melanogaster via Sir2 and FoxO Activation. [PDF]

Nutrients
Lee HY, Min KJ.
europepmc   +1 more source

Correction: Combination of betulinic acid and EGFR‑TKIs exerts synergistic anti‑tumor effects against wild‑type EGFR NSCLC by inducing autophagy‑related cell death via EGFR signaling. [PDF]

Respir Res
Wang H, Du X, Liu W, Zhang C, Li Y, Hou J, Yu Y, Li G, Wang Q.   +8 more
europepmc   +1 more source

Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies. [PDF]

BMC Chem
Zuma LK, Pooe OJ, Mabaso NH, Alake J, Obakachi VA, Yakobi S, Gasa N, Karpoormath R, Simelane M.   +8 more
europepmc   +1 more source

Design and synthesis of betulinic acid-dithiocarbamate conjugates as potential antifungal agents against Candida albicans. [PDF]

RSC Adv
Amin H, Kantroo HA, Mubarak MM, Bhat SA, Ahmad Z, Bhat KA.   +5 more
europepmc   +1 more source

Betulinic Acid for Cancer Treatment and Prevention [PDF]

International Journal of Molecular Sciences, 2008
Betulinic acid is a natural product with a range of biological effects, for example potent antitumor activity. This anticancer property is linked to its ability to induce apoptotic cell death in cancer cells by triggering the mitochondrial pathway of apoptosis.
Simone Fulda
exaly   +6 more sources

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Synthesis and Cytotoxicity of Bidesmosidic Betulin and Betulinic Acid Saponins

Journal of Natural Products, 2008
The naturally occurring cytotoxic saponin 28-O-beta-d-glucopyranosylbetulinic acid 3beta-O-alpha-l-arabinopyranoside (3) was easily synthesized along with seven bidesmosidic saponins starting from the lupane-type triterpenoids betulin (1) and betulinic acid (2). As highlighted by the preliminary cytotoxicity evaluation against A549, DLD-1, MCF7, and PC-
Gauthier, Charles, Legault, Jean, Lavoie, Serge, Rondeau, Simon, Tremblay, Samuel, Pichette, André   +5 more
openaire   +3 more sources

Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity

Bioorganic & Medicinal Chemistry, 2005
Synthesis of 3beta-O-phthalic esters from betulinic acid and its esters and synthesis of phthalic esters from betulin and its monoacetates using classical acylation procedure with phthalic anhydride. The evaluation of cytotoxicity of the prepared compounds was using numbers of tumor cell lines in MTT test. It was discovered that hemiphthalic esters had
Miroslav, Kvasnica, Jan, Sarek, Eva, Klinotova, Petr, Dzubak, Marian, Hajduch   +4 more
openaire   +2 more sources