Results 141 to 150 of about 11,411 (182)

Biased Agonism at Nociceptin/Orphanin FQ Receptors: A Structure Activity Study on N/OFQ(1-13)-NH₂. [PDF]

J Med Chem, 2020
Pacifico S, Ferrari F, Albanese V, Marzola E, Neto JA, Ruzza C, Calò G, Preti D, Guerrini R.   +8 more
europepmc   +1 more source

Biased agonism of protease-activated receptor-1 regulates thromboinflammation in murine sickle cell disease. [PDF]

Blood Adv
Ramadas N, Lowder K, Dutton J, Trebak F, Faes C, Griffin JH, Pawlinski R, Mosnier LO, Sparkenbaugh E.   +8 more
europepmc   +1 more source

Functional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism. [PDF]

J Biol Chem
Rodriguez P, Laskowski LJ, Pallais JP, Bock HA, Cavalco NG, Anderson EI, Calkins MM, Razzoli M, Sham YY, McCorvy JD, Bartolomucci A.   +10 more
europepmc   +1 more source

Assessment of Biased Agonism among Distinct Synthetic Cannabinoid Receptor Agonist Scaffolds. [PDF]

ACS Pharmacol Transl Sci, 2020
Wouters E, Walraed J, Robertson MJ, Meyrath M, Szpakowska M, Chevigné A, Skiniotis G, Stove C.   +7 more
europepmc   +1 more source

Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. [PDF]

Nat Commun
Yadav MK, Sarma P, Maharana J, Ganguly M, Mishra S, Zaidi N, Dalal A, Singh V, Saha S, Mahajan G, Sharma S, Chami M, Banerjee R, Shukla AK.   +13 more
europepmc   +1 more source

Assessment of biased agonism at the A₃ adenosine receptor using β-arrestin and miniGα_i recruitment assays. [PDF]

Biochem Pharmacol, 2020
Pottie E, Tosh DK, Gao ZG, Jacobson KA, Stove CP.   +4 more
europepmc   +1 more source

Biased agonism and opioid receptor-mediated analgesia

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2018
openaire   +2 more sources

Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. [PDF]

J Am Chem Soc, 2019
Liu S, Jean-Alphonse FG, White AD, Wootten D, Sexton PM, Gardella TJ, Vilardaga JP, Gellman SH.   +7 more
europepmc   +1 more source

New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism. [PDF]

Br J Pharmacol, 2018
Vecchio EA, Baltos JA, Nguyen ATN, Christopoulos A, White PJ, May LT.   +5 more
europepmc   +1 more source

G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons. [PDF]

Sci Signal, 2018
Ho JH, Stahl EL, Schmid CL, Scarry SM, Aubé J, Bohn LM.   +5 more
europepmc   +1 more source