Results 121 to 130 of about 11,411 (182)

Monoclonal Antibody 5F1 Modulates Formyl Peptide Receptor 1 Conformation for Transmembrane Signaling

FASEB BioAdvances
Formyl peptide receptor 1 (FPR1) is a G protein‐coupled receptor (GPCR) that mediates chemotaxis and bactericidal activities in phagocytes. The monoclonal antibody 5F1 is generated against full‐length FPR1 and used widely for detection of FPR1 expression.
Yue Wang, Yezhou Liu, Yixin Chang, Richard D. Ye   +3 more
doaj   +1 more source

Quantitative Systems Pharmacology and Biased Agonism at Opioid Receptors: A Potential Avenue for Improved Analgesics. [PDF]

Int J Mol Sci, 2022
Bedini A, Cuna E, Baiula M, Spampinato S.   +3 more
europepmc   +1 more source

Structural Insights into Ligand-Receptor Interactions Involved in Biased Agonism of G-Protein Coupled Receptors. [PDF]

Molecules, 2021
Jóźwiak K, Płazińska A.
europepmc   +1 more source

Editorial: Recent Advances in G Protein-Coupled Receptor Signalling: Impact of Intracellular Location, Environment and Biased Agonism. [PDF]

Front Pharmacol, 2021
Halls ML, Davenport AP, Summers RJ.
europepmc   +1 more source

Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System. [PDF]

Molecules, 2022
Moore GJ, Ridgway H, Kelaidonis K, Chasapis CT, Ligielli I, Mavromoustakos T, Bojarska J, Matsoukas JM.   +7 more
europepmc   +1 more source

Novel glucagon-like peptide-1 analogue exhibits potency-driven G-protein biased agonism with promising effects on diabetes and diabetic dry eye syndrome. [PDF]

Bioengineered, 2022
Hao Y, Wei M, Zhang N, Zhang X.
europepmc   +1 more source

Legumain Induces Oral Cancer Pain by Biased Agonism of Protease-Activated Receptor-2. [PDF]

J Neurosci, 2021
Tu NH, Jensen DD, Anderson BM, Chen E, Jimenez-Vargas NN, Scheff NN, Inoue K, Tran HD, Dolan JC, Meek TA, Hollenberg MD, Liu CZ, Vanner SJ, Janal MN, Bunnett NW, Edgington-Mitchell LE, Schmidt BL.   +16 more
europepmc   +1 more source

Serotonin 5-HT_2C Receptor Signaling Analysis Reveals Psychedelic Biased Agonism. [PDF]

ACS Chem Neurosci
Bonniwell EM, Alabdali R, Hennessey JJ, McKee JL, Cavalco NG, Lammers JC, Moore EJ, Franchini L, Orlandi C, McCorvy JD.   +9 more
europepmc   +1 more source

Methodical Challenges and a Possible Resolution in the Assessment of Receptor Reserve for Adenosine, an Agonist with Short Half-Life [PDF]

, 2018
Erdei, Tamás Dániel, Gesztelyi, Rudolf, Juhász, Béla, Lampé, Nóra, Papp, Csaba, Pintér, Ákos, Szabó, Katalin, Szentmiklósi, József András, Szilvássy, Zoltán, Zsuga, Judit   +9 more
core   +1 more source

Evaluating biased agonism of glucagon-like peptide-1 (GLP-1) receptors to improve cellular bioenergetics: A systematic review. [PDF]

Diabetes Obes Metab
Wong S, Le GH, Dri CE, Teopiz KM, McIntyre RS.   +4 more
europepmc   +1 more source