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Digestive and Liver Disease, 2010
Bile salts have a crucial role in hepatobiliary and intestinal homeostasis and digestion. Primary bile salts are synthesized by the liver from cholesterol, and may be modified by the intestinal flora to form secondary and tertiary bile salts. Bile salts are efficiently reabsorbed from the intestinal lumen to undergo enterohepatic circulation.
Maillette de Buy Wenniger, Lucas +1 more
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Bile salts have a crucial role in hepatobiliary and intestinal homeostasis and digestion. Primary bile salts are synthesized by the liver from cholesterol, and may be modified by the intestinal flora to form secondary and tertiary bile salts. Bile salts are efficiently reabsorbed from the intestinal lumen to undergo enterohepatic circulation.
Maillette de Buy Wenniger, Lucas +1 more
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Bile salts and hydrodynamics of bile formation
Journal of Hepatology, 1989We report a novel method to assess bile secretory pressure using a Statham pressure transducer. The studies were performed in vivo in male Sprague-Dawley rats under pentobarbital anesthesia. Maximal secretory pressure averaged 21.8 +/- 1.1 (S.D.) cmH2O.
Cotting J, Reichen J
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Bile Salt Structure and Phase Equilibria in Aqueous Bile Salt and Bile Salt-Lecithin Systems
Hepatology, 1984The hydrophilic-hydrophobic balance of bile salt monomers can be readily quantified by their elution sequence during reverse-phase high-performance liquid chromatography. Such studies have demonstrated that subtle variations in bile salt structure have profound effects on the hydrophilic-hydrophobic balance of this important ...
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Effects of bile salts on bile formation in rabbits
Life Sciences, 1986The effects of different species of bile salts: deoxycholate, taurochenodeoxycholate, ursodeoxycholate, glycodeoxycholate, tauroursodeoxycholate, chenodeoxycholate and cholate (DCA, TCDC, UDCA, GDCA, TUDC, CDCA, CA) on bile secretion were examined in anesthetized rabbits using two different infusion routes.
K, Miyasaka, K, Kitani
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The role of bile salts in digestion
Advances in Colloid and Interface Science, 2011Bile salts (BS) are bio-surfactants present in the gastrointestinal tract (GIT) that play a crucial role in the digestion and absorption of nutrients. The importance of BS for controlled release and transport of lipid soluble nutrients and drugs has recently stimulated scientific interest in these physiological compounds.
Julia Maldonado-Valderrama +3 more
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Chemistry and Physics of Lipids, 1991
Calcium binding to bile salt monomers and micelles is an important issue with respect to the possible (but rare) precipitation of calcium bile salts in the gallbladder. In the present work the binding of Ca2+ to six bile salts was measured in solutions containing 2 to 100 mM bile salts by means of a calcium-sensitive dye, murexide, which determines the
E, Baruch +3 more
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Calcium binding to bile salt monomers and micelles is an important issue with respect to the possible (but rare) precipitation of calcium bile salts in the gallbladder. In the present work the binding of Ca2+ to six bile salts was measured in solutions containing 2 to 100 mM bile salts by means of a calcium-sensitive dye, murexide, which determines the
E, Baruch +3 more
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The solubilization of quinine by bile salts
Journal of the American Pharmaceutical Association (Scientific ed.), 1947Abstract From turbidimetric titrations of bile salts with quinine and turbidity‐concentration curves of colloidal solutions of quinine‐dehydrocholic acid and tauroglycocholic acid complexes, it has been concluded that solubilization takes place through the formation of micelles composed of quinine and bile salts.
S, MUKHERJEE, R P, BANERJEE
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Control of Bile Salt Synthesis
Nature New Biology, 1972THE regulation of bile salt synthesis in man is still poorly understood. The human liver synthesizes a trihydroxy and a dihydroxy bile acid, cholic and chenodeoxycholic acid, each conjugated with glycine or taurine. These, together with deoxycholic acid, a dihydroxy bile acid which results from the 7-α dehydroxylation of cholic acid by intestinal ...
T S, Low-Beer, E W, Pomare, J S, Morris
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