Results 81 to 90 of about 2,690,513 (210)
ChemistryOpen, Volume 15, Issue 9, September 2026.An endemic Aurès chemotype of Salvia balansae emerges as a rich source of luteolin, rosmarinic acid, and other polyphenols with potent antioxidant and NLRP3‐linked anti‐inflammatory activities. Protection against experimental inflammation, favorable enzyme‐modulating properties, and a wide safety margin highlight its promise as a pharmaceutical and ...
Khadra Afaf Bendrihem +16 more
wiley +1 more source
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Stimulating proteasomal degradation in human proteinopathies
The FEBS Journal, Volume 293, Issue 18, Page 5514-5540, September 2026.The proteasome mediates the degradation of a wide range of proteins. Boosting proteasomal degradation may be beneficial in several disease contexts and can be achieved either by modulating proteasome activity or by improving substrate delivery. Proteasome activity can be enhanced by increasing proteasome abundance, inducing constitutive gate opening ...
Maria E. Gierisch +2 more
wiley +1 more source
Exploration of the Antiplatelet Activity Profile of Betulinic Acid on Human Platelets
, 2016 Betulinic acid, a natural pentacyclic triterpene acid, presents a diverse mode of biological actions including antiretroviral, antibacterial, antimalarial, and anti-inflammatory activities.
Maria Tsoumani (2063647) +6 more
core +1 more source
Constituintes químicos de Hyptidendron canum (Pohl ex Benth.) R. Harley (Lamiaceae)
Química Nova, 2011 Chemical investigation of Hyptidendron canum stems resulted in the isolation of betulinic, ursolic and euscaphic acids. From the leaves were isolated 3β-O-β-galactopiranosilsitosterol, ursolic aldehyde, and mixtures of maslinic acid and 2α-hydroxyursolic
Geralda de Fátima Lemes +2 more
doaj +1 more source
Natural Product Communications, 2008 Phytochemical investigation of the stem bark of Lonchocarpus laxiflorus yielded three new cassane diterpenoids, lonchocassane A [cassa-13 (14), 15-dien-18, 20-dioic acid], lonchocassane B [cassa-13 (14), 15-dien-20-oxo-18-oic acid] and lonchocassane C ...
John O. Igoli +4 more
doaj +1 more source
Correction: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy [PDF]
, 2019 Correction to: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and ...
Goto, Masuo +15 more
core +1 more source
Discovery and mechanism of betulinic acid and natural product estrogens and antiestrogens.
, 1998 Discovery and mechanism of betulinic acid and natural product estrogens and ...
Emily. Pisha (7952489)
core +2 more sources
Cytotoxic and Antileishmanial Components from the Bark Extract of from Monteverde, Costa Rica
Natural Product Communications, 2017 The bark of Ruyschia phylladenia was collected from Monteverde, Costa Rica, and extracted with acetone. Bioactivity-directed chromatographic separation of the crude acetone bark extract of R.
Kelly Marie Steinberg +6 more
doaj +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2019 Trichomonas vaginalis and Leishmania spp. are protozoal species responsible for millions of cases of parasitic diseases worldwide. Considering the potential of natural products and the need for more effective and less toxic alternatives to treat ...
Simone Tasca Cargnin +7 more
doaj +1 more source