Results 121 to 130 of about 7,014 (156)
A continuous fluorescence assay for simple quantification of bile salt hydrolase activity in the gut microbiome. [PDF]
Sci Rep, 2019 Brandvold KR +3 more
europepmc +1 more source
The complex structure of bile salt hydrolase from Lactobacillus salivarius reveals the structural basis of substrate specificity. [PDF]
Sci Rep, 2019 Xu F +5 more
europepmc +1 more source
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Probiotic Bile Salt Hydrolase: Current Developments and Perspectives
Applied Biochemistry and Biotechnology, 2009Probiotic has modernized the current dietetic sense with novel therapeutic and nutritional benefits to the consumers. The presence of bile salt hydrolase (BSH) in probiotics renders them more tolerant to bile salts, which also helps to reduce the blood cholesterol level of the host.
Ashok Pandey +2 more
exaly +3 more sources
Determination of Bile Salt Hydrolase Activity in Bifidobacteria
2021Bile salt hydrolase (BSH) activity is a desirable trait in putative probiotic bacteria, such as those belonging to the Bifidobacterium genus. On the one hand, bile salt hydrolysis is considered to represent a bile detoxification mechanism for gut commensal bacteria and thus the presence of this activity was believed to be a predictor of bile tolerance ...
Lorena, Ruiz +2 more
openaire +2 more sources
Applied Microbiology and Biotechnology, 2000
Bacterial bile salt hydrolysis is considered a risk factor for the development of colon cancer because of the risk of forming harmful secondary bile salts after an initial deconjugation step. In this study, the influence of enhanced bacterial bile salt transformation by the bile salt hydrolase-active Lactobacillus reuteri was studied in batch culture ...
P, De Boever +5 more
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Bacterial bile salt hydrolysis is considered a risk factor for the development of colon cancer because of the risk of forming harmful secondary bile salts after an initial deconjugation step. In this study, the influence of enhanced bacterial bile salt transformation by the bile salt hydrolase-active Lactobacillus reuteri was studied in batch culture ...
P, De Boever +5 more
openaire +2 more sources
Bile salt toxicity to some bifidobacteria strains: Role of conjugated bile salt hydrolase and pH
Canadian Journal of Microbiology, 2000The purpose of this work was to study some aspects of bile salt toxicity towards bifidobacteria. A strain (Bifidobacterium coryneforme ATCC 25911) was selected for its lack of conjugated bile salt hydrolase activity (CBSH-), and was used with three deconjugating strains (CBSH+), for study of their growth and viability in the presence of two ...
J P, Grill, S, Perrin, F, Schneider
openaire +2 more sources
Biotechnology Letters, 2015
Changes of bile salt tolerance, morphology and amount of bile acid within cells were studied to evaluate the exact effects of bile salt hydrolase (BSH) on bile salt tolerance of microorganism.The effect of BSHs on the bile salt tolerance of Lactococcus lactis was examined by expressing two BSHs (BSH1 and BSH2). Growth of L.
Jie, Bi +3 more
openaire +3 more sources
Changes of bile salt tolerance, morphology and amount of bile acid within cells were studied to evaluate the exact effects of bile salt hydrolase (BSH) on bile salt tolerance of microorganism.The effect of BSHs on the bile salt tolerance of Lactococcus lactis was examined by expressing two BSHs (BSH1 and BSH2). Growth of L.
Jie, Bi +3 more
openaire +3 more sources
Bile salt hydrolase acyltransferase activity expands bile acid diversity
NatureBile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-soluble vitamins while shaping the gut microbiome because of their antimicrobial properties1-4. Here we identify the enzyme responsible for a mechanism of BA metabolism by the gut microbiota involving amino acid conjugation to the acyl-site of BAs, thus ...
Douglas V. Guzior +14 more
openaire +2 more sources