Results 271 to 280 of about 368,411 (307)
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Bile acid biosynthesis

Biochemistry, 1992
To conclude, the last several years have seen a resurgence of interest in the biosynthesis of bile acids. This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, and molecular biology.
D W, Russell, K D, Setchell
openaire   +2 more sources

Bile acids LVII. Bile acids and colorectal cancer

Lipids, 1978
AbstractSignificant correlations have been reported by epidemiologists between the mortality from colorectal cancer in various populations and the consumption of meat or lipids by these populations. These have directed considerable attention to possible relationships between diet and the occurrence of this neoplasm.
J W, Davis, W H, Elliott
openaire   +2 more sources

Bile acid malabsorption

Current Treatment Options in Gastroenterology, 2007
Patients with bile acid malabsorption typically present with chronic, watery diarrhea. Bile acids recirculate between the liver and small intestine in the enterohepatic circulation. They are reabsorbed in the distal small intestine, and normally only a small fraction of the bile acid pool is lost to the colon during each cycle.
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Bile acid sulfates in serum bile acids determination

Steroids, 1979
Some bile acid sulfates were synthesized and characterized. The configuration of sulfate groups at C-3, C-7 and C-12 positions was confirmed by Nuclear Magnetic Resonance analysis. These sulfates were utilized in a study of their chemical behaviour in different analytical procedures currently used for serum bile acids determination. Procedures for bile
J F, Pageaux   +3 more
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Bile Acid Diarrhea

Digestive Diseases, 1998
Bile acids normally undergo enterohepatic circulation. When this circulation is interrupted, bile acids enter the colon in increased concentrations. Here, they produce Cl<sup>–</sup> secretion by a calcium- and cyclic AMP-dependent mechanism, resulting in diarrhea.
openaire   +2 more sources

Species differences in bile acids II. Bile acid metabolism

Journal of Applied Toxicology, 2018
AbstractOne of the mechanisms of drug‐induced liver injury (DILI) involves alterations in bile acid (BA) homeostasis and elimination, which encompass several metabolic pathways including hydroxylation, amidation, sulfation, glucuronidation and glutathione conjugation.
Rhishikesh Thakare   +4 more
openaire   +2 more sources

Bile acids. LIV—Mass spectra of conjugated bile acids

Biological Mass Spectrometry, 1978
The electron impact mass spectra of conjugated bile acids, their 5alpha-analogs and methyl esters of glyco conjugates were determined by direct insertion into the ion source and their fragmentation patterns were found to be basically similar to those of methyl esters of the free bile acids. The conjugates are additionally characterized by a significant
R, Shaw, W H, Elliott
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Bile acid separation

Journal of Chromatography B: Biomedical Sciences and Applications, 1995
A review of the methods available for the separation of bile acids is presented, highlighting the most recent developments. The major chromatographic techniques (TLC, GC, HPLC) and combined detection systems for the determination of bile acids are critically evaluated and their advantages and disadvantages discussed.
openaire   +3 more sources

DUODENAL BILE-ACIDS

The Lancet, 1972
D N, Challacombe, S, Edkins
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