Results 61 to 70 of about 9,814 (230)

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Prevention and Management of Driveline Infections in Ventricular Assist Device Patients: The DESTINE 2.0 Staging Proposal and Expert Recommendations

Artificial Organs, EarlyView.
DESTINE 2.0 decision flowchart: stage‐based assessment and management of driveline exit‐site disorders. The flowchart provides a simplified decision‐support tool for the stage‐based evaluation and management of driveline exit‐site disorders in LVAD patients, intended as a practical complement to the staging pyramid (Figre 2) and the detailed staging ...
Alexander M. Bernhardt, Volker Lauenroth, Florian Mueller, Friedrich Kaufmann, Katharina Homann, Martina Socha, Thomas Schlöglhofer, the Driveline Expert STagINg and carE (DESTINE) study group   +7 more
wiley   +1 more source

Phenylethynylbenzyl-modified biguanides inhibit pancreatic cancer tumor growth

Scientific Reports, 2021
We present the design and synthesis of a small library of substituted biguanidium salts and their capacity to inhibit the growth of pancreatic cancer cells.
Audrey Hébert, Maxime Parisotto, Marie-Camille Rowell, Alexandra Doré, Ana Fernandez Ruiz, Guillaume Lefrançois, Paloma Kalegari, Gerardo Ferbeyre, Andreea R. Schmitzer   +8 more
doaj   +1 more source

The Pituitary Gland is a Novel Major Site of Action of Metformin in Non-Human Primates: a Potential Path to Expand and Integrate Its Metabolic Actions

Cellular Physiology and Biochemistry, 2018
Background/Aims: Biguanides are anti-hyperglycaemic agents used to treat diabetes by acting primarily on the liver, inhibiting hepatic gluconeogenesis. However, biguanides may target other key metabolic tissues to exert beneficial actions. As the “master
Mari C. Vázquez-Borrego, Antonio C. Fuentes-Fayos, Manuel D. Gahete, Justo P. Castaño, Rhonda D. Kineman, Raúl M. Luque   +5 more
doaj   +1 more source

Type 2 Diabetes in Neuroendocrine Tumors: Are Biguanides and Statins Part of the Solution?

, 2018
Context Biguanides and statins exert beneficial effects on various cancer types. Their precise effects and underlying molecular mechanisms are poorly understood.
Herrera-Martinez, Aura D, Luque, Raúl M., Castaño, Justo P, Gahete, Manuel D, Galvez-Moreno, Maria A, Pedraza-Arévalo, Sergio, Gahete, Manuel D., Gálvez-Moreno, María A., Castaño, Justo P., Herrera-Martínez, Aura D., L-López, Fernando, Luque, Raul M   +11 more
core   +1 more source

Chlorhexidine 0.02% or polyhexamethylene biguanide 0.02% as the main treatment for Acanthamoeba keratitis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report medical cure and treatment failure rates of Acanthamoeba keratitis (AK) with respect to type of treatment, disease stage and prognostic factors. Methods Electronic records were reviewed for 45 patients with PCR‐positive AK treated at the Department of Ophthalmology, Aarhus University Hospital, Denmark from 2012 to 2025 ...
Anders Ivarsen, Sandra M. Skovdal, Stine Elkjær Nielsen, Christen Rune Stensvold, Henrik Vedel Nielsen, Jesper Hjortdal   +5 more
wiley   +1 more source

Biguanides [PDF]

Diabetologia, 1978
M, Nattrass, K G, Alberti
openaire   +4 more sources

Comparison of decision tree with common machine learning models for prediction of biguanide and sulfonylurea poisoning in the United States: an analysis of the National Poison Data System

BMC Medical Informatics and Decision Making, 2023
Background Biguanides and sulfonylurea are two classes of anti-diabetic medications that have commonly been prescribed all around the world. Diagnosis of biguanide and sulfonylurea exposures is based on history taking and physical examination; thus ...
Omid Mehrpour, Farhad Saeedi, Samaneh Nakhaee, Farbod Tavakkoli Khomeini, Ali Hadianfar, Alireza Amirabadizadeh, Christopher Hoyte   +6 more
doaj   +1 more source

Related Articles / Press Coverage from Metformin and Other Biguanides in Oncology: Advancing the Research Agenda

, 2010
Related Articles / Press Coverage from Metformin and Other Biguanides in Oncology: Advancing the Research ...
Michael Pollak (11169)
core   +1 more source

Mitigating the human link in emerging reptile fungal pathogen transmission

Conservation Biology, EarlyView.
Abstract Handling wild reptiles is common among amateur herpetology enthusiasts, professional researchers, social media influencers, and photographers. However, the potential for these interactions to spread diseases that threaten wild reptiles remains underappreciated.
Patrick S. Champagne, Richelle G. Butcher, Lachlan A. Bourke, Lorenzo Seneci, Laura F. Grogan   +4 more
wiley   +1 more source