Results 121 to 130 of about 4,540 (259)

Revisiting the structure and chemistry of 3(5)-Substituted Pyrazoles [PDF]

, 2019
Pyrazoles are known as versatile scaffolds in organic synthesis and medicinal chemistry, often used as starting materials for the preparation of more complex heterocyclic systems with relevance in the pharmaceutical field.
Alam, Alina Secrieru, Alkorta, Andes, Anwar, Behr, Brown, Castillo, Catalan, Chauhan, Clark, Elguero, Elnagdi, Favre, Fichez, Hall, Horta, Katritzky, Katritzky, Kost, Kumar, Larina, Maria Lurdes Santos Cristiano, Mert, Minkin, Minkin, Mohamed, Nagy, Nimbalkar, Paul Michael O’Neill, Schofield, Simons, Szajda, Taylor, Zerbi   +34 more
core   +2 more sources

Reações multicomponentes de Biginelli e de Mannich nas aulas de química orgânica experimental: uma abordagem didática de conceitos da química verde

Química Nova, 2012
The introduction of Mannich and Biginelli multicomponent reactions in a practical Organic Chemistry course is presented in this article. Procedures described in the literature were adapted for use under the simple conditions available in undergraduate ...
Marcelo Volpatto Marques, Tula Beck Bisol, Marcus Mandolesi Sá   +2 more
doaj   +1 more source

Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids [PDF]

, 2014
Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively.
Carda, Miguel, Cardona G, Wilson I, Otero, Elver, Otálvaro, Felipe, Robledo, Sara M., Rojas, Carlos, Vergara, Sebastián, Vélez, Iván D.   +7 more
core   +2 more sources

Modified Biginelli Reaction: Synthesis of Pyrimidoquinoline Derivatives

Asian Journal of Chemistry, 2019
Compounds having quinolone and pyrimidine skeleton plays an important role in the medicinal chemistry. The objective of the present work was to modify the Biginelli reaction by using heterocylic ketones under microwave condition. We have demonstrated new synthetic route of quinolone fused 1,4-dipyrimidines by the reaction of 6-methyl-4-hyrdoxyquinolin ...
V. NADARAJ, S. THAMARAI SELVI, M. ABIRAMI   +2 more
openaire   +1 more source

Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate

Molbank, 2009
Methyl 6-methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate has been synthesized via Biginelli reaction of 4-iodobenzaldehyde, methyl acetoacetate and thiourea, promoted by microwave irradiation in the presence of iodine under ...
Qingjian Liu, Ning Pan, Wenwen Zhang
doaj   +1 more source

A Brønsted acidic ionic liquid anchored to magnetite nanoparticles as a novel recoverable heterogeneous catalyst for the Biginelli reaction. [PDF]

RSC Adv, 2021
Oboudatian HS, Naeimi H, Moradian M.
europepmc   +1 more source

Polymer-Supported Dioxidovanadium(V) Complex-Based Heterogeneous Catalyst for Multicomponent Biginelli Reaction Producing Biologically Active 3,4-Dihydropyrimidin-2-(1H)-ones [PDF]

, 2023
Mannar R. Maurya, Akhil Patter, Devesh Kumar Singh, Kaushik Ghosh   +3 more
openalex   +1 more source

Synthesis of arylpiridines with us on bifuntional catalysts Me/SiO2-SO3H (Me= Au, Ir, Pt) [PDF]

, 2016
Se estudió la reacción multicomponente de Hantzsch para la obtención de compuestos derivados de la familia 2-arilpiridinas, usando catalizadores bifuncionales tipo Me/SiO2-SO3H (Me = Au, Pt, Ir). Los catalizadores se caracterizaron por distintas técnicas
Martinez, José, Nope Vargas, Eliana Rocio, Rojas, Hugo, Romanelli, Gustavo Pablo, Sathicq, Angel Gabriel   +4 more
core  

Tungsten-substituted molybdophosphoric acid impregnated with kaolin: effective catalysts for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones via biginelli reaction. [PDF]

RSC Adv, 2021
Aher DS, Khillare KR, Chavan LD, Shankarwar SG.   +3 more
europepmc   +1 more source

Design, synthesis and biological Evaluation of novel chromones having 3,4-dihydropyrimidin-2(1H)-one core at C-8 in combination with triazoles: New α-glucosidase inhibitors and anti-bacterial agents

European Journal of Medicinal Chemistry Reports
The Biginelli reaction synthesizes dihydropyrimidones through a multi-component reaction. A β-ketoester, aldehyde, and urea or thiourea react in the presence of an acid catalyst to form these dihydropyrimidones.
Kumara Swamy Taviti, T.B. Patrudu, Nagalakshmi Jeedimalla, Naresh Kumar Katari, Satyanarayana Yatam, Rambabu Gundla   +5 more
doaj   +1 more source