Biginelli reaction catalyzed by copper nanoparticles. [PDF]
PLoS ONE, 2012 We recently reported a novel synthesis of copper nanoparticles from copper sulphate utilizing the charge-compensatory effect of ionic liquid [bmim]BF(4) and ethylene glycol. The nanoparticles were characterized and found to be stable for one year.
Manika Dewan +4 more
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Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction [PDF]
MoleculesThe relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric ...
Marcos Díaz-Fernández +5 more
doaj +6 more sources
Stepping Further from Coupling Tools: Development of Functional Polymers via the Biginelli Reaction [PDF]
Molecules, 2022 Multicomponent reactions (MCRs) have been used to prepare polymers with appealing functions. The Biginelli reaction, one of the oldest and most famous MCRs, has sparked new scientific discoveries in polymer chemistry since 2013.
Zeyu Ma, Bo Wang, Lei Tao
doaj +3 more sources
Efficient One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones via a Three-Component Biginelli Reaction [PDF]
Molecules, 2021 Multicomponent reactions are considered to be of increasing importance as time progresses due to the economic and environmental advantages such strategies entail.
Giovanna Bosica +3 more
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High-Shear Enhancement of Biginelli Reactions in Macromolecular Viscous Media. [PDF]
Macromol Rapid CommunBiginelli reactions are important multicomponent reactions in macromolecular chemistry. it is demonstrated that by using the vortex fluidic device (VFD) Biginelli reactions can be completed at room temperature in just 1 h. However, the critical need to understand solution viscosity as a function of macromolecular chain length to better understand ...
Bui AH +5 more
europepmc +3 more sources
Synthesis of diverse dihydropyrimidine-related scaffolds by fluorous benzaldehyde-based Biginelli reaction and post-condensation modifications [PDF]
Beilstein Journal of Organic Chemistry, 2011 Dihydropyrimidinones and dihydropyrimidinethiones generated from the Biginelli reactions of perfluorooctanesulfonyl-attached benzaldehydes are used as common intermediates for post-condensation modifications such as cycloaddition, Liebeskind–Srogl ...
Bruno Piqani, Wei Zhang
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A copper-doped ZIF-8: a high-performance catalyst for eco-friendly Ullmann and Biginelli reactions [PDF]
Scientific ReportsMetal-organic frameworks (MOFs) with high porosity have gained significant interest in organic reactions. In this study, copper-doped ZIF-8 (Cu-ZIF-8) was synthesized at room temperature, followed by oven drying at 60 °C, and subsequently employed as a ...
Zahra Doraghi +2 more
doaj +3 more sources
Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation. [PDF]
Molecules, 2022 Novel multitarget-directed ligands BIGI 4a-d and BIGI 5a-d were designed and synthesized with a simple and cost-efficient procedure via a one-pot three-component Biginelli reaction targeting acetyl-/butyrylcholinesterases inhibition, calcium channel ...
Malek R +12 more
europepmc +2 more sources
Biginelli Reaction Mediated Synthesis of Antimicrobial Pyrimidine Derivatives and Their Therapeutic Properties. [PDF]
Molecules, 2021 Antimicrobial resistance was one of the top priorities for global public health before the start of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical landscape due to COVID-19, finding new organic structures with antimicrobial ...
Marinescu M.
europepmc +2 more sources
Synthesis of 3,4-Dihydropyrimidin(thio)one Containing Scaffold: Biginelli-like Reactions [PDF]
Pharmaceuticals, 2022 The interest in 3,4-dihydropyrimidine-2(1H)-(thio)ones is increasing every day, mainly due to their paramount biological relevance. The Biginelli reaction is the classical approach to reaching these scaffolds, although the product diversity suffers from ...
Francisco Sánchez-Sancho +6 more
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