Results 181 to 190 of about 3,456,901 (302)

Enhancing Hepatic Antioxidant Capacity and Carbohydrate, Lipid, and Bile Acid Metabolism in Largemouth Bass Through Dietary Betaine Supplementation. [PDF]

Antioxidants (Basel)
Lin J, Yang M, Huang Q, Zhang L, Lu L, Zhang C, Jiang J.   +6 more
europepmc   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Cold exposure remodels bile acid metabolism in a mouse strain- and tissue-specific manner. [PDF]

Biochem J
Beji S, Mouchiroud M, Efole B, Gélinas Y, Verreault M, Trottier J, Michaud A, Barbier O, Caron A.   +8 more
europepmc   +1 more source

Metabolism of bile acids

Metabolism of bile acids
Bile acids are biosynthesized from cholesterol in the liver. Cholic acid (CA), chenodeoxycholic acid (CDCA), and deoxycholic acid (DCA) are major bile acids in humans. Neutral (classical) pathway is the major pathway of the bile acid biosynthesis in adult humans, which starts from 7α-hydroxylation of cholesterol, catalyzed by cholesterol 7α-hydroxylase
openaire   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

<i>Allium mongolicum</i> Regel flavonoids promote intestinal health in goats by regulating bile acid metabolism and gut microbiota. [PDF]

mSystems
Yang R, Yu A, Xie Y, Zhang X, Guo B, Xu L, Tao W, Ma Y, Huang Y, Cao Y, Liu W, Lei Z.   +11 more
europepmc   +1 more source

Micro‐ and nanoplastics in gastrointestinal disorders: Mapping the translational gap between exposure, biomonitoring, and pathogenic mechanisms

BMEMat, EarlyView.
This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao, Yujie Luo, Chuanda Zhu, Yanwei Hu   +3 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Crosstalk between CD8+ T cells and systemic bile acid metabolism shapes antiviral immunity and immunopathology. [PDF]

JCI Insight
Richter FC, Keszei Z, Viczenczova C, Baumgartner M, Colaço HG, Siller M, Holnsteiner L, Baazim H, Hofmann A, Burrett A, Schönbichler A, Endler L, Wong JXE, Antonio-Herrera L, Petrenko O, Amman F, Genger JW, Fuchs CD, Scharnagl H, Marschall HU, Reiberger T, Lang KS, Campbell C, Trauner M, Bergthaler A.   +24 more
europepmc   +1 more source

Probiotic spore‐based bioresponsive drug delivery for reversing inflammatory bowel disease and its associated anxiety and depression

BMEMat, EarlyView.
A probiotic spore‐based drug delivery system (BCS‐Que@ApNPs) provides excellent targeted delivery, bioresponsive drug release, and long‐term retention (over 48 h), making it suitable for oral treatment of inflammatory bowel disease and its associated anxiety and depression.
Qingling Song, Beiyang Xue, Yao Li, Chuangxi Zhou, Junfei Yang, Yunfei Li, Lingwen Ding, Yun Zhang, Hongjuan Zhao, Lei Wang   +9 more
wiley   +1 more source