Results 41 to 50 of about 32,113 (221)
Genome-wide analysis of the bHLH gene family in Chinese jujube (Ziziphus jujuba Mill.) and wild jujube. [PDF]
The bHLH (basic helix-loop-helix) transcription factor is one of the largest families of transcription factors in plants, containing a large number of members with diverse functions. Chinese jujube (Ziziphus jujuba Mill.) is the species with the highest economic value in the family Rhamnaceae.
Li H +8 more
europepmc +5 more sources
Additional file 1 of Automatic annotation of the bHLH gene family in plants
Additional file 1: Detailed description of the identification of highly diverged bHLH sequences and the optimization process of the classification ...
Thoben, Corinna, Pucker, Boas
openaire +1 more source
Characterization of the basic helix–loop–helix gene family and its tissue-differential expression in response to salt stress in poplar [PDF]
The basic helix–loop–helix (bHLH) transcription factor gene family is one of the largest gene families and extensively involved in plant growth, development, and stress responses. However, limited studies are available on the gene family in poplar.
Kai Zhao +5 more
doaj +2 more sources
The basic helix-loop-helix (bHLH) transcription factors (TFs) play crucial regulatory roles in plant responses to abiotic stress. However, their molecular evolution and functions in facultative crassulacean acid metabolism (CAM) plants, Mesembryanthemum ...
Yingchao Zhang +8 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The bHLH gene family, one of the most abundant transcription factor families in plants, plays crucial roles in stress resistance, growth, and development.
Jiali Ye +6 more
doaj +1 more source
Conservation and divergence of bHLH genes in the calcisponge Sycon ciliatum
Background Basic Helix-Loop-Helix (bHLH) genes encode a large family of eukaryotic transcription factors, categorized into six high-order groups: pan-eukaryotic group B involved in regulation of cell cycle, metabolism, and development; holozoan-specific ...
Sofia A. V. Fortunato +3 more
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The basic helix-loop-helix (bHLH) transcription factor family is the second-largest family in plants, where it plays essential roles in development, and the responses to multiple abiotic and biotic stressors.
Yanyan Wu +6 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source

