A new perspective on metformin therapy in type 1 diabetes [PDF]
Metformin is quite frequently used off-label in type 1 diabetes to limit insulin dose requirement. Guidelines recommend that it can improve glucose control in those who are overweight and obese but evidence in support of this is limited.
Boyle, James G.+2 more
core +1 more source
The Effect of Various Irrigants on Mixed Biofilms in Dentinal Tubules: A Confocal Laser Scanning Microscopy Study. [PDF]
This study evaluated the disinfection efficacy of various irrigation solutions against mixed biofilms in dentinal tubules. The findings of CLSM analysis and viable bacterial sampling revealed that combined irrigation solutions were significantly more effective than single solutions, supporting their use as the preferred approach in clinical practice ...
Tekinarslan D+4 more
europepmc +2 more sources
Early drug use of dapagliflozin prescribed by general practitioners and diabetologists in Germany. [PDF]
OBJECTIVES: Dapagliflozin is an inhibitor of the human sodium-glucose co-transporter 2 (SGLT2) that has been shown to improve glycaemic control in patients with type 2 diabetes mellitus (T2DM).
Hammar, Niklas+3 more
core +1 more source
Antitumor Effects and Mechanisms of Metabolic Syndrome Medications on Hepatocellular Carcinoma
Kyoko Oura, Asahiro Morishita, Joji Tani, Tsutomu Masaki Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kagawa, JapanCorrespondence: Kyoko Oura, Department of Gastroenterology and Neurology, Kagawa University, 1750 ...
Oura K, Morishita A, Tani J, Masaki T
doaj
Does microbicide use in consumer products promote antimicrobial resistance? A critical review and recommendations for a cohesive approach to risk assessment [PDF]
The increasing use of microbicides in consumer products is raising concerns related to enhanced microbicide resistance in bacteria and potential cross resistance to antibiotics.
Bloomfield, Sally+12 more
core +3 more sources
Background and Aims Polyhexamethyl biguanide (PHMB), a widely used topical treatment for Acanthamoeba keratitis (AK), is unlicensed with no formal safety assessment. This study evaluated its safety and tolerability.
V. Papa+7 more
semanticscholar +1 more source
Biguanide-, imine-, and guanidine-based networks as catalysts for transesterification of vegetable oil [PDF]
Polycationic systems based on poly(hexamethylene biguanide) (PHMBG), branched polyethyleneimine (PEI) and poly(N-vinylguanidine) (PVG) have been evaluated as heterogeneous catalysts for the transesterification of sunflower oil by methanol.
Alvarez, Michael+4 more
core +1 more source
In order to endue silk fibroin (SF) sponges with antibacterial function, positively charged poly(hexamethylene biguanide) hydrochloride (PHMB) was incorporated in SF through electrostatic interaction and by freeze-drying technique.
A. Liang+5 more
semanticscholar +1 more source
New poly(ester urea) derived from L-leucine: Electrospun scaffolds loaded with antibacterial drugs and enzymes [PDF]
Electrospun scaffolds from an amino acid containing poly(ester urea) (PEU) were developed as promising materials in the biomedical field and specifically in tissue engineering applications. The selected poly(ester urea) was obtained with a high yield and
Díaz Andrade, Angélica María+4 more
core +2 more sources