Results 111 to 120 of about 59,630 (258)

General Movement Assessment in infancy and later cognitive outcomes: A systematic review and meta‐analysis

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Aim To evaluate whether the General Movement Assessment (GMA) in infancy is associated with later cognitive outcomes from early childhood through adulthood. Method Cohort and case–control studies examining associations between Prechtl's GMA and cognitive outcomes from 6 months of age were eligible.
Sarah E. Hall   +11 more
wiley   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

open access: yesThe FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song   +2 more
wiley   +1 more source

Molecular dynamics simulations elucidate the misfolding mechanisms of secretion‐defective pancreatic lipase variants

open access: yesThe FEBS Journal, EarlyView.
Misfolding mutations in pancreatic lipase have been identified as potential contributors of chronic pancreatitis, an inflammatory disease of the human pancreas. Here, we describe the effect of these misfolding mutations on pancreatic lipase structure using molecular dynamics simulations and structural modeling.
Gyula Hoffka, András Szabó
wiley   +1 more source

Incidence of P200 pemphigoid: A nationwide study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen   +7 more
wiley   +1 more source

Enrichment‐Based Duplex PCR for Early Detection of Potentially Virulent Vibrio harveyi in Aquaculture

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Vibrio harveyi is an important bacterial pathogen in marine aquaculture, responsible for outbreaks affecting a wide range of fish species. Early detection of potentially virulent isolates in fish and environmental samples is essential for effective disease prevention and management, particularly under field conditions where the pathogen may be
Javier Barriga‐Cuartero   +4 more
wiley   +1 more source

GLP‐1 RA Plus SGLT2i Versus Monotherapy in MASLD and Type 2 Diabetes: Three Pairwise Target Trial Emulations

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated cardiovascular and metabolic benefits individually; however, the comparative effectiveness of combination therapy versus monotherapy in patients with metabolic dysfunction‐associated steatotic liver ...
Mohanad A. Alkuwaiti   +11 more
wiley   +1 more source

Alteration of Acid‐Binding Capacity of Various Nursery Pig Diets and Its Influence on Properties of Digesta Along the Gastrointestinal Tract

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT The objective of this study was to investigate the effects of reduced dietary acid‐binding capacity (ABC) by acidifiers on the properties of digesta along the gastrointestinal tract of pigs. In Exp. 1, 144 pigs at 21 d of age [6.5 ± 0.9 kg body weight (BW)] were housed in pens (3 pigs/pen). In Exp.
Hyunjun Choi, Sung Woo Kim
wiley   +1 more source

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