Ethyl 4-[5-(methoxymethyl)furan-2-yl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
A one-pot multicomponent reaction has been used to synthesize the title compound, ethyl 4-[5-(methoxymethyl)furan-2-yl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate by PTSA catalyzed Biginelli reaction.
Hery Suwito +4 more
doaj +1 more source
A versatile and an efficient synthesis of 5-substituted-1H-tetrazoles [PDF]
A simple, efficient and a versatile method for the synthesis of 5-substituted-1H-tetrazoles by a [3+2]-cycloaddn. reaction of aryl nitriles with sodium azide in DMF using ZrOCl2·8 H2O as catalyst has been developed. The reactions work well at 100°C
Gowd Madhusudana Reddy Muthukur Bhoje, . +1 more
core +1 more source
Catalysis With Deep Eutectic Solvents: Challenges and Opportunities
Deep eutectic solvents (DESs) are emerging as sustainable alternatives in catalysis, offering tunable properties for diverse chemical transformations. This review explores the dual role of DESs as solvents and catalysts, highlighting advancements in organic chemistry, materials science, CO2 fixation, biomass valorization, polymer degradation, and ...
Eduardo Guzmán
wiley +1 more source
Ferrocén-szubsztituált heterociklusok és származékaik szintézise, szerkezetigazolása és komplex spektroszkópiai vizsgálata = Synthesis, structure determination and complex spectroscopic study of ferrocene-substituted heterocycles and their derivatives [PDF]
Új, mono- és poliheterociklusokkal egyszeresen és többszörösen szubsztituált ferrocénszármazékokat állítottunk elő. Szerkezetüket komplex nagyműszeres vizsgálatokkal (IR, MS, röntgendiffrakció, multinukleáris NMR) derítettük fel.
Csámpai, Antal +4 more
core
Dihydropyrimidinone Based Chromones as New α‐Glucosidase Inhibitors
1‐(2,4‐Dihydroxyphenyl)ethanone functions as a fundamental precursor in the synthesis of dihydropyrimidinone conjugates that incorporate both chromone and triazole moieties. Docking analyses are performed on 15 synthetic compounds. In silico investigations confirm high binding affinity, with docking energies of −10.7 kcal/mol for compound 5a and −10.9 ...
Kumara Swamy Taviti +6 more
wiley +1 more source
A variety of 3,4-dihydropyrimidin-2(1H)-ones derivatives were synthesized via three-component Biginelli reaction. The quaternary ammonium-treated clay-catalyzed process proved to be simple, efficient, and environmentally friendly.
Soheil Sayyahi +2 more
doaj +1 more source
Recent Advances in Biocatalytic Promiscuity: Hydrolase-Catalyzed Reactions for Nonconventional Transformations [PDF]
Financial support from the Spanish Ministerio de Economía y Competitividad (CTQ2013-44153-P) is grateful acknowledged. M.L.-I.
Gotor Fernández, Vicente +1 more
core +2 more sources
A library of novel organochalcogen‐DHPM‐triazole hybrids was developed using a rapid, simple, and ultrasound‐assisted method. Additionally, all compounds underwent comprehensive theoretical, photophysical, and electrochemical characterization, providing relevant insights for future biological applications.
Amanda R. Azevedo +4 more
wiley +1 more source
Cinchona-Derived Picolinamides: Effective Organocatalysts for Stereoselective Imine Hydrosilylation [PDF]
Picolinamide-cinchona organocatalysts for the successful enantioselective reduction of ketomines were developed. For the first time, a new type of chiral Lewis base, a cationic species, is reported to efficiently organocatalyze the addition of ...
Andrea, Genoni +3 more
core +1 more source
A simple and efficient method for the one-pot Biginelli condensation reaction of aldehydes, β-dicarbonyl compounds, and urea or thiourea employing [DABCO](SO3H)2Cl2 as a novel ionic liquid catalyst is described.
Firouzeh Nemati, Sara G. Alizadeh
doaj +1 more source

