Results 21 to 30 of about 2,513,921 (167)

Isolation of Betulinic Acid, its Methyl Ester and Guaiane Sesquiterpenoids with Protein Tyrosine Phosphatase 1B Inhibitory Activity from the Roots of Saussurea lappaC.B.Clarke

open access: yesMolecules, 2009
Activity-guided fractionation of a MeOH extract of the roots of Saussurea lappa C.B.Clarke (Compositae), using an in vitro protein tyrosine phosphatase 1B (PTP1B) inhibition assay, led to the isolation of four active constituents: betulinic acid (1 ...
MinKyun Na   +6 more
doaj   +1 more source

Optimization of Enzymatic Synthesis of Betulinic Acid Amide in Organic Solvent by Response Surface Methodology (RSM)

open access: yesIndonesian Journal of Chemistry, 2019
Optimization of the lipase catalyzed enzymatic synthesis of betulinic acid amide in the presence of immobilized lipase, Novozym 435 from Candida antartica as a biocatalyst was studied.
Nurul Atikah Amin Yusof   +4 more
doaj   +1 more source

Preparations of Betulinic Acid Derivatives [PDF]

open access: yes, 2004
Betulinic acid, 3~hydroxy-lup20(29)-ene-28-oic acid is a pentacyclic triterpene. Esterification reactions of betulinic acid were investigated. Betulinic acid esters such as 3-0-succinyl-betulinic acid, 3-0-(2',2'-dimethylsucciny1)-betulinic acid, 3-0-(
Mohd Ali, Mohd Tajudin
core   +1 more source

Evaluation of Betulin and Betulinic Acid Content in Birch Bark from Different Forestry Areas of Western Carpathians

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2012
In order to evaluate the content of betulin and betulinic acids in Birch barks originating from Western Carpathians, Transylvania (Romania) forests, in relation with the location of birch trees, it was recorded the geographic and vegetation conditions at
Liviu HOLONEC   +4 more
doaj   +1 more source

In silico studies of anti-oxidative and hot temperament-based phytochemicals as natural inhibitors of SARS-CoV-2 Mpro.

open access: yesPLoS ONE, 2023
Main protease (Mpro) of SARS-CoV-2 is considered one of the key targets due to its role in viral replication. The use of traditional phytochemicals is an important part of complementary/alternative medicine, which also accompany the concept of ...
Ramin Naderi Beni   +3 more
doaj   +1 more source

Distribution of betulinic acid in plant kingdom [PDF]

open access: yes, 2014
Betulinic acid (3ß-hydroxy-lup-20(29)-en-28-oic acid) is a ubiquitous pentacyclic triterpenoid found in the plants. It is highly valued for its role in wide array of ailments viz.
Pai, Sandeep Ramchandra, Joshi, R K
core   +1 more source

Synthesis, Characterization of Liposomes Modified with Biosurfactant MEL-A Loading Betulinic Acid and Its Anticancer Effect in HepG2 Cell

open access: yesMolecules, 2019
As a novel natural compound delivery system, liposomes are capable of incorporating lipophilic bioactive compounds with enhanced compound solubility, stability and bioavailability, and have been successfully translated into real-time clinical ...
Qin Shu, Jianan Wu, Qihe Chen
doaj   +1 more source

Enzymatic synthesis of betulinic acid ester [PDF]

open access: yes, 2001
Enzymatic synthesis of betulinic acid ester (3-β-hydroxyl-oley-lup-20(29)-en- 28-oic acid) from betulinic acid and oleic acid in chloroform were investigated. Five commercial lipases (Candida rugosa. Aspergillus niger. Penicillium roquerti.
Chew, Won Yin
core   +1 more source

Betulinic Acid Suppresses Ovarian Cancer Cell Proliferation through Induction of Apoptosis

open access: yesBiomolecules, 2019
Ovarian cancer is one of the leading causes of cancer deaths worldwide in women, and the most malignant cancer among the different gynecological cancers.
Dahae Lee   +6 more
doaj   +1 more source

Glycosidation of betulinic acid using novozyme 435 [PDF]

open access: yes, 2016
In this study, 3-O-β-D-glucopyranoside-betulinic acid was successfully synthesized via the reaction between betulinic acid and glucose catalyzed by immobilized lipase from Candida antarctica (Novozyme 435) in t-butanol.
Abdu, Hamisu
core   +1 more source

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