Results 61 to 70 of about 6,141 (135)

Multi‐Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Amal Elrherabi, Oussama Khibech, Mohamed Bouhrim, Abdelouahid Laftouhi, Abdelaaty A. Shahat, Abdullah R. Alanzi, Rashed N. Herqash, Joe Miantezila Basilua, Mohamed Bnouham   +8 more
wiley   +1 more source

Cassane diterpenoids from

Natural Product Communications, 2008
Phytochemical investigation of the stem bark of Lonchocarpus laxiflorus yielded three new cassane diterpenoids, lonchocassane A [cassa-13 (14), 15-dien-18, 20-dioic acid], lonchocassane B [cassa-13 (14), 15-dien-20-oxo-18-oic acid] and lonchocassane C ...
John O. Igoli, Samuel O. Onyiriuka, Matthias C. Letzel, Martin N. Nwaji, Alexander I. Gray   +4 more
doaj   +1 more source

Cytotoxic and Antileishmanial Components from the Bark Extract of from Monteverde, Costa Rica

Natural Product Communications, 2017
The bark of Ruyschia phylladenia was collected from Monteverde, Costa Rica, and extracted with acetone. Bioactivity-directed chromatographic separation of the crude acetone bark extract of R.
Kelly Marie Steinberg, Samon Shrestha, Noura S. Dosoky, Lianet Monzote, Abel Piñón, William A. Haber, William N. Setzer   +6 more
doaj   +1 more source

Evaluation of triterpenes derivatives in the viability of Leishmania amazonensis and Trichomonas vaginalis

Brazilian Journal of Pharmaceutical Sciences, 2019
Trichomonas vaginalis and Leishmania spp. are protozoal species responsible for millions of cases of parasitic diseases worldwide. Considering the potential of natural products and the need for more effective and less toxic alternatives to treat ...
Simone Tasca Cargnin, Andressa Finkler Staudt, Camila Menezes, Ana Paula de Azevedo, Saara Neri Fialho, Tiana Tasca, Carolina Bioni Garcia Teles, Simone Baggio Gnoatto   +7 more
doaj   +1 more source

Assessing Chemical Constituents of Mimosa caesalpiniifolia Stem Bark: Possible Bioactive Components Accountable for the Cytotoxic Effect of M. caesalpiniifolia on Human Tumour Cell Lines

Molecules, 2015
Mimosa caesalpiniifolia is a native plant of the Brazilian northeast, and few studies have investigated its chemical composition and biological significance.
Nayana Bruna Nery Monção, Bruno Quirino Araújo, Jurandy do Nascimento Silva, Daisy Jereissati Barbosa Lima, Paulo Michel Pinheiro Ferreira, Flavia Pereira da Silva Airoldi, Cláudia Pessoa, Antonia Maria das Graças Lopes Citó   +7 more
doaj   +1 more source

Ethylenediamine Derived Carboxamides of Betulinic and Ursolic Acid as Potential Cytotoxic Agents

Molecules, 2018
Two easily accessible, natural occurring triterpenoids, betulinic and ursolic acid, were used as starting materials for the synthesis of novel cytotoxic agents.
Michael Kahnt, Lucie Fischer (née Heller), Ahmed Al-Harrasi, René Csuk   +3 more
doaj   +1 more source

Lupane acetates in small molecule drug hybrids: Probing their inhibitory activity for carbonic anhydrase II

European Journal of Medicinal Chemistry Reports
Earlier studies had shown the potential of modified pentacyclic triterpenes as possible inhibitors of carbonic anhydrase II (CA II). In an extension of our earlier studies, betulin, betulinic acid and, for comparison purposes, glycyrrhetinic acid ...
Toni-Christopher Denner, Niels V. Heise, Julian Zacharias, René Csuk   +3 more
doaj   +1 more source

Standardized Herbal Lozenges Containing Extract: A Novel Approach for Respiratory Health Support

Natural Product Communications
Objectives Schefflera leucantha leaves have traditionally been used to relieve respiratory symptoms. This study aimed to develop and evaluate a stable herbal lozenge containing S. leucantha extract, emphasizing physicochemical properties, standardization
Juthaporn Ponphaiboon, Jongjan Mahadlek, Sarun Tuntarawongsa, Manachai Ingsurarak, Witoon Auparigtatipong, Lawan Siangjong, Paranee Meetam, Wantanwa Krongrawa, Jittiphaiboon Eka Champaka, Katekeaw Sarunyakasitrin, Sontaya Limmatvapirat, Chutima Limmatvapirat   +11 more
doaj   +1 more source

Optimization of betulinic and ursolic acids and phenolics extraction from endemic Rosa pisiformis using Box-Behnken design in relation to cytotoxic activities

Scientific Reports
Despite its important pharmacological bioactivities, betulinic acid is still primarily obtained through extraction from heartwood and bark or synthesized synthetically, with less than 3% efficiency.
Hatice Demiray, Mesut Emir Dibek, Onur Özel   +2 more
doaj   +1 more source

Synthesis and Cytotoxicity of Complex Betulinic Acid Amides. [PDF]

ACS Omega
Wimmerová M, Kyjaková P, Šaman D, Wimmer Z.   +3 more
europepmc   +1 more source