Results 131 to 140 of about 185,950 (192)

Targeting the Angiotensin II Type 1 Receptor in Cerebrovascular Diseases: Biased Signaling Raises New Hopes. [PDF]

Int J Mol Sci, 2021
Delaitre C, Boisbrun M, Lecat S, Dupuis F.   +3 more
europepmc   +1 more source

Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma. [PDF]

Cell Rep
Sadeghi M, Salama MF, Chiappone SB, Huang A, Resnick AE, Kandpal M, Clarke CJ, Haley JD, Davuluri RV, Hannun YA.   +9 more
europepmc   +1 more source

Kinome profiling: A veritable Rosetta Stone for protease-activated receptor 1 biased signaling. [PDF]

Vascul Pharmacol
Rajala R, Griffin CT.
europepmc   +1 more source

Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats [PDF]

, 2018
Bové, Calastretti, Carloni, Castedo, Castedo, Chauhan, Chen, Chong, Chong, Donnan, Ferri, Flynn, Fu, Genova, Harada, Hwang, Hwang, Jiang, Kofman, Koh, Li, Li, Lu, Lu, Maiese, Rieker, Sanghera, Santini, Schmued, Shahjouei, Siddiqui, Thyrell, Urbanek, Wang, Wang, Wechsler, Wong, Xie, Xie, Yang, Yin, Zare, Zeng   +42 more
core   +2 more sources

Unconventional receptor functions and location-biased signaling of the lactate GPCR in the nucleus. [PDF]

Life Sci Alliance
Mohammad Nezhady MA, Cagnone G, Bajon E, Chaudhari P, Modaresinejad M, Hardy P, Maggiorani D, Quiniou C, Joyal JS, Beauséjour C, Chemtob S.   +10 more
europepmc   +1 more source

Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor. [PDF]

Nat Chem, 2022
Yen HY, Liko I, Song W, Kapoor P, Almeida F, Toporowska J, Gherbi K, Hopper JTS, Charlton SJ, Politis A, Sansom MSP, Jazayeri A, Robinson CV.   +12 more
europepmc   +1 more source

Agonists of the Nuclear Receptor PPARγ Can Produce Biased Signaling. [PDF]

Mol Pharmacol
Rayl ML, Nemetchek MD, Voss AH, Hughes TS.   +3 more
europepmc   +1 more source

Advances in calcium-sensing receptor modulation: biased signaling and therapeutic potential. [PDF]

Signal Transduct Target Ther
Uhlmann L, Wagner U.
europepmc   +1 more source

An activating calcium-sensing receptor variant with biased signaling reveals a critical residue for Gα11 coupling. [PDF]

J Bone Miner Res
Benson MR, Wyatt RA, Levine MA, Gorvin CM.   +3 more
europepmc   +1 more source

Biased Signaling Agonists Promote Distinct Phosphorylation and Conformational States of the Dopamine D3 Receptor. [PDF]

Int J Mol Sci
Nepal B, Barnett J, Bearoff F, Kortagere S.   +3 more
europepmc   +1 more source