Results 71 to 80 of about 2,513,921 (167)
ABSTRACT The role of microbes in cancer is gaining attention these days, especially in the context of tumor‐associated biofilms and dysbiotic microbiota. Biofilm‐producing microorganisms, such as Fusobacterium nucleatum and Helicobacter pylori, trigger oncogenic inflammation and immune evasion in tumor initiation and progression, and in the development
Saikat Mazumder +14 more
wiley +1 more source
Daily supplementation with Ziziphus jujube fruit improved liver enzymes, lipid profile, and hepatic steatosis in patients with non‐alcoholic fatty liver disease (NAFLD), potentially through its antioxidant, anti‐inflammatory, and lipid‐modulating properties.
Ronak Borzooei +4 more
wiley +1 more source
Inhibition of diacylglycerol acyltransferase by betulinic acid from Alnus hirsuta
During the screening for diacylglycerol acyltransferase (DGAT) inhibitors from natural products, the lupane-type triterpenoid betulinic acid was isolated from the methanol extract of Alnus hirsuta.
D H Kim +9 more
core +1 more source
A rapid, two-solvent, HPLC-APCI-MS method was developed to identify and quantify four pentacyclic triterpenes (betulinic acid, ursolic acid, α-amyrin and β-amyrin) in extracts of the neotropical medicinal plant Souroubea sympetala.
Martha Mullally +9 more
doaj +1 more source
Update on Approved Therapies for Dystrophic and Junctional Epidermolysis Bullosa
ABSTRACT Dystrophic epidermolysis bullosa (DEB) and junctional EB (JEB) are severe, bullous genodermatoses induced by mutations of genes encoding structural skin proteins that disrupt epidermal adhesion. Until recently, treatment was limited to symptomatic care. Since 2022, three therapies – birch triterpenes gel (Filsuvez), beremagene geperpavec‐svdt (
Alberto Pappalardo +5 more
wiley +1 more source
The synthesis of new ester derivatives of betulin (3a-c) and betulinic acid (4) with conjugated linoleic acid isomers (CLA; in a mixture of 43.4% 9c, 11t; 49.5% 10 t , 12 c ; 7.1% other isomers) is presented.
Barbara Tubek +5 more
doaj +1 more source
Constituintes químicos de Hyptidendron canum (Pohl ex Benth.) R. Harley (Lamiaceae)
Chemical investigation of Hyptidendron canum stems resulted in the isolation of betulinic, ursolic and euscaphic acids. From the leaves were isolated 3β-O-β-galactopiranosilsitosterol, ursolic aldehyde, and mixtures of maslinic acid and 2α-hydroxyursolic
Geralda de Fátima Lemes +2 more
doaj +1 more source
Phytochemical investigation of the stem bark of Lonchocarpus laxiflorus yielded three new cassane diterpenoids, lonchocassane A [cassa-13 (14), 15-dien-18, 20-dioic acid], lonchocassane B [cassa-13 (14), 15-dien-20-oxo-18-oic acid] and lonchocassane C ...
John O. Igoli +4 more
doaj +1 more source
Enzymatic Esterification of Betulinic Acid
Esterification of betulinic acid with 1-decanol in chloroform was described. It gave the desired betulinic acid ester. The esterification as expected occurred at C-28 position.
F.H, Ahmad +4 more
core
Effects of Betulinic Acid Alone and in Combination with Irradiation in Human Melanoma Cells [PDF]
Recently, betulinic acid was identified as a highly selective inhibitor of human melanoma growth and was reported to induce apoptosis in these cells. We have investigated the growth-inhibitory properties of this compound alone and in combination with ...
Wacheck, Volker +6 more
core +1 more source

