Results 31 to 40 of about 2,513,921 (167)

Betulinic Acid for Glioblastoma Treatment: Reality, Challenges and Perspectives. [PDF]

Int J Mol Sci
Betulinic acid is a naturally occurring compound that can be obtained through methanolic or ethanolic extraction from plant sources, as well as through chemical synthesis or microbial biotransformation.
Fernandes S, Vieira M, Prudêncio C, Ferraz R.   +3 more
europepmc   +2 more sources

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Comparison of Different Strains of for Hairy Root Induction and Betulin and Betulinic Acid Production in

Natural Product Communications, 2017
Three Agrobacterium rhizogenes strains were tested for their ability to transform the plant Morus alba L. and to induce production of the secondary metabolites betulin and betulinic acid. All the tested strains of A. rhizogenes (R1601, LBA9402 and R1000)
Chang Ha Park, Shicheng Zhao, Hyeon Ji Yeo, Ye Eun Park, Thanislas Bastin Baska, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Sang Un Park   +7 more
doaj   +1 more source

Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines

Molecules, 2009
Betulin and betulinic acid are naturally occurring pentacyclic triterpenes showing cytotoxicity towards a number of cancer cell lines. These compounds can be found in the bark of the many plants.
Hermann Lage, Józef Oleksyszyn, Malgorzata Drag-Zalesinska, Manfred Dietel, Pawel Surowiak, Marcin Drag   +5 more
doaj   +1 more source

Anti-snake venom and analgesic activities of extracts and betulinic and oleanolic acids isolated from Parinari curatellifolia

Journal of Medicinal Plants for Economic Development, 2020
Background: Parinari curatellifolia is used in Nigeria by traditional medicine practitioners (TMPs) for the treatment of snakebite and other conditions.
Emmanuel Mshelia Halilu, Natasha October, Chinenye J. Ugwah-Oguejiofor, Amina Yusuf Jega, Mathias Sylvester Nefai   +4 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain

Neurobiology of Pain, 2023
Over the past three decades, there has been a significant growth in the use of natural products, with approximately 80% of individuals using them for some aspect of primary healthcare.
Aida Calderon-Rivera, Kimberly Gomez, Santiago Loya-López, E.M. Kithsiri Wijeratne, Harrison Stratton, Cheng Tang, Paz Duran, Kyleigh Masterson, Omar Alsbiei, A.A. Leslie Gunatilaka, Rajesh Khanna   +10 more
doaj   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

Phytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi, LuLu Zhang, Lan Yan, Qi Geng, Li Li, Xiaojuan He, Ning Zhao, Yong Tan, Xiaomeng Zhang, Cheng Lu   +9 more
wiley   +1 more source

Pharmacological Activity of Betulinic Acid: A Systematic Literature Review [PDF]

, 2023
Betulinic acid comes from betulin, a triterpenoid compound that naturally occurs in the bark of the Betula tree. Betulin has a pentacyclic chemical structure, which contains five distinct rings.
Nayla Robiatul Adawiyah, Surya Amal, Adawiyah, Nayla Robiatul, Himyatul Hidayah   +3 more
core   +1 more source