Results 51 to 60 of about 2,513,921 (167)

Preparation of Poly (dl-Lactide-co-Glycolide) Nanoparticles Encapsulated with Periglaucine A and Betulinic Acid for In Vitro Anti-Acanthamoeba and Cytotoxicity Activities

Pathogens, 2018
Poly (dl-lactide-co-glycolide) (PLGA) microspheres were synthesized as delivery system for the natural anti-parasitic compounds, Periglaucine A (PGA) and Betulinic acid (BA).
Tooba Mahboob, Muhammad Nawaz, Tan Tian-Chye, Chandramathi Samudi, Christophe Wiart, Veeranoot Nissapatorn   +5 more
doaj   +1 more source

Anti-Inflammatory Activities of Betulinic Acid: A Review

Frontiers in Pharmacology, 2022
Inflammatory diseases have a high prevalence and has become of great interest due to the increase in life expectancy and the costs to the health care system worldwide.
José Fernando Oliveira-Costa, Cássio Santana Meira, Cássio Santana Meira, Maria Vitória Gomes das Neves, Bruna Padilha Zurita Claro Dos Reis, Milena Botelho Pereira Soares, Milena Botelho Pereira Soares   +6 more
doaj   +1 more source

Comparative Phytochemical and Biological Evaluation of Four Thymus Species From Türkiye for Dermocosmetic Applications

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Four Thymus species from Anatolia are profiled through molecular networking and multi‐target bioassays across skin‐relevant cellular models. Triterpene‐rich extracts inhibit key anti‐aging enzymes and promote wound closure in fibroblast, keratinocyte, and endothelial cells.
Ebru Özdemir Nath, Pierre‐Eric Campos, Audrey Le Cabec, Gül İpek Gündoğan, Diren Ergin, Ahsen Çetin, Sefa Sönmez, Emilie Destandau   +7 more
wiley   +1 more source

Heparin suppresses FoxO1/pFoxO1 signaling axis in vascular smooth muscle cells

Biochemistry and Biophysics Reports
Background: The atherosclerosis process relates to the dysfunction of different cells in the plaque microenvironment. The vascular smooth muscle cells (VSMCs) play an important role in atherosclerosis.
Nafiseh Shokri, Mohammad Elahimanesh, Masoomeh Bakhshandeh, Mohammad Najafi   +3 more
doaj   +1 more source

Qualitative Analysis of Chemical Composition Changes Before and After Lactobacillus Fermented Ziziphi Spinosae Semen by LC‐MS and Prediction of Fermentation Mechanism

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
ABSTRACT This study aimed to screen dominant Lactobacillus strains for fermenting Ziziphi Spinosae Semen (ZSS), analyze chemical composition changes before and after fermentation, and speculate on the fermentation mechanism. Liquid fermentation of ZSS was conducted using Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus acidophilus, and ...
Jiafu Wan, Yunda Wang, Xiaoxue Yang, Qingmei Guo   +3 more
wiley   +1 more source

Estudo das propriedades químicas e biológcas de Rosmarinus officinalis L. [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2012.Introducao: Rosmarinus officinalis L.
Dalmarco, Juliana Bastos
core  

Anticancer activity of 3-O-acylated betulinic acid derivative obtained by enzymatic synthesis [PDF]

, 2010
An easy and efficient strategy to prepare betulinic acid esters with various anhydrides was used by the enzymatic synthesis method. It involves lipase-catalyzed acylation of betulinic acid with anhydrides as acylating agents in organic solvent.
Abdul Rahman, Mohd Basyaruddin, Ahmad @ Amat, Faujan, Moghaddam, Mansour Ghaffari, Basri, Mahiran   +3 more
core   +1 more source

Effect of 3β, hydroxy-lup-20(29)-en-28-oic acid on 7,12-Dimethylbenz(a) anthracene impaired cellular homeostasis in extrahepatic organs of Sprague Dawley rats

Journal of Xenobiotics, 2017
3β, hydroxy-lup-20(29)-en-28-oic acid (Betulinic acid), a pentacyclic lupane-type triterpene has diverse pharmacological functions both in vitro and in vivo.
Pardeep Kaur, Rajbir Kaur, Rohit Arora, Saroj Arora   +3 more
doaj   +1 more source

Phytochemical profiling and bioactivity evaluation of Anthocephalus cadamba flower extracts through in vitro, and in silico studies

Food Biomacromolecules, Volume 3, Issue 3, Page 664-677, September 2026.
Abstract Anthocephalus cadamba (Kadamba) is a medicinally important tropical plant with well‐documented antioxidant, anti‐inflammatory, and antimicrobial properties. However, comparative evaluation of solvent extraction efficiency combined with computational validation of bioactive compounds remains limited.
Manisha Panchal, Diksha Sharma, Sunita Khatak, Raushan Kumar Jha, Surbhi Panwar, Ashwani Kumar   +5 more
wiley   +1 more source

Betulinic acid inhibits glioma cell viability by downregulation of NF-κB and enhancement of apoptosis [PDF]

, 2021
Purpose: To determine the inhibitory potential of betulinic acid on pro-survival signaling pathway in glioblastoma.Methods: Changes in viabilities of glioma cells and primary astrocytes were measured using 3-(4, 5dimethylthiazol-2-yl)-2,  5 ...
Peng, Peng, Yaozu, Zhu, Liu, Yang, Zhao, Huang, Tingbao, Zhang, Jincao, Chen   +5 more
core   +1 more source