Biginelli reaction catalyzed by copper nanoparticles. [PDF]
PLoS ONE, 2012 We recently reported a novel synthesis of copper nanoparticles from copper sulphate utilizing the charge-compensatory effect of ionic liquid [bmim]BF(4) and ethylene glycol. The nanoparticles were characterized and found to be stable for one year.
Manika Dewan +4 more
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Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction [PDF]
MoleculesThe relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric ...
Marcos Díaz-Fernández +5 more
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Stepping Further from Coupling Tools: Development of Functional Polymers via the Biginelli Reaction [PDF]
Molecules, 2022 Multicomponent reactions (MCRs) have been used to prepare polymers with appealing functions. The Biginelli reaction, one of the oldest and most famous MCRs, has sparked new scientific discoveries in polymer chemistry since 2013.
Zeyu Ma, Bo Wang, Lei Tao
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Efficient One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones via a Three-Component Biginelli Reaction [PDF]
Molecules, 2021 Multicomponent reactions are considered to be of increasing importance as time progresses due to the economic and environmental advantages such strategies entail.
Giovanna Bosica +3 more
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Synthesis of structurally diverse 3,4-dihydropyrimidin-2(1H)-ones via sequential Biginelli and Passerini reactions [PDF]
Beilstein Journal of Organic Chemistry, 2017 The Biginelli reaction was combined with the Passerini reaction for the first time in a sequential multicomponent tandem reaction approach. After evaluation of all possible linker components and a suitable solvent system, highly functionalized ...
Andreas C. Boukis +2 more
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Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation. [PDF]
Molecules, 2022 Malek R +12 more
europepmc +3 more sources
Current progress in asymmetric Biginelli reaction: an update [PDF]
Molecular Diversity, 2018 The Biginelli reaction, involving a three-component reaction of an aromatic aldehyde, urea and ethyl acetoacetate, has emerged as an extremely useful synthetic tool to organic chemists for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones and related heterocyclic compounds. In the past decades, the asymmetric variants of this reaction have been at the
Majid M. Heravı +3 more
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Organocatalytic Asymmetric Biginelli-like Reaction Involving Isatin
The Journal of Organic Chemistry, 2016 The first asymmetric, Brønsted acid catalyzed Biginelli-like reaction of a ketone has been developed, employing N-substituted isatins as carbonyl substrates, and urea and alkyl acetoacetates as further components. BINOL-derived phosphoric acid catalysts have been used to achieve the synthesis of a small library of chiral, enantioenriched spiro(indoline-
Mattia Stucchi +5 more
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A Five-Component Biginelli-Diels-Alder Cascade Reaction [PDF]
Frontiers in Chemistry, 2018 A new multi-component condensation was discovered during the reaction of a urea, β-keto ester, and formaldehyde. In the presence of catalytic indium bromide, a Biginelli dihydropyrimidinone intermediate was further converted to a five-component ...
Taber S. Maskrey +3 more
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Biginelli Type Reaction with Tetroses Derivatives
HETEROCYCLES, 1988 Reaction de O-ethylidene-2,4 erythrose et -threose avec l'acetylacetate de methyle, l'uree et la thiouree; obtention principalement d'analogues de nucleosides ...
Marı́a Valpuesta +2 more
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