Results 81 to 90 of about 22,851 (287)

Beneficial Role of Tetrahydrobiopterin on Various Cardiovascular Diseases and Regulation of its Levels under Pathological Conditions

Pteridines, 2006
5,6,7,8-Tetrahydrobiopterin (BH4) is an csscntial cofactor for production of nitric oxide (NO) by N O synthase (NOS). Nitric oxide (NO) is an important signaling mo!ecu!e for the regulation o f vita! functions such as vascular tone, neurotransmission and
Shimizu Shunichi, Ishii Masakazu, Wajima Teruaki, Hagiwara Tamio, Negoro Takaharu   +4 more
doaj   +1 more source

Tetrahydrobiopterin deficiency in schizophrenia as a new target for personalized medicine

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2020
Summary. Tetrahydrobiopterin (BH4) is an important cofactor, that involved in the synthesis of dopamine, norepinephrine, and serotonin, as well as affecting the production of nitric oxide (NO) and regulating the activity of the glutamatergic system.
I. V. Semennov, Y. S. Zagryazhskaya, A. S. Piatoikina, T. V. Zhilyaeva, E. A. Manakova A., A. S. Blagonravova, E. V. Verbitskaya, G. E. Mazo   +7 more
doaj   +1 more source

Genotype frequency of black hull locus (Bh4) in weedy rice (Oryza sativa f. spontanea) populations [PDF]

Research & Knowledge, 2016
Black hull 4 (Bh4), is a hull color candidate gene that causes a black pigmentation in the ripened hulls of rice. A 22-bp deletion within exon 3 of the Bh4 variant disrupted the Bh4 function, which lead to a straw-white hull in Asian cultivated rice and ...
Preecha Prathepha
doaj   +1 more source

Nitrogen Anchoring Effect Triggering Improved Reversible Hydrogen Storage of Mg(BH4)2

This research uncovered the influence of nitrogen-doped MXene Ti3CN on the reversible hydrogen storage properties of Mg(BH4)2. The Mg(BH4)2-20Ti3CN composite began releasing hydrogen at a temperature of 80°C.
Ge, Lei, Lv, Mei‐Ling, Zheng, Jia‐Guang, Li, Cong, Wu, Chang‐Hai, Zhou, Pan‐Pan, Su, Chao, Ma, Zhen‐Xuan   +7 more
core   +1 more source

Thermal Polymorphism and Decomposition of Y(BH4)(3)

, 2010
The structure and thermal decomposition of Y(BH4)(3) is studied by in situ synchrotron radiation powder X-ray diffraction (SR-PXD), B-11 MAS NMR spectroscopy, and thermal analysis (thermogravimetric analysis/differential scanning calorimetry).
Ravnsbaek, Dorthe B., Ravnsbæk, Dorthe B., Ley, Morten B., Filinchuk, Yaroslav, Jensen, Torben R., Ley, Morlen B., Haase, Dörthe, Haase, Dörthe,, Lund University., Cerny, Radovan, Jakobsen, Hans J., Skibsted, Jorgen, Dorthe B. Ravnsbæk, Yaroslav Filinchuk, Torben R. Jensen, Morten B. Ley, Dörthe Haase, Hans J. Jakobsen, Radovan Černý, Jo̷rgen Skibsted   +19 more
core   +1 more source

Tetrahydrobiopterin as a rheostat of cell resistance to oxidant injury

Redox Biology
Tetrahydrobiopterin (BH4) deficiency is caused by genetic abnormalities that impair its biosynthesis and recycling, which trigger neurochemical, metabolic, and redox imbalances.
R. Steven Traeger, James Woodcock, Sidhartha Tan, Zhongjie Shi, Jeannette Vasquez-Vivar   +4 more
doaj   +1 more source

Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH4 Pathway

ACS Omega, 2019
Tetrahydrobiopterin (BH4) is a cofactor in the production of various signaling molecules including nitric oxide, dopamine, adrenaline, and noradrenaline.
B. J. R. Moore, Barira Islam, Sean Ward, Olivia Jackson, Rebecca Armitage, Jack W. D. Blackburn, S. Haider, P. McHugh   +7 more
semanticscholar   +1 more source

A quasielastic and inelastic neutron scattering study of the alkaline and alkaline-earth borohydrides LiBH4 and Mg(BH4)2 and the mixture LiBH4 + Mg(BH4)2.

Physical Chemistry, Chemical Physics - PCCP, 2019
Quasielastic neutron scattering was used to investigate the low energy transfer dynamics of the complex borohydrides Mg(BH4)2 in the α- and β-modifications, LiBH4 in the low and high temperature crystal structure, and an 1 : 1 molar mixture of LiBH4 + α ...
L. Silvi, Z. Zhao-Karger, E. Röhm, M. Fichtner, W. Petry, W. Lohstroh   +5 more
semanticscholar   +1 more source

TAT‐BH4 counteracts Aβ toxicity on capillary endothelium [PDF]

FEBS Letters, 2007
Oxidative stress is one of the factor contributing to blood brain barrier degeneration. This phenomenon is observed during pathological conditions such as Alzheimer's disease or cerebral amyloid angiopathy in which brain haemorrhages are very frequent.
CANTARA, SILVIA, THORPE PE, ZICHE, MARINA, DONNINI, SANDRA   +3 more
openaire   +5 more sources

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source