Results 51 to 60 of about 6,141 (135)

Beneficial effect of standardized extracts of Amorphophallus paeoniifolius tuber and its active constituents on experimental constipation in rats

Heliyon, 2020
The tubers of Amorphophallus paeoniifolius (Elephant foot yam), principally consumed as crop food and vegetables, are used in ethno-medicinal practices in mitigation of constipation and piles.
Yadu Nandan Dey, Manish M. Wanjari, Bhavana Srivastava, Dharmendra Kumar, Deepti Sharma, Jyoti Sharma, Sudesh Gaidhani   +6 more
doaj   +1 more source

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

Development of betulinic acid as an agonist of TGR5 receptor using a new in vitro assay

Drug Design, Development and Therapy, 2016
Shih-Hsiang Lo,1,2 Kai-Chung Cheng,3 Ying-Xiao Li,3,4 Chin-Hong Chang,4,5 Juei-Tang Cheng,4,6 Kung-Shing Lee7,8 1Division of Cardiology, Department of Internal Medicine, Zhongxing Branch of Taipei City Hospital, 2Department of History and Geography ...
Lo SH, Cheng KC, Li YX, Chang CH, Cheng JT, Lee KS   +5 more
doaj  

Cedrela fissilis Vell. Inner Bark: LC–MS/MS‐Based Chemical Profiling and Toxicological Effects

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
ABSTRACT Investigating the mechanistic toxicity of plant extracts is essential for safety assessment. The predictive toxicological effects of Cedrela fissilis were evaluated, and LC–MS/MS‐based chemical profiling was performed. The hydroethanolic extract (HeECf) and ethyl acetate (EA) fraction were assessed in multimodel systems with different levels ...
Thainá Pereira da Silva Cabral, Emanuel Victor dos Santos Nunes, Viviani de Brito Massad Gomes da Silva, Fhelipe Jolner Souza de Almeida, Douglas Lisboa Ramalho, Jadyellen Rondon Silva, Anderson de Oliveira Souza, Maria Cristina Fuzari Bezerra, Ian Castro‐Gamboa, Helder Lopes Teles, Mayara Peron Pereira   +10 more
wiley   +1 more source

Characterization and Quantification of Triterpenes in the Neotropical Medicinal Plant (Marcgraviaceae) by HPLC-APCI-MS

Natural Product Communications, 2008
A rapid, two-solvent, HPLC-APCI-MS method was developed to identify and quantify four pentacyclic triterpenes (betulinic acid, ursolic acid, α-amyrin and β-amyrin) in extracts of the neotropical medicinal plant Souroubea sympetala.
Martha Mullally, Kari Kramp, Ammar Saleem, Marco Otorola Rojas, Pablo Sanchez Vindas, Mario Garcia, Luis Poveda Alvarez, Tony Durst, Vance L. Trudeau, John T. Arnason   +9 more
doaj   +1 more source

Major Components of Epicuticular Wax From Fruit of the Canadian Prairies: Saskatoon Berry (Amelanchier alnifolia), Canadian Dwarf Sour Cherry (Prunus × kerrasis), Haskap (Lonicera caerulea), and Red Twinberry (Lonicera utahensis)

European Journal of Lipid Science and Technology, Volume 128, Issue 5, May 2026.
Composition of chloroform extractable surface wax from fruit was determined by GC and GC/MS. The major components of Saskatoon berry wax were nonacosan‐10‐ol and nonacosane. Canadian sour cherry wax was enriched in the pentacyclic triterpenoids and haskap in nonacosan‐10‐ol and nonacosan‐5,10,‐diol. Red twinberry wax contained triterpenoids.
Daniel Hupka, Haixia Zhang, Mark A. Smith   +2 more
wiley   +1 more source

Camellia oleifera Seed Cake Extract Ameliorates Hyperuricemia and Renal Injury by Modulating Uric Acid Metabolism, Nrf2/Keap1 Pathway, and NLRP3 Inflammasome in Mice

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Protective mechanisms of Camellia oleifera seed cake extract (SCE) against hyperuricemia and renal injury via modulation of uric acid metabolism, Nrf2/Keap1 signaling, and NLRP3 inflammasome activation. ABSTRACT Camellia oleifera seed cake is a major byproduct of the oil industry, often underutilized despite its richness in bioactive compounds.
Liting Mai, Youliang Xie, Yingzhong Zhang, Chen Ni, Ying Xu, Lieqiang Xu, Guoshu Lin, Yinsi Lin, Ziren Su, Jing Wang, Mihong Ren   +10 more
wiley   +1 more source

Synthesis and Cytotoxic Activity of New Betulin and Betulinic Acid Esters with Conjugated Linoleic Acid (CLA)

Natural Product Communications, 2013
The synthesis of new ester derivatives of betulin (3a-c) and betulinic acid (4) with conjugated linoleic acid isomers (CLA; in a mixture of 43.4% 9c, 11t; 49.5% 10 t , 12 c ; 7.1% other isomers) is presented.
Barbara Tubek, Paweł Mituła, Natalia Niezgoda, Katarzyna Kempińska, Joanna Wietrzyk, Czesław Wawrzeńczyk   +5 more
doaj   +1 more source

Constituintes químicos de Hyptidendron canum (Pohl ex Benth.) R. Harley (Lamiaceae)

Química Nova, 2011
Chemical investigation of Hyptidendron canum stems resulted in the isolation of betulinic, ursolic and euscaphic acids. From the leaves were isolated 3β-O-β-galactopiranosilsitosterol, ursolic aldehyde, and mixtures of maslinic acid and 2α-hydroxyursolic
Geralda de Fátima Lemes, Pedro Henrique Ferri, Márcia Nasser Lopes   +2 more
doaj   +1 more source

Enhancement of Pentacyclic Triterpenoids (Betulinic and Oleanolic acids) Production from Callus Cultures of Lantana camara L.

Advances in Horticultural Science, 2020
Lantana camara L. is an ornamental plant with high medicinal value. This study aimed to investigate the possibility of enhancing the production of betulinic and oleanolic acids in Lantana callus by adding different types and levels of chemical elicitors (
Anfal Al-Ashoush, Rida Shibli, Reham Tahtamouni, Tamara Al-Qudah, Bashaer Abu-Irarmaileh   +4 more
doaj   +1 more source