Results 271 to 280 of about 5,534,791 (400)

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao, Marie Mostue Naume, Brenda C. M. de Winter, Thomas Krag, Sissel Sundell Haslund‐Krog, Karoline Lolk Revsbech, John Vissing, Helle Holst, Morten Hylander Møller, Tessa Munkeboe Hornsyld, Morten Dunø, Christina Engel Hoei‐Hansen, Alfred Peter Born, Per Bo Jensen, Mette Cathrine Ørngreen   +14 more
wiley   +1 more source

Studies on Bile Salts of Toad (Bufo vulgaris japonicus). XI. Formation of Norcholic Acid from Δ²³-3(α), 7(α), 12(α)-Trihydroxycoprostenic Acid C₂₇H₄₄O₅ and Stem Acid C₂₇H₄₆O₂

, 1953
Shõhei Hayakawa
openalex   +2 more sources

Bile Acids of Elasmobranch Fish [PDF]

, 1941
Janine Cook
openalex   +1 more source

Dysregulation of bile acid signal transduction causes neurological dysfunction in cirrhosis rats. [PDF]

World J Hepatol
Ren C, Cha L, Huang SY, Bai GH, Li JH, Xiong X, Feng YX, Feng DP, Gao L, Li JY.   +9 more
europepmc   +1 more source

The Synthesis of Stero-bile Acid. VI. The Synthesis of Trihydroxycoprostane

, 1954
Taro Kazuno, A. Mori
openalex   +2 more sources

A comparison of some methods for the determination of bile acids in bile, and the proportion between the different acids [PDF]

, 1936
Bertil Josephson, Gunnar Jungner
openalex   +1 more source

Calorie restriction plugs lithocholic bile acid into the lysosomal AMPK pathway. [PDF]

Life Metab
Viollet B.
europepmc   +1 more source

Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells remain the industry standard for producing numerous therapeutic proteins, particularly monoclonal antibodies (mAbs). However, achieving higher recombinant protein titers remains an ongoing challenge and a fundamental understanding of the cellular mechanism driving improved bioprocess performance remains ...
Kate E. Meeson, Joanne Watson, Susan Rosser, Ellie Hawke, Andrew Pitt, Tessa Moses, Leon Pybus, Magnus Rattray, Alan J. Dickson, Jean‐Marc Schwartz   +9 more
wiley   +1 more source

The Synthesis of Stero-bile Acids. XV

, 1955
K. Fuziwara
openalex   +2 more sources

Quantitive Determination of Bile Acids on Paper Chromatograms. [PDF]

, 1954
Sten Eriksson, Jan Sjövall, Maunu Merikallio, Paavo Pääkkönen, Oiva Järvelä   +4 more
openalex   +1 more source