Results 121 to 130 of about 1,846 (154)

The Biginelli Reaction

Journal of Chemical Education, 2001
The utilization of the Biginelli reaction, a one-pot condensation of an aldehyde, a β-keto ester, and urea, is described. This reaction involves a number of individual steps, each of which is accessible to first-year organic students. The product, a 3,4-dihydropyrimidinone, is a member of a medicinally useful class of compounds.
Michael S. Holden, R. David Crouch
openaire   +1 more source

Recent progress in asymmetric Biginelli reaction

Molecular Diversity, 2013
The Biginelli reaction, which involves the interaction of ethyl acetoacetate, urea, and an appropriate aryl aldehyde, was first discovered by Pietro Biginelli about 120 years ago. The Biginelli products (3,4-dihydropyrimidin-2(1H)-ones) are interesting materials due to their significant pharmacological and structural profiles.
Majid M, Heravi   +2 more
openaire   +2 more sources

Biginelli reaction: an overview

Tetrahedron Letters, 2016
Abstract Biginelli reaction involves acid-catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) using easily-accessible starting materials, namely, aldehyde, active methylene compound and (thio)urea. DHPMs have stimulated resurgence of interest in the past two decades due to their wide ranging pharmacological activities and presence ...
Honnappa Nagarajaiah   +2 more
openaire   +1 more source

Tandem Hydroformylation-Biginelli Reaction

Synlett, 2013
The combination of a tandem process with a multicomponent reaction is a new approach to high atom-economic synthesis. A tandem hydroformylation–Biginelli reaction sequence has been developed leading to a variety of functionalized 4-alkyl-substituted 3,4-dihydropyrimidin-2(1H)-ones.
Fuchs, Daniela   +4 more
openaire   +2 more sources

ChemInform Abstract: Biginelli Reaction

ChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Anil Saini   +2 more
openaire   +1 more source

Biginelli Reaction: Polymer Supported Catalytic Approaches

ACS Combinatorial Science, 2019
The Biginelli product, dihydropyrimidinone (DHPM) core, and its derivatives are of immense biological importance. There are several methods reported as modifications to the original Biginelli reaction. Among them, many involve the use of different catalysts.
Rajendra V. Patil   +4 more
openaire   +2 more sources

2‐Phenacylbenzothiazole in the Biginelli Reaction.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
I. B. Dzvinchuk   +2 more
openaire   +1 more source

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