Results 61 to 70 of about 2,690,513 (210)

Clinical outcomes of intratumoural para‐toluenesulfonamide treatment in equine melanoma

Equine Veterinary Education, Volume 38, Issue 11, Page e821-e829, November 2026.
Summary Equine melanoma is one of the most common cutaneous neoplasms in horses and is particularly prevalent in grey horses. Although these tumours often demonstrate indolent biological behaviour, some progressively develop locally invasive or malignant characteristics over time, making treatment decisions challenging in clinical practice.
H.‐C. Lo, H. Yan‐Der, P.‐L. Chang, M.‐Y. Lin, S. Kee   +4 more
wiley   +1 more source

Ethnomedicinal and Phytopharmaceutical Properties of Syzygium samarangense (Blume) Merr. & L.M. Perry: A Gateway to Future Drug Development

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
ABSTRACT Recently, natural products and plant‐based regimens are widely recognized as potential complementary and alternative therapeutic solutions. Traditionally, ethnomedicinal knowledge, validated through scientific evidence, has been a basis for modern drug discovery, emphasizing the importance of updated phytopharmacological knowledge of medicinal
Sujit Kumar Patro, Rudra Narayan Sahoo, Ashirbad Nanda, Shasank S. Swain   +3 more
wiley   +1 more source

Formulation And Evaluation of Betulinic Acid Loaded Transdermal Patches [PDF]

Many disorders, including cardiovascular diseases, Parkinson\u27s disease, Alzheimer\u27s disease, fungal diseases, depression, anxiety, and Attention Deficit Hyperactivity Disorder (ADHD), skin cancer, female sexual dysfunction, post-menopausal bone ...
Bose , Prashanta, Singh, Harmanjit, Singh , Amar Pal, Singh , Ajeet Pal   +3 more
core   +1 more source

Preparation of Poly (dl-Lactide-co-Glycolide) Nanoparticles Encapsulated with Periglaucine A and Betulinic Acid for In Vitro Anti-Acanthamoeba and Cytotoxicity Activities

Pathogens, 2018
Poly (dl-lactide-co-glycolide) (PLGA) microspheres were synthesized as delivery system for the natural anti-parasitic compounds, Periglaucine A (PGA) and Betulinic acid (BA).
Tooba Mahboob, Muhammad Nawaz, Tan Tian-Chye, Chandramathi Samudi, Christophe Wiart, Veeranoot Nissapatorn   +5 more
doaj   +1 more source

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source

Anti-AIDS agents 73: Structure–activity relationship study and asymmetric synthesis of 3-O-monomethylsuccinyl-betulinic acid derivatives [PDF]

, 2007
3-O-3′(or 2′)-methylsuccinyl-betulinic acid (MSB) derivatives were separated by using recycle HPLC. The structures of four isomers were assigned by NMR and asymmetric synthesis. 3-O-3′S-Methylsuccinyl-betulinic acid (3′S-MSB, 4) exhibited potent anti-HIV
Allaway, Graham, Qian, Keduo, Kilgore, Nicole, Lee, Kuo-Hsiung, Yu, Donglei, Morris-Natschke, Susan, Nitz, Theodore, Nakagawa-Goto, Kyoko   +7 more
core   +1 more source

New Pharmacological Opportunities for Betulinic Acid [PDF]

Planta Medica, 2017
AbstractBetulinic acid is a naturally occurring pentacyclic lupane-type triterpenoid usually isolated from birch trees, but present in many other botanical sources. It is found in different plant organs, both as a free aglycon and as glycosyl derivatives.
José Luis, Ríos, Salvador, Máñez
openaire   +2 more sources

Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control

Advanced Materials Interfaces, Volume 13, Issue 18, 22 September 2026.
In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah, Szymon Smołka, Kamran Ayaz, Sara Shakibania, Sajida Maryam, Taral Patel, Roman Turczyn, Ewa Zabłocka‐Godlewska, Katarzyna Krukiewicz   +8 more
wiley   +1 more source

Exploration of the Antiplatelet Activity Profile of Betulinic Acid on Human Platelets

, 2012
Betulinic acid, a natural pentacyclic triterpene acid, presents a diverse mode of biological actions including antiretroviral, antibacterial, antimalarial, and anti-inflammatory activities.
Hwa, John, Tzakos, Andreas G., Tselepis, Alexandros D., Kontogianni, Vassiliki G., Rodrigues, Francisco A., Tsoumani, Maria, Kyriakou, Eleni   +6 more
core   +2 more sources

Novel Diterpenoids From Salvia rosmarinus Reveal a Compound With Antiproliferative and Antioxidant Activities

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
Four novel diterpenoids were isolated from Salvia rosmarinus (rosemary), together with nine known compounds. ECD calculations were employed to establish the absolute configuration of diterpenoids 1 and 2. The 18‐hydroxycarnosol (1) was evaluated as antiproliferative (SRB assay) and antioxidant (DPPH and TBARS), showing promising results.
Diana Pérez‐Juanchi, Celia Bustos‐Brito, Ma. Teresa Ramírez‐Apan, Antonio Nieto‐Camacho, Leovigildo Quijano, Baldomero Esquivel   +5 more
wiley   +1 more source