Results 41 to 50 of about 26,722 (309)

Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)[S]

Journal of Lipid Research, 2012
The apical Na+-dependent bile salt transporter (ASBT/SLC10A2) is essential for maintaining the enterohepatic circulation of bile salts. It is not known when Slc10a2 evolved as a bile salt transporter or how it adapted to substantial changes in bile salt ...
Daniël A. Lionarons, James L. Boyer, Shi-Ying Cai   +2 more
doaj   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Subcellular organization of bile acid amidation in human liver: a key issue in regulating the biosynthesis of bile salts

Journal of Lipid Research, 2000
To extend our knowledge of how the synthesis of free bile acids and bile salts is regulated within the hepatocyte, bile acid-CoA:amino acid N-acyltransferase and bile acid-CoA thioesterase activities were measured in subcellular fractions of human liver ...
Karianne Solaas, Anne Ulvestad, Odd Söreide, Bengt Frode Kase   +3 more
doaj   +1 more source

Bile Acids and Bile Salts of the Arabian Gulf Catfish Arius Bilineatus, Val

The FASEB Journal, 2015
Catfish gall bladders were collected from freshly caught catfish. Bile solution was collected by rupturing the gall bladder. The bile solution was freeze dried and extracted with chloroform:methanol (1:2). The solvent mixture was evaporated and the residue was extracted with methanol.
Jassim Al‐Hassan, Sosamma Oommen, Bincy Paul, Mohammad Afzal   +3 more
openaire   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

16S ribosomal ribonucleic acid sequencing reveals bile microbiome features in gallstone disease and their links to blood lipid subtypes

Frontiers in Microbiology
BackgroundGallstone disease (GSD) represents a major global health burden with complex pathophysiology involving bile microbiome dysbiosis and metabolic dysfunction.
Shijie Wang, Yongxing Ding, Cheng Cai, Mingrui Ou, Chunshen Niu   +4 more
doaj   +1 more source

Bile salts of the coelacanth, Latimeria chalumnae.

Journal of Lipid Research, 1984
Bile salts of the coelacanth, Latimeria chalumnae, Smith, have been analyzed and shown to have three bile alcohols, latimerol, 5 alpha-cyprinol, and 5 alpha-cholestane-3 beta, 7 alpha,-12 alpha,25,26-pentol, two C24 bile acids, chenodeoxycholic acid and ...
K Kihira, Y Akashi, S Kuroki, J Yanagisawa, F Nakayama, T Hoshita   +5 more
doaj   +1 more source

Hydrogel‐Based Functional Materials: Classifications, Properties, and Applications

Advanced Materials Technologies, EarlyView.
Conductive hydrogels have emerged as promising materials for smart wearable devices due to their outstanding flexibility, multifunctionality, and biocompatibility. This review systematically summarizes recent progress in their design strategies, focusing on monomer systems and conductive components, and highlights key multifunctional properties such as
Zeyu Zhang, Zao Cheng, Patrizio Raffa
wiley   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

BILE SALT METABOLISM AS INFLUENCED BY PURE AMINO ACIDS AND CASEIN DIGESTS [PDF]

Journal of Experimental Medicine, 1949
A non-protein diet supplemented with vitamins fed to a bile fistula dog caused marked reduction in cholic acid and taurocholic acid formation. A mixture of pure amino acids, essential for growth, promoted taurocholic acid production for a limited period.
W. B. Hawkins, P. C. Hanson, R. W. Coon, R. Terry   +3 more
openaire   +2 more sources